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Molecular Biology PhD Projects, Programs & Scholarships in Leeds

We have 31 Molecular Biology PhD Projects, Programs & Scholarships in Leeds

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Showing 1 to 10 of 31
  Using massively-paralleled sequencing to find the cause of inherited conditions that affect the front of the eye
  Dr M Ali, Prof C Inglehearn
Applications accepted all year round
Eye diseases are a common cause of human disability and many of them are inherited. These include congenital as well as adult-onset conditions and diseases of ageing, and may involve abnormalities at the back of the eye or the anterior eye structures.
  Why do proteins aggregate under flow?
  Dr D Brockwell, Prof S E Radford
Application Deadline: 15 March 2019
The function and stability of proteins are intimately linked to their environment and consequently, changes in environmental factors such as pH can trigger conformational changes that in turn modulate protein function.
  Posttranslational modifications of the tumor suppressor PTCH1: characterisation and functional significance
  Dr N.A. Riobo-Del Galdo, Prof R.W. Bayliss
Application Deadline: 10 March 2019
PTCH1, the receptor of the Hedgehog family of proteins and a well-characterised tumor suppressor, is a 12-transmembrane protein with long intracellular N- and C-termini (1).
  Epigenetics and Cancer: Determining how Mistakes in V(D)J Recombination Trigger Leukaemias and Lymphomas
  Research Group: School of Molecular and Cellular Biology
  Dr J Boyes
Applications accepted all year round
V(D)J recombination is essential to produce an effective adaptive immune system but since the reaction involves the breakage and rejoining of DNA, it is highly dangerous and errors have long been thought to lead to leukaemias and lymphomas.
  Epigenetics and Cancer: Development of Novel Tools to Determine how Aberrant V(D)J Recombination Reactions Cause Leukaemia
  Dr J Boyes
Applications accepted all year round
V(D)J recombination generates a highly diverse set of immunoglobulin and T cell receptor genes to enable vertebrates to fight a vast range of infections.
  Nanoscale Tweezers for single molecule manipulation
  Dr P Actis
Application Deadline: 4 March 2019
Are you interested in working at the interface between electronic engineering, physics, and biology? Do you want to contribute to the development of the next generation of ultra-sensitive tools for personalized health?.
  Structural biology of membrane proteins
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr C Pliotas
Application Deadline: 15 March 2019
Research in the Pliotas group focuses on the investigation of molecular mechanisms which underlie the structure and function of integral membrane proteins, in particular ion channels and transporters.
  Characterization of bispecific antibodies using structural mass spectrometry and imaging techniques
  Research Group: Astbury Centre for Structural Molecular Biology
  Prof F. Sobott, Prof N A Ranson, Dr J.R. Ault
Application Deadline: 28 February 2019
The majority of drugs currently in development are biotherapeutics, i.e. based on proteins, antibodies or other biomolecules. They promise unsurpassed specificity and selectivity in how they target molecules or structures in the cell, but can also carry cargo to their destination.
  Aldehyde dehydrogenase expression and function in cancer stem cells
  Research Group: Institute of Cancer Therapeutics
  Dr K Pors, Dr A Mardaryev, Prof A Locke
Applications accepted all year round
Aldehyde dehydrogenases (ALDHs) catalyse the oxidation and detoxification of reactive endogenous and exogenous aldehydes into carboxylic acids via NAD+ coupled reduction.
  Health Opportunity for Patient Empowerment in Gestational Diabetes (HOPE-GDM)
  Research Group: Chemistry and Biosciences
  Prof A M Graham, Prof R Qahwaji, Prof A Locke
Applications accepted all year round
Gestational Diabetes is a temporary condition diagnosed at 24-28 weeks gestation, where the body is unable to maintain normal blood glucose levels due to insulin resistance during pregnancy.
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