New ways to look at enzyme structures
Dr P C E Moody, Dr J Basran
5 May 2019
Metal-catalysed activation of oxygen in biology is achieved using either copper or iron. In the case of iron, this includes the heme-containing enzymes which activate oxygen.
Exploring the boundaries of the human acetylome
Dr S Cowley, Prof D Panne
5 May 2019
Lysine acetylation (Lys-Ac) is an abundant post-translational modification (PTM) occurring on thousands of proteins. However, our understanding of ‘acetylome’ regulation and its functional consequences remains well behind other common PTMs such as phosphorylation and ubiquitination.
Development of Methods for Evaluating Use of Targeted Tests in Emergency Medicine
Dr R Owen, Prof T Coats, Dr M Sweeting
3 April 2019
Over the last 10 years within emergency and acute care there has been a rapid movement towards ‘near patient’ testing and early investigation with the presumption that earlier investigation will give rise to early decision making and hence reduced length of stay in hospital and better outcomes.