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Cell Biology / Development PhD Projects, Programs & Scholarships in Liverpool

We have 20 Cell Biology / Development PhD Projects, Programs & Scholarships in Liverpool

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Showing 1 to 15 of 20
  Understanding molecular processes that control cell adhesion and migration
  Dr I Barsukov, Dr T Zech
Applications accepted all year round

Funding Type

PhD Type

Cells have an amazing ability to form complex tissues, differentiate and migrate. All these processes are controlled by a network of proteins that constantly change their activity and interactions in response to the environment.
  Establishing and validating different histology-based approaches to quantitatively assess efficacy of therapies in an animal model of ischaemia reperfusion injury (IRI)
  Dr L Ressel, Prof P Murray, Dr B Wilm
Application Deadline: 30 June 2020

Funding Type

PhD Type

Acute and chronic kidney disease in children is increasing but new therapies to help treat and prevent the progression of the disease are lacking.
  Molecular analysis of the dynamic sulfotyrosine proteome
  Prof C E Eyers, Prof P Eyers, Dr A R Jones
Applications accepted all year round

Funding Type

PhD Type

The survival of an organism depends upon the ability of different cell types to communicate with each other by assembling the correct complexes of proteins at the correct time in the correct place.
  Mitochondrial protein folding and diseases
  Prof L-Y Lian, Dr D Criddle
Applications accepted all year round

Funding Type

PhD Type

Many diseases, including cancer and neurological disease, stem from mitochondrial dysfunctions often triggered by sudden elevation of agents such as calcium and reactive oxygen species.
  Understanding non-genetic inheritance in Daphnia magna with Raman spectroscopic imaging and mass spectrometry-based metabolomics
  Dr H Muhamad Ali, Dr S J Plaistow, Prof R Goodacre
Applications accepted all year round

Funding Type

PhD Type

Inheritance is an integral part of the evolutionary process. We all know that offspring inherit genes from their parents. But it is now increasingly recognised that parents also transmit ’non-genetic’ factors that interact with genes to shape offspring development.
  Elucidating Disease Mechanisms using New Approaches to Capture Transient Protein Complexes in the Mitochondria
  Prof L-Y Lian
Applications accepted all year round

Funding Type

PhD Type

The mitochondria is the powerhouse of the cell. Its malfunction is the cause of many diseases, ranging from cancer to heart and neurological diseases, which become more prevalent with age.
  Characterization and functional analysis of a novel cancer-associated gene
  Dr JP de Magalhaes
Applications accepted all year round

Funding Type

PhD Type

This opportunity will remain open until the position has been filled. In order to identify new candidate cancer-related genes, our lab developed a bioinformatics “guilt-by-association” method to identify and rank genes that are co-expressed with known cancer-related genes.
  Multicellular Cell Differentiation Model: The control of root hair patterning in Aspergillus thaliana
  Dr N Savage, Dr A Bishopp
Applications accepted all year round

Funding Type

PhD Type

Plants absorb water and nutrients from the soil through hairs that grow along their roots. As such, being able to manipulate root hair numbers may be advantageous to the development of crops more resistant to drought and nutrient deficient soils.
  Investigating the mechanisms driving meiotic gene re-expression in cancer
  Dr U McClurg, Dr W Wei Tee
Applications accepted all year round

Funding Type

PhD Type

Meiosis is a specialised type of cell division which involves genome rearrangements. Many of the genes involved in meiotic homologous recombination are meiosis-specific however, they also constitute a latent toolbox of chromosome remodelling and recombination factors, which can be exploited by cancer cells.
  Using embryonic stem cell models to determine the importance of post transcriptional gene regulation in the early stages of embryo development
  Dr S Tew, Dr D Turner
Applications accepted all year round

Funding Type

PhD Type

This opportunity will close once a successful applicant has been appointed. This project will examine how regulators of gene expression at the post transcriptional level, affect the very earliest processes of embryo development.
  Exploring the role of meiotic proteins in cancer
  Dr U McClurg
Applications accepted all year round

Funding Type

PhD Type

Cancer is one of the main causes of death worldwide. The main challenge is the development of treatments specifically targeting cancers without killing healthy cells.
  Single-cell proteomic analysis of host-factor cleavage during norovirus infection
  Dr E Emmott, Dr M Iturriza
Applications accepted all year round

Funding Type

PhD Type

Human norovirus is a major human pathogen, and the causative agent behind ‘winter vomiting disease’. Typically, infection is self-limited, causing diarrhoea and vomiting lasting from 24-72 hours.
  Defining the role of NF-𝜅B during embryonic stem cell differentiation
  Dr D Turner, Prof A McArdle
Applications accepted all year round

Funding Type

PhD Type

Mouse Embryonic stem cells (mESCs) are a useful system to probe early development. They can be maintained in a pluripotent state in culture, and differentiated using well-defined protocols to all tissue types of the embryo proper.
  Mechanistic mathematical/computational modelling of the PAR polarity network
  Dr N Savage, Dr J Rodriguez
Applications accepted all year round

Funding Type

PhD Type

Cell function is dependent on cell shape. For example, dendritic spine morphology changes from filopodia, which are thought to be searching structures, to mushroom shaped once a potential synaptic connection is found, increasing the postsynaptic surface.
  The Biology of Parasitism in Parasitic Nematodes
  Prof M Viney
Applications accepted all year round

Funding Type

PhD Type

We work on the biology of parasitic nematode worms, particularly Strongyloides spp. The recent, detailed characterisation of the Strongyloides genome (Hunt et al.
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