We have 53 Medicine PhD Projects, Programmes & Scholarships in Jordanstown

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Medicine

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Jordanstown  United Kingdom

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Medicine PhD Projects, Programmes & Scholarships in Jordanstown

We have 53 Medicine PhD Projects, Programmes & Scholarships in Jordanstown

How does Case-Based-Learning Impact Medical Student Experience during Longitudinal Integrated Clerkships?

  Research Group: Centre for Medical Education
The application of knowledge to the clinical setting in undergraduate medicine can be challenging, particularly where students feel the ‘jump’ from the more theoretically focussed years 1 and 2 to the clinically orientated year 3. Read more

Understanding individual radiation risks

  Research Group: The Patrick G Johnston Centre for Cancer Research
Radiation represents both a key tool in the treatment of cancer, where it is used to kill tumours, and an environmental hazard where exposure can lead to a number of negative health consequences. . Read more
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Novel regulation pathways of Neutrophil Serine Protease (NSP) activation

In chronic lung diseases such as Cystic Fibrosis lung disease or Chronic Obstructive Pulmonary Disease, the lung is susceptible to destruction of lung tissue by human cells that normally participate in removing bacteria from the lung. Read more

Tractable human distal lung organoid model as a new efficient tool to study mesenchymal-epithelial interactions in COPD

In this NC3Rs funded project we will use novel lung organoid model to study how  epigenetic modifications in lung-resident mesenchymal stromal cells regulate epithelial lung regeneration in the context of Chronic Obstructive Pulmonary Disease (COPD). Read more

Structure-based design of allosteric modulators for G protein-coupled receptors using molecular modelling and pharmacology experiments

Almost all physiological processes are regulated through the activation of G protein-coupled receptors (GPCRs). It has become widely accepted that most GPCRs possess binding sites spatially distinct from their natural ligand binding site (orthosteric site), termed as allosteric sites. Read more

Development of Nanomaterials for Targeting the Bacteria–Host Interface in Cystic Fibrosis Airways

The attachment of Pseudomonas aeruginosa (PA) to the airway mucus in the lungs of people with cystic fibrosis (CF) represents an important step in airway colonization and the subsequent development of lung infection. Read more

Probing the Dark Transcriptome: Leveraging Third-Generation RNA-Sequencing, Proteomics, and Deep Learning for the Discovery of Expressed Transcripts

This collaborative project with QUB cancer vaccine Spin-Out AilseVax, is focussed on developing computational methodologies for identifying and validating novel tumour-specific antigens (TSAs) in the “dark transcriptome/translatome from multi-omic and mass spectrometry (MS) data. Read more

Ultrahigh dose rate radiotherapy - Beamline validation and biological characterisation of the FLASH-SARRP.

This project will support research applying a new ultra-high dose-rate (“FLASH”) radiotherapy system. The FLASH-SARRP is a first of its kind platform enabling the delivery of photon-FLASH radiotherapy in preclinical models. Read more

Core Outcome Set Taskforce for Cystic Fibrosis (COST-CF): a patient-initiated core outcome set for CF

  Research Group: Wellcome-Wolfson Institute for Experimental Medicine
People living with cystic fibrosis (CF) want meaningful and consistent outcomes in clinical trials. Clinical trials compare a drug with a dummy treatment, or one treatment with another. Read more

Nanocrystals-in-nanofibres as a promising strategy for the delivery of poorly soluble actives

One of the most challenging issues that the pharmaceutical industry face is poor aqueous solubility of drugs. 90% of candidate molecules within the discovery pipelines face solubility issues, posing significant hurdles to their clinical translation. Read more

Functionalised silicone elastomers for controlled release drug delivery

It is increasingly acknowledged that drug delivery is a key factor in developing new medicines, and that new polymeric biomaterials will play a critical role in driving innovation. Read more

Development of clinically relevant test methods to analyse current commercialised products and support the development of next-generation intermittent catheter products

Intermittent catheterisation (IC) is a procedure in which patients with bladder management problems void urine by inserting a catheter, possessing a drainage eyelet at the distal end, into the urethral opening which facilitates urine drainage from the bladder into an appropriate receptacle. Read more

Novel, biobased, recyclable polymer for high-barrier blister packaging for pharmaceuticals

Project Introduction. Blister packaging is one of the main packaging formats for pharmaceuticals. It provides convenience for patients to extract tablets by a push-through action, and the materials used provide barrier to moisture or oxygen in order to guarantee the shelf life of the tablets. Read more

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