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We have 16 Biochemistry PhD Projects, Programmes & Scholarships in Leicester
Biochemistry PhD Projects, Programmes & Scholarships in Leicester
We have 16 Biochemistry PhD Projects, Programmes & Scholarships in Leicester
Join Our Quest to Unravel the Secrets of Eukaryotic Genomes!
We're on the lookout for passionate PhD students who are eager to delve deep into the mysteries of our DNA. Our quest? To understand the subtle changes that determine how our genes function, both in sickness and in health. Read more
Obtaining an integrated understanding of oncogenic RAS signalling
The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. The physiological importance of RAS signalling is evident as about 25% of all human cancers harbour mutations in ras genes, where kras is most frequently mutated (about 18%) (COSMIC, v94). Read more
How do RNA-binding proteins control splice site selection? A multi-disciplinary approach
Almost every protein-coding gene in vertebrates can and does express multiple proteins. This is achieved primarily by RNA splicing, which is an essential step in gene expression in mammals and generates incredible diversity. Read more
Waste-derived bioplastics for a circular and sustainable food packaging economy (Ref: AACME-24-036)
Food packaging plays an essential role in containing, portioning and protecting food products against contamination, reducing food waste and associated emissions. Read more
Developing Natural Surfactants from Biomass for Industrial Applications (Ref: AACME-24-019)
The Department of Chemical Engineering at Loughborough University is seeking a motivated PhD candidate to join our team in exploring the extraction and development of natural surfactants from biomass for use in various industries, particularly cosmetics. Read more
Structural investigation of oncogenic splicing factors
More than 90% of human genes can and do express multiple proteins. This is achieved by a process called alternative RNA splicing, which is an essential step in gene expression in mammals. Read more
Understanding gene regulation by HDAC1 complexes in development and cancer
Packaging DNA into nucleosomes helps protect the long fragile genomes of eukaryotic species. However, in doing so it becomes an ever-present physical barrier to the machinery required for its replication, repair and transcription. Read more
Crystallisation with 3D printing template and hydrogel templates (Ref: AACME-24-003)
This PhD project aims to develop innovative methods for the crystallisation of various compounds, including small organic molecules for pharmaceutical manufacturing, inorganic compounds, such as for battery recycling and water treatment, macromolecules (such as proteins, viruses, etc.) for food and biopharmaceutical bioseparation. Read more
The role of Reactive Sulfur Species in Ageing and Disease
Oxidative stress (OS) is a major driver of cellular dysfunction in ageing and disease. Read more
Redefining DNA-double strand break repair in humans
Numerous DNA damaging agents constantly cause damage to cellular DNA. Read more
Biomarkers Associated with motor Neurone Disease and Dementia development after concussion in Females and Males: BANDD.
Highlights. This will be an exciting opportunity to explore the differences between male and female brains responses to trauma in sport. Read more
Structural and functional characterisation of MALT1 ubiquitination to aid in the development of novel anti-cancer therapies
Nuclear factor-kappa B (NF-kB) is a family of transcription factors that play a crucial role in regulating various cellular processes; primarily related to immune responses, inflammation, and cell survival. Read more
Structural insights into genome control by cohesin
Our basic goal is to understand how chromatin structure influences gene regulation. Chromatin is generally repressive in nature but its structure is manipulated by cells in a regulated way to determine which genes are potentially transcriptionally active and which genes remain repressed in a given cell type. Read more
Structural and functional analysis of the protein complexes which regulate cell fate decisions to identify novel cancer therapies
Whether a cell dies or not has profound consequences on health and disease. In healthy tissue, cells that acquire high levels of genetic damage are safely removed via a process of programmed cell death. Read more
Targeting senescence to ameliorate ageing and treat cancer and other age-related diseases
Ageing is a biological process that affects all humans. Despite the scientific advances of the past decades, the mechanisms that lead to ageing are not fully understood. Read more
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