Molecular Biology PhD Projects, Programmes & Scholarships for UK Students in Leicester

We have 10 Molecular Biology PhD Projects, Programmes & Scholarships for UK Students in Leicester

Epigenetics of early human development: From molecular mechanisms to regenerative medicine

University of Leicester Molecular and Cell Biology

Ever wondered how nature maintains balance of gene expression between sex chromosomes? Well, the 46th chromosome of XX females, the second X, has to be switched off. Read more

Supervisors: Dr Y Markaki, Dr T Schalch

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Molecular dissection of horizontal gene transfer mechanisms in mycobacteria

University of Leicester Molecular and Cell Biology

A fully funded PhD position is available within the lab of Dr Abhinav KV at Leicester Institute of Structural and Chemical Biology (LISCB), University of Leicester, UK to carry out structural studies on large macromolecular machines that undertake horizontal gene transfer (HGT) in mycobacteria. Read more

Supervisors: Dr A Koyamangalath Vadakkepat , Prof J Schwabe

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Chemical energy conversion in biology studied using advanced spectroscopic and structural tools

University of Leicester Department of Chemistry

Redox properties of metal-containing active sites are critically important to many biocatalytic processes. one third of all proteins contain a redox-active metal, and ca 22% of submissions to the Protein Data Bank contain a transition metal. Read more

Supervisors: Dr PA Ash, Dr H Kwon

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Natural products in bacterial physiology and chemical interaction

University of Leicester Department of Genetics and Genome Biology

Microbial natural products have diverse chemical structures and bioactivities, which range from cell-cell signalling, nutrient acquisition, antifungal and antibacterial activity to stress resistance (1). Read more

Supervisors: Dr C Jenul, Prof D Jones

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Short and long-term genetic and behavioural consequences of traumatic brain injury in fruit flies

University of Leicester Department of Genetics and Genome Biology

General background . How many fingers am I holding up? What day of the week is it? Follow my finger? These three questions are designed to test your sensory, memory and motor neural abilities following an accident; all three systems are affected by a severe deceleration of your brain. Read more

Supervisors: Dr B Warren, Dr E Rosato, Dr R Feuda

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Evaluating the impact of genotoxic aldehyde stress in premature ageing

University of Leicester Department of Chemistry

Aldehydes are highly reactive chemicals that are common pollutants and human metabolites. However, the vast majority of aldehydes’ biological functions are unknown. Read more

Supervisors: Dr R Hopkinson, Dr K Tanaka

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Revealing Reactivity in Cancer-Associated Heme Proteins: Novel Time-Resolved Structural Approaches

University of Leicester Molecular and Cell Biology

Indoleamine 2,3-dioxygenase 1 (IDO1) is a heme-containing enzyme involved in the degradation of tryptophan to kynurenine. Cancer cells upregulate IDO1 to escape normal immune responses and, in many cases, a high expression of IDO1 is connected to poor prognosis. Read more

Supervisors: Dr HK Kwon, Dr P A Ash

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Molecular level understanding of Mycobacterium tuberculosis

University of Leicester Department of Respiratory Sciences

Mycobacterium tuberculosis has evolved to survive and replicate inside macrophages. The project will investigate the molecular mechanisms underpinning adaptation to this specialised intracellular niche. Read more

Supervisors: Dr H O'Hare, Dr N Garton

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Nuclear and transcriptional dysregulations during cellular senescence

University of Leicester Molecular and Cell Biology

Cellular senescence, which is characterised by a proliferation arrest, is a driver of ageing (1). Several stresses can induce cellular senescence, including persistent DNA damage, telomere dysfunction, and oncogene activation. Read more

Supervisors: Dr MT Tellier, Dr Y Markaki

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Investigating the role of SUMOylation in meiotic recombination and chromosome segregation in Arabidopsis

University of Leicester Department of Genetics and Genome Biology

Research Group: Midlands Integrative Biosciences Training Partnership (MIBTP)

Post-translational modifications of proteins such as phosphorylation, methylation and acetylation have been extensively studied in eukaryotes and now the Small Ubiquitin modifier (SUMO) is gaining attention for its importance in fundamental biological roles. Read more

Supervisors: Dr J Higgins, Dr D Guttery

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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We have 10 Molecular Biology PhD Projects, Programmes & Scholarships for UK Students in Leicester

Molecular Biology PhD Projects, Programmes & Scholarships for UK Students in Leicester

We have 10 Molecular Biology PhD Projects, Programmes & Scholarships for UK Students in Leicester

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