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Biophysics PhD Projects, Programs & Scholarships in Liverpool

We have 14 Biophysics PhD Projects, Programs & Scholarships in Liverpool

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Showing 1 to 14 of 14
  Improving Photosynthetic Efficiency - Engineering and Evolution of Light-Harvesting Complexes via Synthetic Biology
  Dr D Canniffe
Applications accepted all year round

Funding Type

PhD Type

Photosynthesis is the ultimate source of food and energy for almost all forms of life. Using sunlight as the energy input, photosynthesis removes carbon dioxide from the atmosphere generating the oxygen and carbohydrate that support complex life.
  Elucidating Disease Mechanisms using New Approaches to Capture Transient Protein Complexes in the Mitochondria
  Prof L-Y Lian
Applications accepted all year round

Funding Type

PhD Type

The mitochondria is the powerhouse of the cell. Its malfunction is the cause of many diseases, ranging from cancer to heart and neurological diseases, which become more prevalent with age.
  Bioinspired nanotopographies to control bacterial adhesion and biofilm formation
  Dr R D'Sa
Applications accepted all year round

Funding Type

PhD Type

By 2050, it is predicted that the rise of resistant strains of bacteria and the ever-growing threat of antimicrobial resistance (AMR) will be the cause of 10 million deaths annually, and will burden the global economy by £64 trillion.
  Understanding and dissecting microbial communities with Raman spectroscopy
  Prof R Goodacre
Applications accepted all year round

Funding Type

PhD Type

We have shown that it is possible to label bacteria with heavy isotopes of carbon (13C) and nitrogen (15N) and this incorporation within cellular biomass of heavy isotopes has led to significant shifts in certain vibrational modes from amino acids and nucleic acids that can be readily detected with Raman spectroscopy.
  Novel non-coding RNAs in Drug response, DNA Damage and Aging
  Dr A Kanhere
Applications accepted all year round

Funding Type

PhD Type

Background. One of the biggest surprises of human genomic sequencing was the finding that only ~2% of the genome codes for proteins.
  Evolutionary insights for engineering improved globin oxygen carriers
  Dr M Berenbrink, Dr J Madine
Applications accepted all year round

Funding Type

PhD Type

Around 2 million red blood cell units at a cost of 120.00 GBP per unit are transfused annually in England alone (http://www.nhsbt.nhs.uk/what-we-do/blood-transfusion/).
  TDP-43 The Key protein for finding a cure for Motor Neurone Disease
  Dr S Antonyuk, Prof S Hasnain
Applications accepted all year round

Funding Type

PhD Type

Motor neurone disease is a progressive, fatal neurological disorder with no known cure. It is characterised by selective loss of motor neurons in the spinal cord and cortex.
  SOD1 The Key protein for finding a cure for familial Motor Neurone Disease
  Dr S Antonyuk, Prof S Hasnain
Applications accepted all year round

Funding Type

PhD Type

Motor neurone disease is a progressive, fatal neurological disorder with no known cure. It is characterised by selective loss of motor neurons in the spinal cord and cortex.
  Methionine adenosyltransferases in disease and regulation of gene expression
  Dr S Antonyuk, Prof S Hasnain
Applications accepted all year round

Funding Type

PhD Type

Transmethylation, the transfer of a methyl group from one molecule to another, is a fundamental chemical reaction that plays a central role in important biological processes such as gene expression, cell growth and apoptosis.
  Mass spectrometry analysis of human tissue to characterise cleavage events resulting in amyloid deposition associated with aortic aneurysm and dissection
  Dr J Madine, Prof C E Eyers
Applications accepted all year round

Funding Type

PhD Type

The most common form of localised amyloid occurs in the aorta (aortic medial amyloid; AMA) and is estimated to occur in 97% of Caucasian people over 50.
  Mitochondrial protein folding and diseases
  Prof L-Y Lian, Dr D Criddle
Applications accepted all year round

Funding Type

PhD Type

Many diseases, including cancer and neurological disease, stem from mitochondrial dysfunctions often triggered by sudden elevation of agents such as calcium and reactive oxygen species.
  Characterising and repurposing cyanobacterial CO2-fixing organelles for metabolic engineering
  Prof LN Liu, Dr J Hartwell
Applications accepted all year round

Funding Type

PhD Type

Compartmentalisation represents an effective strategy used by cells to enhance their activities. By creating physical barriers and compartments, cells sequester the metabolic pathways from the cellular milieu to allow controls of metabolic flux and toxic diffusion.
  Exploiting advanced methods for protein structure prediction
  Dr D J Rigden, Dr R Keegan
Applications accepted all year round

Funding Type

PhD Type

Protein structural information is crucial for an understanding of protein function and evolution. Currently, there is only experimental data for a tiny fraction of the protein universe.
  Investigating the molecular mechanisms and consequences of ANP aggregation for cardiovascular disease; a computational and experimental approach
  Dr J Madine, Dr D J Rigden, Dr M Winn
Applications accepted all year round

Funding Type

PhD Type

Atrial natriuretic peptide (ANP) is a cardiovascular hormone synthesised and secreted by myocytes in the atrial wall where it regulates atrial blood volume and vasodilation.
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