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Cancer / Oncology PhD Projects, Programs & Scholarships in Leeds

We have 23 Cancer / Oncology PhD Projects, Programs & Scholarships in Leeds

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  New strategies in integrin antagonism
  Research Group: Institute of Cancer Therapeutics
  Dr H Sheldrake
Applications accepted all year round

Funding Type

PhD Type

The integrins are a family of transmembrane receptors which mediate cell-cell and cell-ECM adhesion, and signalling across the cell membrane involved in pathways controlling cell migration, proliferation, differentiation, cell survival and apoptosis.
  Gastroesophageal reflux in respiratory disease: pathogenic role and improved management
  Prof L Houghton
Applications accepted all year round

Funding Type

PhD Type

Gastroesophageal reflux (GER) is associated with many lung diseases, including but not limited to idiopathic pulmonary fibrosis (IPF), non-IPF interstitial lung disease (ILD), chronic obstructive pulmonary disease (COPD), cystic fibrosis (CF), non-CF bronchiectasis, asthma and idiopathic chronic cough.
  Enhancing Oncolytic Virus-induced Immunotherapy using Eicosapentaenoic Acid (EPA)
  Dr F Errington-Mais, Dr MA Volpato
Applications accepted all year round

Funding Type

PhD Type

Breast cancer is the most commonly diagnosed cancer in women with triple-negative breast cancer (TNBC) having the worst prognosis, highest death rate and lowest overall survival.
  Epigenetic therapy using ultrasound-mediated microbubble drug delivery for cancer treatment
  Dr E Valleley, Dr L Coletta
Applications accepted all year round

Funding Type

PhD Type

The project is an interdisciplinary, pre-clinical study that aims to investigate the response of human tumour cells to treatment with epigenetic inhibitors (such as DNA methyltransferase inhibitors), as a potential combination therapy for colorectal cancer (CRC).
  The functional characterization of the tumour suppressor gene CSMD1 in breast cancer
  Dr S Bell
Applications accepted all year round

Funding Type

PhD Type

CUB and Sushi multiple domains protein 1 (CSMD1) maps to 8p23, a region deleted in many cancers including breast cancer. Our previous work has established that CSMD1 is an independent prognostic marker in ductal breast cancer, with reduced expression associated with high tumour grade and poor survival1.
  Identification and functional characterisation of BRIT1/MCPH1 synthetic lethal genes to treat breast and ovarian cancer
  Dr S Bell, Prof C A Johnson
Applications accepted all year round

Funding Type

PhD Type

Women who have undergone surgery for breast and ovarian cancer often have additional chemotherapy to kill residual cancer cells and prevent recurrence.
  Design, synthesis and evaluation of protease-activated anti-cancer prodrugs
  Research Group: Institute of Cancer Therapeutics
  Dr R Falconer, Prof P Loadman
Applications accepted all year round

Funding Type

PhD Type

Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis.
  Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents
  Research Group: Institute of Cancer Therapeutics
  Dr R Falconer, Dr S Shnyder
Applications accepted all year round

Funding Type

PhD Type

Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs).
  Polysialyltransferases as a target in metastatic cancer
  Research Group: Institute of Cancer Therapeutics
  Dr R Falconer, Dr S Shnyder
Applications accepted all year round

Funding Type

PhD Type

Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases.
  International PhD Academy: Medical Research

Funding Type

PhD Type

Our vision is to impact locally, nationally and globally on biomedical and clinical research with a primary emphasis on health outcomes.
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