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We have 9 Pathology PhD Projects, Programmes & Scholarships in Liverpool

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Medicine

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Liverpool  United Kingdom

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Pathology PhD Projects, Programmes & Scholarships in Liverpool

We have 9 Pathology PhD Projects, Programmes & Scholarships in Liverpool

Establishing the biomarker potential of extracellular RNA structure in chronic diseases

Extracellular RNAs have emerged as potentially important components of intracellular communication mechanisms. Often encapsulated within vesicular structures, the roles that they perform in are still not fully established. Read more

Investigating local invasion in primary and secondary brain tumours

Brain tumours are highly invasive and carry a poor prognosis. Secondary brain tumours or brain metastases (BM) are the most common tumours found in the brain affecting up to one third of patients with solid organ cancer. Read more

Preclinical testing of collagen synthesis inhibitors for fibrotic disease

Fibrotic disease is characterised by an excessive accumulation of collagen within tissues, which then impedes tissue function. Organ fibrosis specifically kidney fibrosis, liver fibrosis, cardiac fibrosis and lung fibrosis have limited treatment options, pose a huge clinical burden and are life-limiting diseases. Read more

Elucidation of a new pathological mechanism for brittle bone disease

The incidence of the brittle bone disease osteogenesis imperfecta (OI) is estimated to be around 1 in 10,000 individuals. The phenotypic spectrum of OI ranges from mild to perinatal lethal and includes extra-skeletal connective tissue manifestations. Read more

Alterations in reparative dentinogenesis with ageing, gender and genetic predisposition

Dental pulp exposure caused by tooth decay or injury can lead to life-threatening infections. Following injury, reparative dentinogenesis serves a vital purpose through the accelerated generation of tertiary dentine, comprising mineral and type I collagen. Read more

Control of bone shape and function by the extracellular matrix Fibrillin-1

Bones are tightly regulated structures that remodel their structure to adapt to changes in their mechanical environment. With ageing, this mechanical response is often dampened, leading to bone loss and weakness. Read more
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