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Bioinformatics PhD Projects, Programs & Scholarships in Liverpool

We have 22 Bioinformatics PhD Projects, Programs & Scholarships in Liverpool

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Showing 1 to 15 of 22
  Novel biomarker discovery in heart failure: A metabolomics and systems biology approach
  Prof GYH Lip, Prof D Kell
Application Deadline: 16 March 2020

Funding Type

PhD Type

Health failure is a highly prevalent condition, and a major cause of death and hospitalisation. Heart failure results in major healthcare costs, and much focus has been directed towards earlier diagnosis and detection, so that established treatments can be introduced.
  Molecular analysis of the dynamic sulfotyrosine proteome
  Prof C E Eyers, Prof P Eyers, Dr A R Jones
Applications accepted all year round

Funding Type

PhD Type

The survival of an organism depends upon the ability of different cell types to communicate with each other by assembling the correct complexes of proteins at the correct time in the correct place.
  Multi-omics investigations for enhanced understanding of NF-κB mediated drug resistance
  Prof R Goodacre, Prof N Perkins, Prof C E Eyers, Dr A R Jones
Application Deadline: 1 June 2020

Funding Type

PhD Type

We have an established system that can be used to investigate the role of NF-κB signalling in the cancer cell response to DNA replication stress and have generated cell lines which are resistant to treatment with a highly selective and specific CHK1 inhibitor (CCT244747).
  Validation of owner-reported mobility data using a tool developed for the Generation Pup longitudinal study
  Prof E Comerford, Dr KT Bates
Application Deadline: 31 January 2020

Funding Type

PhD Type

Owner-based questionnaires verified with objective gait data are available for use in dogs already diagnosed with osteoarthritis to help accurately quantify changes in mobility.
  Single-cell proteomic analysis of host-factor cleavage during norovirus infection
  Dr E Emmott, Dr M Iturriza
Applications accepted all year round

Funding Type

PhD Type

Human norovirus is a major human pathogen, and the causative agent behind ‘winter vomiting disease’. Typically, infection is self-limited, causing diarrhoea and vomiting lasting from 24-72 hours.
  Graduate Teaching Assistant (GTA) PhD Studentships - Biological Sciences

Funding Type

PhD Type

A fantastic opportunity to study for a fully funded doctorate whilst gaining valuable teaching experience.
  Moving the tipping point: the decision to anticoagulate patients with atrial fibrillation
  Dr RW Wilkinson, Dr IS Siekmann, Prof G Lip, Prof P Lisboa
Applications accepted all year round

Funding Type

PhD Type

Atrial fibrillation (AF) is a heart condition that causes an irregular and often abnormally fast heart rate, and leads to a high risk of stroke and death.
  Development of metabolomics for understanding AMR in mixed infections
  Prof R Goodacre
Applications accepted all year round

Funding Type

PhD Type

Without correct antibiotic stewardship we could be cast back to a pre-infective era where we have run out of antibiotics to treat life-threatening infections.
  Understanding and dissecting microbial communities with Raman spectroscopy
  Prof R Goodacre
Applications accepted all year round

Funding Type

PhD Type

We have shown that it is possible to label bacteria with heavy isotopes of carbon (13C) and nitrogen (15N) and this incorporation within cellular biomass of heavy isotopes has led to significant shifts in certain vibrational modes from amino acids and nucleic acids that can be readily detected with Raman spectroscopy.
  Novel non-coding RNAs in Drug response, DNA Damage and Aging
  Dr A Kanhere
Applications accepted all year round

Funding Type

PhD Type

Background. One of the biggest surprises of human genomic sequencing was the finding that only ~2% of the genome codes for proteins.
  Analysis of Heparin Binding Proteins and the Supramolecular Structure of Extracellular Matrix
  Prof D G Fernig, Prof C E Eyers
Applications accepted all year round

Funding Type

PhD Type

Changes in heparan sulfate structure and location have long been associated with Alzheimer’s disease, but the functional significance of this has remained elusive.
  The genomics of sperm killing gene drive
  Dr T Price, Prof G Hurst, Prof S Paterson
Applications accepted all year round

Funding Type

PhD Type

Many selfish genetic elements spread rapidly through populations by killing gametes that do not carry them. This fascinating phenomena also has practical applications.
  Evolutionary insights for engineering improved globin oxygen carriers
  Dr M Berenbrink, Dr J Madine
Applications accepted all year round

Funding Type

PhD Type

Around 2 million red blood cell units at a cost of 120.00 GBP per unit are transfused annually in England alone (http://www.nhsbt.nhs.uk/what-we-do/blood-transfusion/).
  Developing and applying computational methods to understand the genetics of ageing
  Dr JP de Magalhaes
Applications accepted all year round

Funding Type

PhD Type

Ageing is the chief biomedical challenge of the 21st century, yet it remains a major puzzle of biology. Although it is clear that the process of ageing has a strong genetic component, much work remains to elucidate how the genome regulates ageing.
  Uncovering the mechanisms of cryoprotectant toxicity and improving cryopreservation protocols
  Dr JP de Magalhaes
Applications accepted all year round

Funding Type

PhD Type

Cryopreservation is the process of placing cells, organs or even whole organisms at low temperatures so that they remain in a state of suspended animation and function is preserved.
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