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Cell Biology / Development PhD Projects, Programs & Scholarships in Leicester

We have 10 Cell Biology / Development PhD Projects, Programs & Scholarships in Leicester

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  Development and Optimisation of a Biohybrid Heart Assist Device
  Prof S Korossis
Application Deadline: 28 January 2019
Reference number. WS19. Start date of studentship. 1st October 2019. Closing date of advert. 28th January 2019. Interview date. TBC.
  Developing precision medicines for B-cell leukaemias and lymphomas
  Dr S Macip, Prof M J S Dyer
Applications accepted all year round
In this project, we propose to look for novel therapies for B-cell leukaemias and lymphomas in a translational and mechanistic fashion.
  Targeting senescence to ameliorate ageing and treat cancer and other diseases
  Dr S Macip
Applications accepted all year round
Ageing is a biological process that affects all living creatures. Despite the scientific advances of the past decades, the mechanisms that lead to ageing in humans are not fully understood.
  The role of fibroblasts in skeletal muscle ageing (SSEHS/NM)
  Dr N Martin
Applications accepted all year round
Loughborough University is a top-ten rated university in England for research intensity (REF2014) and an outstanding 66% of the work of Loughborough’s academic staff who were eligible to be submitted to the REF was judged as ‘world-leading’ or ‘internationally excellent’, compared to a national average figure of 43%.
  Using state-of-the-art proteomics to study the cellular and extracellular protein composition in human kidney disease; identification of novel biomarkers and bioactive drug targets in IgA Nephropathy
  Dr A Didangelos, Prof J Barratt
Applications accepted all year round
One of the key pathological characteristics of IgA nephropathy (IgAN) is the maladaptive and chronic accumulation and remodelling of the extracellular matrix (ECM) in affected glomeruli leading to fibrosis and progressive loss of function.
  Investigating the effect of telomere length on endothelial cell function
  Dr V Codd, Prof NJ Samani
Application Deadline: 27 January 2019
Telomeres are protein bound DNA repeat structures at the ends of eukaryotic chromosomes, Telomere length (TL) has been proposed as a marker of biological ageing and shorter TL associates with several age related diseases, including coronary artery disease (CAD).
  The genetic contribution of biological age differences in disease risk
  Dr C Nelson, Prof F Dudbridge, Dr V Codd
Application Deadline: 27 January 2019
Telomere length (TL) is reflective of cellular age, shortens over time and is proposed as a marker of biological age. Here in Leicester we are measuring mean Leucocyte Telomere Length (LTL) in all 500,000 individuals participating in UK Biobank, these exciting data will be used for this project.
  Understanding the role of endothelin pathway genetic variants in coronary artery disease
  Dr T Webb, Prof S Ye, Dr C Nelson
Application Deadline: 27 January 2019
Coronary artery disease (CAD), which leads to angina and heart attacks, is caused by a combination of genetic and lifestyle factors.
  Identification of novel genes and addressing the missing heritability in albinism
  Dr M Thomas, Prof I Gottlob, Prof Y Zhang
Application Deadline: 21 January 2019
Albinism is a genetically heterogeneous group of congenital hypomelanotic disorders. It is characterized by ocular features such as infantile nystagmus, iris transillumination, foveal hypoplasia, chorioretinal hypopigmentation, photophobia and axonal misrouting at the optic chiasm.
  PhD in Neuroscience - Study of memory coding with single cell recordings in humans
  Prof R Quian Quiroga
Application Deadline: 1 March 2019
Fully Funded PhD Studentship (for UK/EU candidates only) Centre for Systems Neuroscience, University of Leicester, UK. www.le.ac.uk/csn.
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