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Latest University of York, Department of Chemistry PhD Projects, Programmes & Scholarships
We have 17 Latest University of York, Department of Chemistry PhD Projects, Programmes & Scholarships
We have 17 Latest University of York, Department of Chemistry PhD Projects, Programmes & Scholarships
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Synthesis of macrocycles and medium-sized rings via new ring expansion approaches
Summary. Macrocycles (12+ membered rings) and medium-sized rings (8–11-membered) are cyclic molecules with great potential in many scientific fields and technologies – especially in medicinal chemistry. Read more
Development of chemical probes to monitor enzyme activity involved in muscular dystrophy
Background. Cell surface proteins are modified with diverse carbohydrate structures, or glycans, that play important roles in signalling, cell-pathogen interactions, and communication between cells and their environment. Read more
Catch a radical in flight: understanding photoredox catalysis with electron donor-acceptor complexes
Background. Generation of free radical intermediates by visible light irradiation of Ir or Ru complexes has revolutionised synthetic radical chemistry in the last decade. Read more
Photocatalytic and catalytic conversion of carbon dioxide to C-C coupled liquid products
Background. There is an urgent need to develop technologies that reduce the detrimental effects of climate change. Chemistry can contribute significantly by using renewable energy to transform waste CO2 to a useful product or storable liquid. Read more
Redox-active salts for sustainable energy storage technologies
Background. The climate crisis requires us to transform the way that we generate, store and use energy. Two aspects of energy storage are of interest to this project. Read more
Understanding Solvation in Hydrogen-Transfer Reactions in Deep Eutectic Solvents
Background. Solvents play a fundamental role in synthesis. Unfortunately, many commonly used volatile organic solvents (VOS) are harmful to humans and/or the environment. Read more
Using cryogenic electron microscopy (cryoEM) to explore bacterial spore germination
Background. Many bacterial species form spores. Not only are spores the most robust biological structures known, they also have important roles in disease, food spoilage, and biotechnology. Read more
Catalytic Antibiotic Activation: Tackling Resistance with Artificial Metalloenzymes
Background. Antimicrobial resistance is a global health crisis and new antibacterial strategies are urgently needed, including methods for the targeted activation of antibiotics in pathogenic bacteria. Read more
A Modular Approach to Sustainable Photocatalysts
Background. The use of light to promote chemical reactions underpins a significant number of recent developments in hydrogen generation, CO2 conversion and remarkable new transformations for synthetic chemistry. Read more
Unlocking challenges in complex molecular synthesis (e.g. natural products) using high throughput experimentation and digital chemistry
Background. For well over 100 years there has been a rich tradition of applying new reaction chemistries in the pursuit of synthesising complex molecular structures. Read more
Getting the Gold In – Efficient Auration Reactions
Background. Organogold(III) chemistry is much less explored that that of gold(I), as it is difficult to form the complex from the ligand. Read more
Beyond Transaminases: Evolution of native Amine Dehydrogenases for Chiral Primary Amine Synthesis.
Background. Chiral amines are important functional groups that feature in up to 50% of small molecule drugs. The chemistry use to make them is often non-selective, hazardous or toxic and so there is significant pressure to develop green and sustainable methods of chiral amine synthesis. Read more
Sensitivity Enhancement in Nuclear Magnetic Resonance (NMR) by Para-hydrogen Induced Hyperpolarisation
Summary. This project will use hyperpolarisation to improve the ability of NMR to detect an array of important target molecules – such as chemical agents, metabolites and drugs. Read more
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