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We have 33 Cell Biology PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Leeds

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Cell Biology PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Leeds

We have 33 Cell Biology PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Leeds

A Cell Biology PhD would give you the opportunity to take on a three to four-year research project into the inner workings of cells. Your research may involve investigating cell-to-cell communication, the potential use of stem cells, or researching the difference between cells from a healthy individual compared to those with a certain disease. Regardless, you’ll be contributing to your field.

What’s it like to do a PhD in Cell Biology?

A PhD in Cell Biology would allow you to gain an array of laboratory skills, most notably in cell culture, which is essential to any Cell Biology project. You’ll also use classic laboratory methods such as immunoassays, chromatography, and fluorescence assays.

Some typical research topics in Cell Biology include:

  • Understanding cell trafficking
  • Stem cell biology
  • Investigating the plasma membrane of a certain cell type
  • Comparing cells from a diseased and non-diseased state
  • Investigating the cell cycle
  • Understanding cell communication
  • Investigating the regulation and consequences of programmed cell death

Day-to-day you’ll be performing experiments in the laboratory, creating graphs, analysing previously collected data, and discussing your work with your supervisor and colleagues. At the end of the final year of your project, you’ll submit a thesis of approximately 60,000 words and defend this during your viva exam.

Cell Biology programmes are most commonly advertised positions with full funding attached, meaning the general scope and goals of the work have been determined by the supervisor in advance and you apply to the project.

Writing a research proposal and suggesting your own research topic is uncommon in Cell Biology. As with most subjects within Biology, additional bench fees are required, which makes finding independent funding difficult.

Entry requirements

The entry requirements for most Cell Biology PhD programmes involve a Masters in a subject directly related to Biology, with at least a Merit or Distinction. If English isn’t your first language, you’ll also need to show that you have the right level of language proficiency.

PhD in Cell Biology funding options

The research council responsible for funding Cell Biology PhDs in the UK is the Biotechnology and Biological Sciences Research Council (BBSRC). They provide fully-funded studentships including a stipend for living costs, a consumables budget for bench fees and a tuition fee waiver. Students don’t apply directly to the BBSRC, you apply for advertised projects with this funding attached.

It’s difficult for Cell Biology PhD students to be ‘self-funded’ due to the additional bench fees. However, if you were planning to fund yourself it might be achievable (depending on your project) through the UK government’s PhD loan and part-time work.

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Investigation of antagonism of multiple RGD-binding integrins as a therapeutic strategy in advanced head and neck cancer

  Research Group: Institute of Cancer Therapeutics
Background. The integrins are a family of transmembrane receptors which mediate cell-cell and cell-ECM adhesion, and signalling across the cell membrane involved in pathways controlling cell migration, proliferation, differentiation, cell survival and apoptosis. Read more

Cancer: Inhibiting cell metabolism to enhance tumour cell death

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more

Metabolic reprogramming in cancer: starving tumors of essential nutrients to promote cell death

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more

Cancer: Repurposing drugs as new treatments for breast cancer

Breast cancer (BC) is the most common cancer, with over 1 million new cases diagnosed worldwide each year. For some types of BC, hormonal treatments have been very effective but one particular BC subtype, triple negative breast cancer (TNBC), is highly aggressive and lacks a targeted therapy. Read more

Cancer: Understanding the immunosuppressive role of fibroblast and macrophages in Breast cancer

Oncolytic viruses (OVs) preferentially infect and kill cancer cells, and their clinical efficacy has been demonstrated against a number of different cancers. The most clinically advanced OV is a genetically engineered herpes simplex virus (T-VEC) which expresses GMCSF to aid the development of anti-tumour immune responses; T-VEC is approved for the treatment of metastatic melanoma. Read more

Control and inhibition of virus replication

The Tuplin laboratory utilises a range of cutting-edge approaches to investigate how arboviruses - specifically Chikungunya, Dengue and Zika viruses - control replication and translation of their genomes through interactions between RNA structures, host cell proteins and non-coding RNA, and the potential of such RNA elements/interactions as novel therapeutic targets. Read more

Cancer: Epigenetic therapy using microbubble-mediated drug delivery for colorectal cancer

The project is an interdisciplinary, pre-clinical study that aims to investigate the response of human tumour cells to treatment with epigenetic inhibitors (including DNA methyltransferase inhibitors, HDAC inhibitors and/or vitamin C), as a potential combination therapy for colorectal cancer (CRC). Read more

Epigenetic regulation of skin wound healing

  Research Group: Chemistry and Biosciences
Skin in the largest organ in the human body consisting of epidermis, dermis and subcutis. It also contains epithelial appendages, including hair follicles and sweat glands. Read more

Immunotherapy: Killing Cancer using Dead Virus

It is now accepted that our immune systems can hold the key to treating otherwise incurable cancers. So-called “immunotherapy” is an increasingly common method of treating tumours, leading to impressive increases in patient responses. . Read more

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