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Cell Biology / Development PhD Projects, Programs & Scholarships in Leicester

We have 11 Cell Biology / Development PhD Projects, Programs & Scholarships in Leicester

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  Understanding microtubule-actin crosstalk in neuronal cell migration
  Prof A M Fry, Prof I D Forsythe
Application Deadline: 7 June 2020

Funding Type

PhD Type

Summary. This BBSRC-funded 4-year PhD studentship will address the mechanism of action of a microtubule-associated protein, EML4, in promoting microtubule-actin crosstalk and neuronal cell migration [1].
  Obtaining mechanistic insights into interplay of multiple effectors of oncogenic RAS molecules
  Dr K Tanaka, Dr A Revyakin
Application Deadline: 7 June 2020

Funding Type

PhD Type

The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. Importantly, about 20% of all human cancers harbour mutations in RAS genes (COSMIC).
  Cryo-Electron Microscopy of Histone Deacetylase Complexes
  Prof J Schwabe, Dr S Cowley
Application Deadline: 7 June 2020

Funding Type

PhD Type

Histone deacetylase complexes play a role in many cellular processes, such as cancer, cell cycle progression and DNA repair. Investigating how these HDAC complexes act to control gene expression and their interactions with other proteins should lead to an understanding of their influence in the cell.
  Molecular Modelling of P2X receptor agonism and antagonism
  Dr R Schmid
Application Deadline: 7 June 2020

Funding Type

PhD Type

P2X receptors (P2XRs) form a family of ligand-gated ion channels activated upon binding of extracellular ATP (for review see [1]).
  Revealing molecular mechanisms of gene silencing
  Dr T Schalch, Dr S Cowley
Application Deadline: 7 June 2020

Funding Type

PhD Type

Regulation of transcription through chromatin architecture is governed by nucleosome remodelers and chromatin modifying complexes.
  Structural mechanism of signal-dependent gene transcription
  Prof D Panne, Dr A Revyakin
Application Deadline: 7 June 2020

Funding Type

PhD Type

PhD Start date. September 2020. The control of gene transcription is the main regulatory step for cellular gene regulation.
  Structural, kinetic and functional characterisation of ion channel function in the gal-3-fibrosome
  Prof B Gooptu, Prof G Vuister
Application Deadline: 7 June 2020

Funding Type

PhD Type

4 Year PhD Studentship available to start September 2020. Fibrosis is a common ageing-associated process that affects all organs.
  The evolution of the neurogenic gene regulatory networks in Bilateria
  Dr R FEUDA, Dr E Rosato
Application Deadline: 7 June 2020

Funding Type

PhD Type

The evolution of the nervous system is one of the most important innovations in the evolutionary history of animals. Because neurons are present in deuterostome (e.g.
  Discovery and modelling of common molecular mechanisms disrupting hearing in genetic mutations associated with hearing loss
  Prof I D Forsythe, Dr A Lecchini-Visintini
Application Deadline: 7 June 2020

Funding Type

PhD Type

Objectives. Determine the cellular and molecular changes in the auditory brainstem of mice carrying genetic mutations associated with hearing loss and language development and use modelling to evaluate common mechanisms.
  Application of advanced spectroscopic techniques to monitor real-time transformations in aerosolized bovine tuberculosis bacteria
  Dr N Garton, Dr A Hudson
Application Deadline: 7 June 2020

Funding Type

PhD Type

Mycobacterium bovis is the causative agent of bovine tuberculosis (bTB), a devastating disease affecting global cattle populations.
  Midlands Integrative Biosciences Training Partnership (MIBTP) Funded PhD Studentships

Funding Type

PhD Type

The Midlands Integrative Biosciences Training Partnership (MIBTP) is a BBSRC-funded doctoral training partnership between five research-intensive universities, the University of Warwick, the University of Birmingham, the University of Leicester, Aston University, and Harper Adams University.
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