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Bioinformatics PhD Projects, Programs & Scholarships in Leicester

We have 17 Bioinformatics PhD Projects, Programs & Scholarships in Leicester

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Showing 1 to 10 of 17
  Clock gene polymorphisms in Drosophila; natural selection and function
  Prof C P Kyriacou, Dr E Rosato
Application Deadline: 5 May 2019
The molecular function of circadian clock genes are well understood and conserved from flies to mammals, but the implications of natural variation in clock gene sequences are only recently becoming evident.
  New ways to look at enzyme structures
  Dr P C E Moody, Dr J Basran
Application Deadline: 5 May 2019
Metal-catalysed activation of oxygen in biology is achieved using either copper or iron. In the case of iron, this includes the heme-containing enzymes which activate oxygen.
  Exploring the boundaries of the human acetylome
  Dr S Cowley, Prof D Panne
Application Deadline: 5 May 2019
Lysine acetylation (Lys-Ac) is an abundant post-translational modification (PTM) occurring on thousands of proteins. However, our understanding of ‘acetylome’ regulation and its functional consequences remains well behind other common PTMs such as phosphorylation and ubiquitination.
  Network interactions shape the circadian clock in Drosophila melanogaster
  Dr E Rosato, Prof C P Kyriacou
Application Deadline: 5 May 2019
The circadian clock is an endogenous mechanism that synchronizes almost all behaviour and physiology with the Earth’s 24 hour environmental cycles.
  Investigating novel treatments for sepsis by understanding the pathogenesis of invasive infection
  Prof M Oggioni, Dr C D Bayliss
Application Deadline: 5 May 2019
We have recently discovered that bacteria, previously considered extracellular pathogens replicate within a subset of macrophages before causing invasive infection (Ercoli et al., Nature Microbiology 2018).
  Application of molecular imprinted polymer nanoparticles for surface proteomics
  Dr E Piletska, Dr S Macip
Application Deadline: 25 April 2019
Surface proteins are very important targets for diagnostic and therapeutic applications as they participate in major cellular functions and inter-cellular communication.
  Evaluating use of national databases of routinely collected data as an alternative to direct patient contact for clinical trial design, follow-up & generalisability
  Dr W Toff, Prof K Abrams, Prof L Gray
Application Deadline: 3 April 2019
The UK TAVI trial is an ongoing multi-centre randomised controlled trial to assess the clinical effectiveness and cost-utility of TAVI, compared with conventional surgical aortic valve replacement, in patients with severe symptomatic aortic stenosis, who are at intermediate or high operative risk.
  Complex synthesis of multi-component interventions studies impacting on multiple outcome measures: Optimisation of packages of care for preventing childhood accidents in the home
  Prof A Sutton, Dr N Cooper
Application Deadline: 3 April 2019
There is increasing interest and use of ‘complex’ interventions - which include multiple components - in many areas of health research (Higgin et al.).
  Identification of movement patterns indicative of frailty and pre-frailty using wearable activity monitors
  Dr A Rowlands, Dr T Yates, Dr M Bocian, Prof S Conroy
Application Deadline: 3 April 2019
The PhD student will work within the Diabetes Research Centre (DRC) and the dedicated Health Data Research UK facility. The DRC is one of the leading diabetes research centres internationally, also hosting the lifestyle theme of the NIHR Leicester Biomedical Research Centre.
  Development of Methods for Evaluating Use of Targeted Tests in Emergency Medicine
  Dr R Owen, Prof T Coats, Dr M Sweeting
Application Deadline: 3 April 2019
Over the last 10 years within emergency and acute care there has been a rapid movement towards ‘near patient’ testing and early investigation with the presumption that earlier investigation will give rise to early decision making and hence reduced length of stay in hospital and better outcomes.
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