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Biophysics PhD Projects, Programs & Scholarships in Leeds

We have 9 Biophysics PhD Projects, Programs & Scholarships in Leeds

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Showing 1 to 9 of 9
  Structural and Biophysical Characterisation of Novel Membrane Protein Ion Channels (Chinese candidates / China mainland only)
  Research Group: School of Biomedical Sciences
  Dr C Pliotas
Application Deadline: 8 January 2020

Funding Type

PhD Type

Research in the Pliotas group (https://www.pliotasgroup.org/) focuses on the investigation of molecular mechanisms which underlie the structure and function of integral membrane proteins, in particular ion channels.
  Epigenetic therapy using ultrasound-mediated microbubble drug delivery for cancer treatment
  Dr E Valleley, Dr L Coletta
Applications accepted all year round

Funding Type

PhD Type

The project is an interdisciplinary, pre-clinical study that aims to investigate the response of human tumour cells to treatment with epigenetic inhibitors (such as DNA methyltransferase inhibitors), as a potential combination therapy for colorectal cancer (CRC).
  Synthetic Virology: Development of gene delivery vectors/synthetic vaccines
  Research Group: Astbury Centre for Structural Molecular Biology
  Prof P G Stockley
Applications accepted all year round

Funding Type

PhD Type

There is worldwide interest in exploiting our modern understanding of genomics to target gene expression therapeutically via a variety of mechanisms, such as transgene insertion and CRISPR-Cas gene editing.
  Defining a novel assembly pathway in ssRNA viruses using X-ray footprinting.
  Prof P G Stockley
Applications accepted all year round

Funding Type

PhD Type

Project co-supervised by Prof. Peter Stockley at Leeds and Prof. Reidun Twarock at University of York, as part of the White Rose network "Structural and Mechanistic Biology at the RNA/Ligand Interface".
  Mathematical Virology: A New Mathematical Approach to Viral Evolution Grounded in Experiment
  Research Group: Astbury Centre for Structural Molecular Biology
  Prof P G Stockley
Applications accepted all year round

Funding Type

PhD Type

Mathematical modelling of natural phenomena has the potential to be predictive but requires direct verification by experiment. Such models can then be very powerful indicators of our understanding and they permit in silico simulations of situations that are difficult to test experimentally.
  EPSRC Centre for Doctoral Training in Soft Matter for Formulation and Industrial Innovation (SOFI2 CDT)

Funding Type

PhD Type

16 fully funded, four-year PhD studentships are available in the EPSRC Centre for Doctoral Training in Soft Matter for Formulation and Industrial Innovation (SOFI2 CDT) commencing in September 2019, for graduates in the physical and biological sciences, mathematics and engineering.
  Pattern Formation (Applied Nonlinear Dynamics): understanding the formation and stability of complex patterns such as quasipatterns, spatio-temporal chaos or turbulent spirals
  Prof A M Rucklidge
Applications accepted all year round

Funding Type

PhD Type

Regular patterns, such as stripes, squares and hexagons, are ubiquitous in nature, and their formation and stability are governed by the intricate and complex interactions of symmetry and nonlinearity.
  An integrated approach to the study of cellular interactions with amyloid
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr E W Hewitt, Prof S E Radford
Applications accepted all year round

Funding Type

PhD Type

The formation of insoluble amyloid fibrils is associated with a spectrum of human disorders, the amyloidoses, which include Alzheimer’s, Parkinson’s, type 2 diabetes and dialysis related amyloidosis (DRA).
  Development and characterisation of synthetic ion channel binding proteins.
  Research Group: School of Biomedical Sciences
  Dr J D Lippiat, Dr D Tomlinson
Applications accepted all year round

Funding Type

PhD Type

We are developing methods to identify novel proteins, Affimers, that recognise extracellular domains of ion channels. These have applications in various aspects of biology, from tools to visualise the location and distribution of ion channels in native tissue, to novel modulators of ion channel function.
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