The main overall aim of this project is to understand mechanisms of joint degeneration during osteoarthritis progression in order to define new targets for therapy. Read more
We depend on healthy joints to stay active, independent and productive. Disorders of the joints of our spine (intervertebral joints) are particularly disruptive, with back pain and disorders impacting millions of people. Read more
Anterior cruciate ligament injuries are common with a median annual incidence of 0.03% per person overall and up to 3.7% in professional athletes (1). Read more
Bones are tightly regulated structures that remodel their structure to adapt to changes in their mechanical environment. With ageing, this mechanical response is often dampened, leading to bone loss and weakness. Read more
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