Molecular Biology PhD Projects, Programmes & Scholarships in Leeds

We have 41 Molecular Biology PhD Projects, Programmes & Scholarships in Leeds

Therapeutic resolution of Myelodysplastic Syndrome (MDS) by natural products

University of Bradford Faculty of Life Sciences

Research Group: Pharmacology and Experimental Therapeutics

Myelodysplastic syndromes (MDS) are a type of blood cancer where the patients do not have enough healthy blood cells. Read more

Supervisors: Dr T Nasim, Dr M Najafzadeh

Year round applications PhD Research Project Self-Funded PhD Students Only

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How effective is 3D reconstructed human skin as an alternative to human skin for permeation studies?

University of Bradford Faculty of Life Sciences

The assessment of percutaneous absorption of molecules is a very important step in the evaluation of any transdermal drug delivery system. Read more

Supervisors: Dr X Liu, Dr M Isreb

Year round applications PhD Research Project Self-Funded PhD Students Only

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Evaluating Photodynamic Therapy in colorectal cancer using patient-derived organoids

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

Colorectal cancer (CRC) is the 3rd most common cancer worldwide. Surgery is first line treatment and often in adjunct with chemotherapy. Read more

Supervisors: Dr MI Khot, Prof A Paradkar, Prof D Jayne

Year round applications PhD Research Project Self-Funded PhD Students Only

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Genetics: Investigating the functional effect of novel genes and genetic variants in malignant hyperthermia susceptibility using model systems

University of Leeds Faculty of Medicine and Health

Malignant hyperthermia (MH) is an inherited condition, where patients exposed to anaesthetic drugs are susceptible to a dramatic hyperthermic and hypermetabolic response that can contribute to a significant proportion of post-operative morbidity and deaths. Read more

Supervisors: Prof P Hopkins, Dr M-A Shaw, Dr C Diggle

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer: Characterization of EGFR signaling activated by the endothelium in the process of breast cancer metastasis to the brain

University of Leeds Faculty of Medicine and Health

The Epidermal Growth Factor Receptor (EGFR) is important in normal physiology regulating epithelial development and homeostasis. In cancer, deregulation resulting from mutation, amplification or transcriptional upregulation promotes tumorigenesis. Read more

Supervisors: Dr G Mavria, Dr S Bell

Year round applications PhD Research Project Self-Funded PhD Students Only

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Oncology: Evaluating Photodynamic Therapy in colorectal cancer using patient-derived organoids

University of Leeds Faculty of Medicine and Health

Colorectal cancer (CRC) is the 3rd most common cancer worldwide. Surgery is first line treatment and often in adjunct with chemotherapy. Read more

Supervisors: Dr I Knot, Prof D Jayne

Year round applications PhD Research Project Self-Funded PhD Students Only

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Translational Medicine: Understanding the mechanism(s) of resistance to EPA to personalise therapy and improve outcome

University of Leeds Faculty of Medicine and Health

Advanced colorectal cancer (CRC) is the UK’s second most lethal cancer, with limited treatment options for unresectable metastatic tumours. Read more

Supervisors: Dr MA Volpato, Prof M Hull

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer Biology: The role of Wnt signaling in glioblastoma therapeutic resistance

University of Leeds Faculty of Medicine and Health

Glioblastoma is a deadly brain tumour treated with surgery, radiotherapy and chemotherapy with patient survival of 6-15 months. Read more

Supervisors: Dr G Mavria, Dr S Bell, Dr C Toomes

Year round applications PhD Research Project Self-Funded PhD Students Only

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Genetics: Unravelling the Norrin/beta-catenin signaling pathway and its role in retinal angiogenesis and blindness

University of Leeds Faculty of Medicine and Health

Our previous work on the genetic analysis of individuals with the inherited retinal disease Familial Exudative Vitreoretinopathy (FEVR), has helped identify a new angiogenesis pathway, the Norrin/beta-catenin pathway. Read more

Supervisors: Dr C Toomes, Dr J Bond, Dr S Bell

Year round applications PhD Research Project Self-Funded PhD Students Only

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