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Neuroscience / Neurology PhD Projects, Programs & Scholarships in Leeds

We have 10 Neuroscience / Neurology PhD Projects, Programs & Scholarships in Leeds

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  Using massively-paralleled sequencing to find the cause of inherited conditions that affect the front of the eye
  Dr M Ali, Prof C Inglehearn
Applications accepted all year round
Eye diseases are a common cause of human disability and many of them are inherited. These include congenital as well as adult-onset conditions and diseases of ageing, and may involve abnormalities at the back of the eye or the anterior eye structures.
  Stimulation paradigms for recovery of movement after spinal cord injury
  Research Group: School of Biomedical Sciences
  Dr S.L. Astill, Dr S Chakrabarty, Dr M Sivan
Application Deadline: 11 March 2019
Despite advances in medical care and rehabilitation, the recovery of arm and hand function following a cervical spinal cord injury (cSCI) is often limited…
  An integrated approach to the study of cellular interactions with amyloid
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr E W Hewitt, Prof S E Radford
Applications accepted all year round
The formation of insoluble amyloid fibrils is associated with a spectrum of human disorders, the amyloidoses, which include Alzheimer’s, Parkinson’s, type 2 diabetes and dialysis related amyloidosis (DRA).
  Novel regulators of +TIP localisation and function
  Dr E E Morrison, Dr S Bell, Dr J Bond
Applications accepted all year round
Microtubules (MTs) are a key cytoskeletal network in all eukaryotic cells. MTs grow and shrink primarily through the addition or loss of tubulin heterodimers from their plus end.
  The genetic basis of cognitive impairment in intellectual disability and schizophrenia
  Prof C Inglehearn, Dr M Ali
Applications accepted all year round
Schizophrenia is a chronic mental health condition affecting 1% of human populations, with symptoms that include visual and auditory hallucinations, delusions and disordered thought, leading to disruption of the sense of self.
  Genome and transcriptome sequencing and functional analysis to find new mutation types in patients with inherited blindness
  Prof C Inglehearn
Applications accepted all year round
Human inherited retinal dystrophies (IRDs) result from mutations in over 200 different genes, many of them first implicated by the Leeds Vision Research Group (eg Panagiotou E et al 2017, AJHG 100:960-968; El-Asrag M et al 2015, 96:948-54).
  Novel GABAergic mechanisms modulating nociception and pain
  Research Group: School of Biomedical Sciences
  Prof N Gamper, Dr J. Johnston
Application Deadline: 1 March 2019
Pathological pain is a vast and unmet clinical problem which brings about poor quality of life for sufferers and puts a colossal burden on healthcare systems worldwide.
  Identifying glucose-dependent mechanisms underlying risk factors for Alzheimer’s disease
  Research Group: Pharmacology and Experimental Therapeutics
  Dr R Williamson, Dr S McLean
Applications accepted all year round
Several risk factors for Alzheimer’s disease including diabetes and midlife obesity are age-dependent and have an obvious metabolic component resulting in impaired glucose metabolism.
  Determining brain glycosylation in ageing and Alzheimer’s disease
  Research Group: Pharmacology and Experimental Therapeutics
  Dr R Williamson, Dr C Sutton
Applications accepted all year round
Increasing age is associated with lower levels of cognitive performance; concomitant with this is a decrease in brain glucose metabolism.
  Development and characterisation of synthetic ion channel binding proteins.
  Research Group: School of Biomedical Sciences
  Dr J D Lippiat, Dr D Tomlinson
Applications accepted all year round
We are developing methods to identify novel proteins, Affimers, that recognise extracellular domains of ion channels. These have applications in various aspects of biology, from tools to visualise the location and distribution of ion channels in native tissue, to novel modulators of ion channel function.
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