This project will focus on various aspects of the biology of aging and extending healthspan, including but not limited to cellular metabolic pathways that confer resilience to aging. Read more
The global population is aging at an unprecedented rate, leading to a surge in neurodegenerative conditions such as Alzheimer's and vascular dementia. Read more
Cerebral Haemodynamics in Ageing and Stroke Medicine (CHiASM) Research Group of the Department of Cardiovascular Sciences has an international reputation for leading research on cerebral haemodynamic alterations resulting from ischaemic and/or haemorrhagic stroke. Read more
Chronic kidney disease (CKD) is a major public health emergency. 7 million people in the UK have CKD, numbers are expected to increase over the next 10 years, with a major impact on the UK health economy (1). Read more
Although plenty of cancer research is in the field of cancer cell biology, there is lack of knowledge that can cascade the biological theory to those measurable parameters that can be obtained non-destructive and in real-time at clinical level, i.e. Read more
In all kingdoms of life, DNA damaging agents can jeopardize the integrity of the cellular genome, resulting in a range of developmental defects. Read more
This project will help understand why organisms age differently by establishing the effect of early life environments on epigenetic ageing in the model insect, Nasonia vitripennis. Read more
Radiotherapy is used to treat more than 50% of cancer patients, but up to a quarter of patients suffer side effects that can affect their quality of life in the long-term. Read more
Antibiotic resistance (AbR) in bacteria has become a global health emergency. Just in 2019 alone, AbR has caused 1.27 million deaths and was associated indirectly with other 4.95 million deaths1. Read more
Malignant pleural mesothelioma is a rare, incurable cancer that carries a dismal prognosis. Its incidence is increasing globally despite its primary cause, asbestos exposure, having been known for over 50 years. Read more
Birds of prey have suffered persecution for centuries through trapping, shooting, poisoning and theft from the wild to meet the demand from egg collectors and falconers; they were also amongst the earliest beneficiaries of DNA testing in wildlife forensics. Read more
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