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Cell Biology / Development PhD Projects, Programs & Scholarships in Liverpool

We have 33 Cell Biology / Development PhD Projects, Programs & Scholarships in Liverpool

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Showing 21 to 30 of 33
  LaNts in wound repair, stem cell activation and squamous cell carcinoma
  Dr K Hamill
Applications accepted all year round

Funding Type

PhD Type

The Laminin N terminus proteins (LaNts) are a relatively unstudied protein family that are related to netrins and laminins. To date there are only two publications and one preprint about the LaNt proteins in the literature which means there is a massive potential to do novel, ground breaking research in this area.
  LaNts and laminins in breast cancer
  Dr K Hamill
Applications accepted all year round

Funding Type

PhD Type

The laminins are a family of proteins that make up part of specialised regions of extracellular matrix termed basement membranes.
  Taking control of cancer-associated splicing switches
  Dr K Hamill
Applications accepted all year round

Funding Type

PhD Type

In cancer, numerous changes to protein expression occur. Some of these are the result of changes to gene transcription or mRNA degradation rates, however, it has increasingly apparent that changes to alternative splicing profile are a key driver of cancer progression.
  Multicellular Cell Differentiation Model: The control of root hair patterning in Aspergillus thaliana
  Dr N Savage, Dr A Bishopp
Applications accepted all year round

Funding Type

PhD Type

Plants absorb water and nutrients from the soil through hairs that grow along their roots. As such, being able to manipulate root hair numbers may be advantageous to the development of crops more resistant to drought and nutrient deficient soils.
  The molecular mechanisms underlying reproductive organ photosynthesis
  Dr D O'Maoileidigh
Applications accepted all year round

Funding Type

PhD Type

Increasing crop yields while decreasing environmental impacts of agriculture is one of the major challenges facing modern society.
  Mechanistic mathematical / computational modelling of integrin signalling
  Dr N Savage, Dr M Morgan
Applications accepted all year round

Funding Type

PhD Type

Regulation of adhesion dynamics and mechanosensation controls cell migration, microenvironment remodelling and global cell fate decisions.
  Development of treatment for Osteoarthritis by blocking metalloproteinases
  Prof G Bou-Gharios
Applications accepted all year round

Funding Type

PhD Type

MMP13 (collagenase 3) plays a vital role in the pathogenesis of osteoarthritis (OA) because MMP13 preferentially cleaves type II collagen, the main component of cartilage, and both MMP13 levels and enzymatic activity are enhanced in OA.
  Understanding basic biological mechanisms and the development of targeted therapies
  Prof G Bou-Gharios
Applications accepted all year round

Funding Type

PhD Type

The PhD proposal is aimed at understanding some of the fundamental mechanism(s) that control extracellular matrix (ECM) proteins and to develop new technologies and therapeutic based on changes in fibroblast gene expression profiling and surface antibodies during the development of connective tissue fibrosis.
  Understanding bone mass using collageneases and aggrecanases
  Prof G Bou-Gharios
Applications accepted all year round

Funding Type

PhD Type

Bone is not only essential for locomotion, support and protection but crucial for many aspects of animal and human health. Specifically, bone is a calcium/phosphorous reservoir, is integral to glucose metabolism, houses the hematopoietic system and cross-talks with renal and reproductive systems.
  microRNAs as tools to regulate senescence of musculoskeletal cells during ageing
  Dr K Whysall, Prof P Clegg
Application Deadline: 22 November 2019

Funding Type

PhD Type

As the ageing population continues to increase, it is important to address ageing-related health issues. There is currently no effective treatments for many common musculoskeletal (MSK) disorders, such as sarcopenia or osteoarthritis, which increase in prevalence during ageing.
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