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We have 26 Pharmacology PhD Projects, Programmes & Scholarships in Jordanstown

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Medicine

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Jordanstown  United Kingdom

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Pharmacology PhD Projects, Programmes & Scholarships in Jordanstown

We have 26 Pharmacology PhD Projects, Programmes & Scholarships in Jordanstown

Structure-based design of allosteric modulators for G protein-coupled receptors using molecular modelling and pharmacology experiments

Almost all physiological processes are regulated through the activation of G protein-coupled receptors (GPCRs). It has become widely accepted that most GPCRs possess binding sites spatially distinct from their natural ligand binding site (orthosteric site), termed as allosteric sites. Read more

Novel strategies and innovative technologies to produce amorphous solid dispersion

Poor drug solubility presents a major challenge in drug product development of oral solid dosage (OSD) forms. However, many new development compounds exhibit poor solubility and only a few of them reach market approval. Read more

Microneedle delivery systems for minimally-invasive patient diagnosis/monitoring

In this project, a novel type of integrated system will be investigated that will by-pass the skin barrier. On its surface will be multiple microscopic needles that pierce the skin without causing any pain – the sensation is said to feel like a cat’s tongue or sharkskin. Read more

Does one size fit all for antimicrobial delivery via nanoparticles

Antimicrobial resistant bacteria are a growing problem and new ways are needed to target bacterial infections more efficiently. One way in which bacteria can avoid therapeutics is via intracellular infection, where they hide within our own cells. Read more

Regulation of CaaX protein processing

USP17 is over-expressed in a range of primary tumours including NSCLC, breast, colorectal, cervical, ovarian and osteosarcoma and its depletion has been shown to block the growth of cells from all these cancer types, as well as the migration of a range of cancer cells (NSCLC, breast, ovarian, osteosarcoma).    . Read more

Designing and evaluating novel nanotherapeutics to enhance the effectiveness of radiotherapy in the treatment of solid cancers.

One in two cancer patients will receive radiotherapy as part of their treatment. For patients with a localised cancer diagnosis effective radiotherapy represents the best chance of a curative outcome, however, is not without risk. Read more

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