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Public Health & Epidemiology PhD Projects, Programs & Scholarships in Leicester

We have 13 Public Health & Epidemiology PhD Projects, Programs & Scholarships in Leicester

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Showing 1 to 10 of 13
  Understanding transcription mediated methylation of intragenic CpG islands in health and disease
  Dr C Tufarelli, Prof S Cowley
Application Deadline: 6 January 2019
1. Project outline describing the scientific rationale of the project (max 4,000 characters incl. spaces and returns). DNA methylation is an epigenetic modification that affects gene expression without altering gene sequences.
  Harnessing large-scale genomic sequencing data to understand smoking behaviour
  Dr C Batini
Applications accepted all year round
In 2018 it has been announced that both whole exome sequences and whole genome sequences will be analysed in the 500K individuals in UK Biobank over the next two to five years.
  Genetic variants associated with multiple diseases
  Prof M Tobin
Applications accepted all year round
As increasing numbers of genetic associations are discovered, it is becoming clear that some genetic variants are associated with more than one or human phenotype (including disease phenotypes).
  Improving overheating risk assessment procedures in urban dwellings
  Dr C Hopfe
Application Deadline: 3 January 2019
Reference number. ABCE18/CH. Start date of studentship. 1 April 2019. Closing date of advert. 3 February 2019. Interview date. tbc.
  Characterising Clostridium difficile defence strategies against bacteriophages
  Prof M Clokie, Dr A Millard
Application Deadline: 6 January 2019
Healthcare associated infections are a major problem for patients and a global health challenge. Clostridium difficile infection (CDI) is particularly problematic, for example the UK has ~20,000 infectious diarrhoeal cases every year, and progressive complications can lead to death in ~3% of infected patients.
  Serine/threonine protein kinase mediated regulation of protein secretion in mycobacteria
  Dr G Mukamolova, Dr H O'Hare
Application Deadline: 6 January 2019
Tuberculosis remains a major global threat as it affects humans and production animals. Mycobacterium tuberculosis and Mycobacterium bovis, the causative agents of tuberculosis in human and animals, are highly successful pathogens which secrete multiple virulence factors.
  Regulation of neuronal excitability and synaptic transmission by metabolic demand in health and disease
  Prof I D Forsythe, Dr J Steinert
Application Deadline: 6 January 2019
The brain uses vast metabolic resources to maintain electrical excitability and to integrate sensory information (Harris et al., 2012).
  Reorganisation of cortical microcircuit activity under anaesthesia
  Dr M O Okun, Dr V Marra
Application Deadline: 6 January 2019
How does general anaesthesia work? Although general anaesthetics are in use for over 150 years, the outlines of the answer began to emerge only in the last decades.
  Using state-of-the-art proteomics to study the cellular and extracellular protein composition in human kidney disease; identification of novel biomarkers and bioactive drug targets in IgA Nephropathy
  Dr A Didangelos, Prof J Barratt
Applications accepted all year round
One of the key pathological characteristics of IgA nephropathy (IgAN) is the maladaptive and chronic accumulation and remodelling of the extracellular matrix (ECM) in affected glomeruli leading to fibrosis and progressive loss of function.
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