University of the West of Scotland Featured PhD Programmes
Imperial College London Featured PhD Programmes
De Montfort University Featured PhD Programmes

Neuroscience / Neurology PhD Projects, Programs & Scholarships in Leeds

We have 9 Neuroscience / Neurology PhD Projects, Programs & Scholarships in Leeds

Discipline

Discipline

All disciplines

Location

Location

Leeds  United Kingdom

Institution

Institution

All Institutions

PhD Type

PhD Type

All PhD Types

Funding

Funding

All Funding


We have 9 Neuroscience / Neurology PhD Projects, Programs & Scholarships in Leeds

Evaluation of potential therapeutics in a mouse model of KCNT1-related epilepsy

  Research Group: School of Biomedical Sciences
Human mutations in the KCNT1 gene, which encodes a sodium-activated potassium channel, results in severe and drug-resistant childhood epilepsy. Read more

Cell Biology: Exploring the mitotic functions of ASPM in human brain size regulation

The increase in relative brain size is one of the most striking events in human evolution. To determine how human brain size is normally regulated we have investigated the cause of autosomal recessive primary microcephaly (MCPH), a congenital disorder of reduced brain size and associated mental retardation. Read more

Cancer: 3D model of the brain tumour perivascular niche: developing new approaches to target brain tumours

Aggressive brain tumours have dismal outcomes. Patients with glioblastoma multiforme, or brain metastases arising from tumours in other part of the body such as melanoma and breast cancer, have a median survival of only 14 months when treated with surgery followed by radiation and chemotherapy. Read more

Targeting protein acetylation to reduce microglia activation in neurodegenerative disorders

Recently, inhibitors of histone deacetylase enzymes (HDACs) have been identified as having potential therapeutic value for a range of neuronal disorders including Alzheimer’s disease, dementia and stroke [1, 2]. Read more

Neuroinflammation in Alzheimer’s disease: what is the role of amyloid-beta fibril structure?

This project will explore the role of amyloid-beta fibril structure in triggering neuroinflammation in Alzheimer’s disease. Alzheimer’s disease is the most common form of dementia and affects millions worldwide. Read more

Identifying cognitive and biochemical changes underlying lifestyle risk factors for dementia

  Research Group: Pharmacology and Experimental Therapeutics
Dementia describes a group of age-associated conditions of which cognitive decline is a major feature. Alzheimer’s disease (AD) is the most common cause of dementia and is characterised by the onset of a gradual cognitive decline. Read more

Determining brain glycosylation in ageing and Alzheimer’s disease

  Research Group: Pharmacology and Experimental Therapeutics
Increasing age is associated with lower levels of cognitive performance; concomitant with this is a decrease in brain glucose metabolism. Read more

Identifying glucose-dependent mechanisms underlying risk factors for Alzheimer’s disease

  Research Group: Pharmacology and Experimental Therapeutics
Several risk factors for Alzheimer’s disease including diabetes and midlife obesity are age-dependent and have an obvious metabolic component resulting in impaired glucose metabolism. Read more
  • 1

Filtering Results