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We have 7 Structural Biology PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Leeds
Structural Biology PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Leeds
We have 7 Structural Biology PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Leeds
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Understanding the structural consequences of ribosome specialisation
Protein synthesis by ribosomes (translation) and its regulation is essential to life. While it has been traditionally thought that ribosomes were not involved in the regulation of translation, it is now becoming clear that they do contribute. Read more
Control and inhibition of virus replication
The Tuplin laboratory utilises a range of cutting-edge approaches to investigate how arboviruses - specifically Chikungunya, Dengue and Zika viruses - control replication and translation of their genomes through interactions between RNA structures, host cell proteins and non-coding RNA, and the potential of such RNA elements/interactions as novel therapeutic targets. Read more
Alpha-synuclein amyloid in Parkinson's disease: using Nanoinjection as a tool to study alpha-synuclein amyloid toxicity inside neurons
Intraneuronal inclusions known as Lewy bodies are a hallmark of Parkinson’s disease. Amyloid fibrils formed by the misfolding of alpha-synuclein are the principal component of Lewy Bodies. Read more
Epigenetics and Cancer: Determining how Mistakes in V(D)J Recombination Trigger Leukaemias and Lymphomas
Research Group:
School of Molecular and Cellular Biology
V(D)J recombination is essential to produce an effective adaptive immune system but since the reaction involves the breakage and rejoining of DNA, it is highly dangerous and errors have long been thought to lead to leukaemias and lymphomas. Read more
Cryo-electron microscopy of influenza virus and bunyaviruses
As demonstrated by SARS-CoV-2, viruses have the potential to cause devastating economic and healthcare disruption on a global scale. Read more
Pushing the Resolution Limits of High-Speed Atomic Force Microscopy
Research Group:
School of Physics and Astronomy
Understanding the structural dynamics of complex molecules is vital to advancing our knowledge of materials, medicine and diseases, yet there are few techniques which can capture motions at high enough speeds or resolution to understand the underlying behaviour. Read more
Virology: Unique Antiviral Therapy targeting Zika and Related Viruses
Zika Virus (ZIKV) has emerged as a new mosquito-borne threat to public health after the devastating South American outbreak. Read more
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