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Pharmacy / Pharmaceutics PhD Projects, Programs & Scholarships in Leeds

We have 21 Pharmacy / Pharmaceutics PhD Projects, Programs & Scholarships in Leeds

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Showing 11 to 20 of 21
  Therapeutic resolution of pulmonary arterial hypertension (PAH) by natural products
  Research Group: Pharmacology and Experimental Therapeutics
  Dr T Nasim, Prof C Wright
Applications accepted all year round

Funding Type

PhD Type

Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death.
  Tetrazines as Traceless Carriers for Polar Drugs
  Research Group: Medicines Development and Pharmaceutical Sciences
  Dr R Wheelhouse, Prof P Loadman
Applications accepted all year round

Funding Type

PhD Type

A recent invention in Bradford has identified a new carrier molecule that reduces the polarity of polar drugs.
  Studies on impact of co-former selection on physicochemical properties of crystalline active pharmaceutical complexes
  Research Group: Medicines Development and Pharmaceutical Sciences
  Dr K Paluch
Applications accepted all year round

Funding Type

PhD Type

Studies on the enhanced bioavailability profile of existing antibiotics are essential, considering growing bacterial resistance and increasing demand on cost-effective and safe antibacterial treatments.
  Quantitative structure/skin-permeation relationships (QSPeRs); an investigation of the relevance of parameters determined with biomembrane-mimicking systems for the predictability of drug partitioning into skin
  Research Group: Medicines Development and Pharmaceutical Sciences
  Dr X Liu, Prof D J Tobin
Applications accepted all year round

Funding Type

PhD Type

The transdermal route has many advantages over other routes for the delivery of drugs with systemic activity. These include the ease of use (and withdrawal in the occurrence of side-effects), avoidance of first-pass metabolism, and improved patient compliance.
  Activity based proteomic probes for profiling CYP2W1 in cancer tissues
  Research Group: Institute of Cancer Therapeutics
  Dr C Sutton, Dr K Pors
Applications accepted all year round

Funding Type

PhD Type

Cytochromes P450 (CYPs) are a superfamily of mixed function oxidases of which CYP1-4 subfamily members are unique in their ability to oxidise drugs.
  Exploration of 5-fluorouracil resistance mechanisms in colorectal cancer using 5-FU-resistant xenograft models
  Research Group: Institute of Cancer Therapeutics
  Dr S Shnyder, Dr C Sutton
Applications accepted all year round

Funding Type

PhD Type

Despite therapeutic advances, colorectal cancer (CRC) still has a 45% mortality rate, and one of the major problems is the development of acquired resistance to treatment with anticancer drugs.
  Ion channel gating kinetics and structure implication for drug delivery
  Research Group: Chemistry and Biosciences
  Dr L Shang, Dr Z Hughes
Applications accepted all year round

Funding Type

PhD Type

Ion channels are proteins which sit in the membrane of every cell in the body and control the flow of positively charged ions such as sodium and potassium into and out of the cell.
  Biodegradable composite materials (Bio-PolyMOFs) for applications in targeted delivery of drugs to improve healthcare and reduce antimicrobial resistance in developing countries and worldwide
  Research Group: Chemistry and Biosciences
  Dr S Nayak, Dr A L Kelly, Dr M Katsikogianni
Applications accepted all year round

Funding Type

PhD Type

Growing antimicrobial resistance (AMR) is one of the major global challenges and is linked to the use of unnecessarily high doses of orally administered antibiotics following medical surgery and infections.
  Investigating the mechanism of action of dual antiangiogenic/ antineoplastic drugs using organotypic co-culture of fibroblasts and endothelial cells
  Research Group: Institute of Cancer Therapeutics
  Dr J Elies Gomez, Dr K Pors
Applications accepted all year round

Funding Type

PhD Type

An important feature of many types of cancer is the ability to develop abnormal angiogenesis (blood vessel formation); this allows cancer cells to gain access to nutrients and favours metastasis.
  Therapeutic resolution of Myodysplastic Syndrome (MDS)
  Research Group: Pharmacology and Experimental Therapeutics
  Dr T Nasim, Dr K Pors
Applications accepted all year round

Funding Type

PhD Type

Myelodysplastic syndromes (MDS) are the most common adult myeloid malignancy in the UK and it has been estimated that around 8,000 and 40,000 new cases are diagnosed each year in the UK and USA, respectively.
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