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Genetics PhD Projects, Programs & Scholarships in Leicester

We have 15 Genetics PhD Projects, Programs & Scholarships in Leicester

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  Harnessing large-scale genomic sequencing data to understand smoking behaviour
  Dr C Batini
Applications accepted all year round
In 2018 it has been announced that both whole exome sequences and whole genome sequences will be analysed in the 500K individuals in UK Biobank over the next two to five years.
  Genetic variants associated with multiple diseases
  Prof M Tobin
Applications accepted all year round
As increasing numbers of genetic associations are discovered, it is becoming clear that some genetic variants are associated with more than one or human phenotype (including disease phenotypes).
  Exploring the pathogenic roles of Rab GTPases in models of taupathy
  Prof F Giorgini, Prof C P Kyriacou
Application Deadline: 28 January 2019
Alzheimer’s disease (AD) is the most common neurodegenerative disorder and the predominant cause of dementia. The main pathological hallmarks of the disease in the brain are the presence of amyloid plaques and neurofibrilliary tangles composed of hyperphosphorylated forms of tau (P-tau).
  Evolutionary responses of Daphnia spp. to biophysical disruption in tropical lake systems
  Dr D Ryves, Prof J Anderson, Dr L Orsini, Dr S Mills
Application Deadline: 21 January 2019
Loughborough University is a top-ten rated university in England for research intensity (REF2014). In choosing Loughborough for your research, you’ll work alongside academics who are leaders in their field.
  Transcriptional Control of Stem Cell Differentiation
  Research Group: Gene Expression
  Dr S Cowley
Applications accepted all year round
The ability to regulate the transcriptional activity of protein coding genes is one of the most fundamental processes of life. The transcriptional potential of a gene is directly related to its chromatin context, which in turn, is influenced by the covalent modification of its core histone components.
  The mechanism and intervention of acute renal injury
  Dr B Yang, Prof N J Brunskill
Applications accepted all year round
The Kidney Lifestyle research team run a broad translational research into Acute kidney injury (AKI). This has high mortality with 13 million incidences globally contributing to 1.7 million deaths every year.
  Biomarkers of Coronary Artery Disease in multi-ethnic populations
  Prof D Jones, Prof NJ Samani, Prof G McCann
Application Deadline: 27 January 2019
Coronary artery disease (CAD) is a serious and prevalent cardiovascular disease which can present in patients in many ways. Notably, it has a higher prevalence in the South Asian population.
  Investigating the effect of telomere length on endothelial cell function
  Dr V Codd, Prof NJ Samani
Application Deadline: 27 January 2019
Telomeres are protein bound DNA repeat structures at the ends of eukaryotic chromosomes, Telomere length (TL) has been proposed as a marker of biological ageing and shorter TL associates with several age related diseases, including coronary artery disease (CAD).
  The genetic contribution of biological age differences in disease risk
  Dr C Nelson, Prof F Dudbridge, Dr V Codd
Application Deadline: 27 January 2019
Telomere length (TL) is reflective of cellular age, shortens over time and is proposed as a marker of biological age. Here in Leicester we are measuring mean Leucocyte Telomere Length (LTL) in all 500,000 individuals participating in UK Biobank, these exciting data will be used for this project.
  Understanding the role of endothelin pathway genetic variants in coronary artery disease
  Dr T Webb, Prof S Ye, Dr C Nelson
Application Deadline: 27 January 2019
Coronary artery disease (CAD), which leads to angina and heart attacks, is caused by a combination of genetic and lifestyle factors.
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