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Biomedical Engineering PhD Projects, Programs & Scholarships in Leeds

We have 18 Biomedical Engineering PhD Projects, Programs & Scholarships in Leeds

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Showing 1 to 15 of 18
  A ‘Metastasis-On-A-Chip’ Microphysiological Model of Cancer Metastasis to Bone
  Dr M Amer, Dr V Pensabene, Prof F Meldrum
Application Deadline: 1 July 2020

Funding Type

PhD Type

Bone is a frequent site of cancer metastases and usually indicates poor clinical prognosis. Metastasis of tumour cells in the bone marrow is a dynamic process, and cell behaviour is regulated by three-dimensional (3D) cell-cell and cell-matrix interactions with its microenvironment.
  Developing a tissue engineered/polyurethane blood vessel using bioengineering techniques
  Research Group: Chemistry and Biosciences
  Prof S Rimmer, Prof A M Graham, Dr K Riches-Suman
Applications accepted all year round

Funding Type

PhD Type

Vein graft failure is a significant issue in cardiovascular disease patients, with restenosis caused by alterations in flow patterns leading to remodelling and disease progression.
  Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents
  Research Group: Institute of Cancer Therapeutics
  Dr R Falconer, Dr S Shnyder
Applications accepted all year round

Funding Type

PhD Type

Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs).
  Ankle moment contribution in everyday tasks: effects of ageing
  Research Group: Medical Engineering
  Dr J Buckley
Applications accepted all year round

Funding Type

PhD Type

There is a fall on stairs every 90 seconds in the UK, and an estimated 250,000 non-fatal accidents which are serious enough to merit a trip to A&E.
  Glioblastoma: A Nanotechnology Approach for Glioblastoma Targeted Therapy
  Research Group: Medical Engineering
  Dr F Sefat, Dr M Najafzadeh
Applications accepted all year round

Funding Type

PhD Type

Glioblastoma is a type of brain cancer. It’s the most common type of malignant brain tumor among adults and it is usually very aggressive, which means it can grow fast and spread quickly.
  Core and core-shell nanomaterials synthesis for Optoelectronics
  Research Group: Chemistry and Biosciences
  Dr S Hickey, Dr W Martin
Applications accepted all year round

Funding Type

PhD Type

Nanoscience and technology, which involves the manipulation of materials using the property of size to bring about specific desired changes in the electronic structure of materials, has proven to be a powerful additional tool permitting the materials scientist to effect greater control over the charge transport properties in materials.
  3D Electrospinning - shaping the structure of tissue engineering scaffolds
  Research Group: Advanced Materials Engineering
  Dr P Twigg
Applications accepted all year round

Funding Type

PhD Type

Electrospinning applies a high voltage to a polymer solution to create fine fibres that form non-woven mats. These can be used as scaffolds for tissue engineering, acting as the extracellular matrix and supporting the cells.
  Functional Evaluation of the Meniscus and Meniscus Replacement using MRI
  Dr R K Wilcox
Applications accepted all year round

Funding Type

PhD Type

The aim of this PhD study is to develop new methods for examining the human knee joint under load using magnetic resonance imaging (MRI).
  Nanoparticle-based Therapeutics to Combat Multidrug Resistance and Biofilms in Chronic Wound Infections
  Research Group: Molecular and Nanoscale Phsyics
  Dr Z Ong, Dr J R McLaughlan
Applications accepted all year round

Funding Type

PhD Type

Chronic wound infections are a significant and fast-growing global healthcare problem compounded by the widespread occurrence of antibiotic-resistant bacteria.
  How protective signals from the gut modify neuronal activity and behaviour, using C. elegans as a model system.
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr P van Oosten-Hawle, Prof N Cohen
Applications accepted all year round

Funding Type

PhD Type

Amyloid protein misfolding leading to loss of neuronal function are fundamental pathogenic mechanisms of numerous age-associated neurodegenerative diseases, including Alzheimer’s (AD).
  Learning from plant cell walls as a path for innovations in food and material sciences
  Dr Y Benitez-Alfonso, Dr C Bosch
Applications accepted all year round

Funding Type

PhD Type

The research will dissect the structural factors controlling cell walls and cell communication for two main purposes. to improve the health value of food crops and to design strategies for the valorisation of wasted plant materials.
  Structural insights into ligand binding and channel gating in ATP-gated P2X7 receptor
  Research Group: School of Biomedical Sciences
  Dr L H Jiang, Dr S Muench
Applications accepted all year round

Funding Type

PhD Type

P2X7 receptor, belonging to the ATP-gated ion channel P2X receptor family, exhibits distinct functional and pharmacological properties that are crucial for its role in innate immunity and inflammatory diseases and cancers (Jiang et al., 2013; Caseley et al., 2014; Roger et al., 2014; Wei et al., 2018).
  Neurocomputational mechanisms of modularity in human motor control
  Research Group: School of Biomedical Sciences
  Dr I Delis
Applications accepted all year round

Funding Type

PhD Type

Human motor behaviour is the outcome of the combined action of an extensive neural circuit that generates and controls movement and the mechanical properties of the human body.
  Epigenetic therapy using ultrasound-mediated microbubble drug delivery for cancer treatment
  Dr E Valleley, Dr L Coletta
Applications accepted all year round

Funding Type

PhD Type

The project is an interdisciplinary, pre-clinical study that aims to investigate the response of human tumour cells to treatment with epigenetic inhibitors (such as DNA methyltransferase inhibitors), as a potential combination therapy for colorectal cancer (CRC).
  Developing pluripotent stem cell models of inherited retinal diseases
  Prof C A Johnson
Applications accepted all year round

Funding Type

PhD Type

Background. Inherited retinal dystrophies are a leading cause of blindness and visual loss in the UK working age population. However, despite the widespread diagnostic use of next-generation sequencing, a molecular genetic diagnosis is unavailable for many patients world-wide.
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