The role of fibroblasts in skeletal muscle ageing (SSEHS/NM)
Dr N Martin
Applications accepted all year round
Loughborough University is a top-ten rated university in England for research intensity (REF2014) and an outstanding 66% of the work of Loughborough’s academic staff who were eligible to be submitted to the REF was judged as ‘world-leading’ or ‘internationally excellent’, compared to a national average figure of 43%.
Investigating the effect of telomere length on endothelial cell function
Dr V Codd, Prof NJ Samani
27 January 2019
Telomeres are protein bound DNA repeat structures at the ends of eukaryotic chromosomes, Telomere length (TL) has been proposed as a marker of biological ageing and shorter TL associates with several age related diseases, including coronary artery disease (CAD).
The genetic contribution of biological age differences in disease risk
Dr C Nelson, Prof F Dudbridge, Dr V Codd
27 January 2019
Telomere length (TL) is reflective of cellular age, shortens over time and is proposed as a marker of biological age. Here in Leicester we are measuring mean Leucocyte Telomere Length (LTL) in all 500,000 individuals participating in UK Biobank, these exciting data will be used for this project.
Identification of novel genes and addressing the missing heritability in albinism
Dr M Thomas, Prof I Gottlob, Prof Y Zhang
21 January 2019
Albinism is a genetically heterogeneous group of congenital hypomelanotic disorders. It is characterized by ocular features such as infantile nystagmus, iris transillumination, foveal hypoplasia, chorioretinal hypopigmentation, photophobia and axonal misrouting at the optic chiasm.