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Biophysics PhD Projects, Programs & Scholarships in Leeds

We have 34 Biophysics PhD Projects, Programs & Scholarships in Leeds

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Physical Sciences

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Leeds  United Kingdom

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We have 34 Biophysics PhD Projects, Programs & Scholarships in Leeds

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Biological physics of cell trafficking: Immune cell homing at the blood vessel wall

  Research Group: School of Physics and Astronomy
Cell trafficking is vital to all multicellular life and key in diseases such as cancer. In this PhD project, you will devise new methods to study how immune cells that circulate in the blood stream find and bind to sites of inflammation and how cancer cells hijack the system to metastasize. Read more

Mapping the nanoscale organisation of cellular proteins across complex topographies

  Research Group: School of Physics and Astronomy
Super-resolution fluorescence microscopy techniques make it possible to visualise nanoscale structures in cells, by going beyond the capabilities of conventional microscopy. Read more

Developing a high-speed fluorescence imaging flow cytometer

  Research Group: School of Physics and Astronomy
Flow cytometry is routinely used as a high-throughput method for characterising and screening cells in biology and medicine. This ranges from identification of suitable drug treatments for patients diagnosed with cancer to biophysical studies of cells with rare (1 in a million) structures or protein expression profiles. Read more

Developing the next generation of biomaterial structural characterisation

  Research Group: School of Physics and Astronomy
Folded protein hydrogels are an exciting new class of biomaterial which possess specific biological functionality, enabling dynamic changes in mechanical and structural properties in response to biomolecular cues. Read more

Microfluidic Deformation for Intracellular Delivery

  Research Group: School of Physics and Astronomy
The aim of this PhD to study a high-throughput microfluidic platform to facilitate the controlled uptake of nanoparticles into live cells for intracellular probes (for reporting on cancer cells), respectively, using experimental methods. Read more

Cellular logistics: Biological physics of selective protein and gene transport across the nuclear envelope

  Research Group: School of Physics and Astronomy
The coordinated transport of proteins and nucleic acids between the nucleus and the cytosol is vital for proper gene expression and cell function, and hijacked by viruses to propagate. Read more

Understanding and controlling β-strand mediated PPIs using bespoke chemical modifications

  Research Group: School of Chemistry
Chemical probes are advantageous in studying the molecular mechanisms of health and disease; they uniquely allow temporary and titratable modulation of a target protein’s function, permitting evaluation of its functional role. Read more

Using Dynamic Combinatorial Selection Methods to Identify Chemical Modifications of Protein Function

  Research Group: School of Chemistry
This PhD studentship will exploit chemical biology approaches to understand and manipulate the aggregation behaviour of α-synuclein, an intrinsically disordered protein which plays a key role in the neurodegenerative condition. Read more

MRC DiMeN Doctoral Training Partnership: Elucidating a structural basis for pathogenic mutations in B cell lymphoma

Cancer is a major health problem worldwide and it is believed that 1 in 2 people will develop a form of cancer in their lifetime. Despite recent progress in our understanding of cancer cell biology, current treatments are only effective for some patients. Read more

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