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Pathology PhD Projects, Programs & Scholarships in Leeds

We have 12 Pathology PhD Projects, Programs & Scholarships in Leeds

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  Polymers for treating amoebic infections in India
  Research Group: Chemistry and Biosciences
  Prof S Rimmer, Dr W Martin
Applications accepted all year round

Funding Type

PhD Type

Amoebic parasitic infections are widespread in the tropics. Amoebic dysentery can be fatal if the parasite progresses to the brain.
  The role of UV exposure and novel compounds on the immunogenicity and genotoxicity of skin cancer
  Research Group: Chemistry and Biosciences
  Dr M Najafzadeh, Dr S Kauser
Applications accepted all year round

Funding Type

PhD Type

The major aims of this project are to investigate the effect of UV in the development of different skin cancers compared to spontaneously regressing precancerous lesion, keratoacanthoma; and the effect of a novel compounds such as the structurally modified retinoic acid in the treatment of skin cancers and other cutaneous lesions.
  Oncogenic reprogramming of immune cells, a novel mechanism of drug-resistance.
  Dr P Laslo
Applications accepted all year round

Funding Type

PhD Type

Under pathogenic challenges, cells of the innate system become epigenetically reprogrammed and establish immune memory.
  Metabolic reprogramming in cancer: starving tumors of essential nutrients to promote cell death
  Dr S Papa
Applications accepted all year round

Funding Type

PhD Type

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow.
  Nanoinjection: a single molecule technique to study amyloid toxicity in neurons
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr E W Hewitt, Prof S E Radford, Dr P Actis
Applications accepted all year round

Funding Type

PhD Type

Interested in amyloid disorders such as Parkinson’s and Huntington’s. Want to work with cutting edge technology in a multidisciplinary team.
  TRPM2 channel mechanism of neuroinflammation and neurodegeneration in Alzheimer’s disease
  Research Group: School of Biomedical Sciences
  Dr L H Jiang, Dr I Wood
Applications accepted all year round

Funding Type

PhD Type

Alzheimer’s disease (AD) is the most common cause of dementia and also a major cause of morbidity and mortality. Currently, there is no effective therapeutics to treat or slow the disease progress.
  How human teeth form and how that process fails in the inherited condition amelogenesis imperfecta
  Prof C Inglehearn
Applications accepted all year round

Funding Type

PhD Type

Amelogenesis is the process of enamel formation and is essential for the development of functional teeth. Amelogenesis imperfecta (AI) is a failure of that process.
  Genome and transcriptome sequencing and functional analysis to find new mutation types in patients with inherited blindness
  Prof C Inglehearn
Applications accepted all year round

Funding Type

PhD Type

Human inherited retinal dystrophies (IRDs) result from mutations in over 200 different genes, many of them first implicated by the Leeds Vision Research Group (eg Panagiotou E et al 2017, AJHG 100:960-968; El-Asrag M et al 2015, 96:948-54).
  Gastroesophageal reflux in respiratory disease: pathogenic role and improved management
  Prof L Houghton
Applications accepted all year round

Funding Type

PhD Type

Gastroesophageal reflux (GER) is associated with many lung diseases, including but not limited to idiopathic pulmonary fibrosis (IPF), non-IPF interstitial lung disease (ILD), chronic obstructive pulmonary disease (COPD), cystic fibrosis (CF), non-CF bronchiectasis, asthma and idiopathic chronic cough.
  The functional characterization of the tumour suppressor gene CSMD1 in breast cancer
  Dr S Bell
Applications accepted all year round

Funding Type

PhD Type

CUB and Sushi multiple domains protein 1 (CSMD1) maps to 8p23, a region deleted in many cancers including breast cancer. Our previous work has established that CSMD1 is an independent prognostic marker in ductal breast cancer, with reduced expression associated with high tumour grade and poor survival1.
  Identification and functional characterisation of BRIT1/MCPH1 synthetic lethal genes to treat breast and ovarian cancer
  Dr S Bell, Prof C A Johnson
Applications accepted all year round

Funding Type

PhD Type

Women who have undergone surgery for breast and ovarian cancer often have additional chemotherapy to kill residual cancer cells and prevent recurrence.
  International PhD Academy: Medical Research

Funding Type

PhD Type

Our vision is to impact locally, nationally and globally on biomedical and clinical research with a primary emphasis on health outcomes.
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