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Cell Biology / Development PhD Projects, Programs & Scholarships in London

We have 65 Cell Biology / Development PhD Projects, Programs & Scholarships in London

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Showing 1 to 30 of 65
  Human chromosome segregation principles: Regulation of Astrin-PP1 interaction
  Prof VM Draviam, Prof RW Pickersgill, Dr JM Martin
Application Deadline: 26 April 2020

Funding Type

PhD Type

The School of Biological and Chemical Sciences at Queen Mary is one of the UK’s elite research centres, according to the 2014 Research Excellence Framework (REF).
  Role of cilia in oncogenic signaling and drug resistance
  Dr B Tanos
Applications accepted all year round

Funding Type

PhD Type

Primary cilia are microtubule-based antennae that detect mechanical and chemical stimuli. Although cilia house a number of oncogenic molecules (including Smoothened, KRAS, EGFR, and PDGFR), their precise role in cancer remains unclear.
  Mechanisms of cilia biogenesis and signalling
  Dr B Tanos
Applications accepted all year round

Funding Type

PhD Type

Cilia are sensory organelles that detect mechanical and chemical stimuli from the environment. They arise from centrioles and function as “antennae” that receive and integrate extracellular signals.
  Disrupting biofilm formation in nosocomial pathogens
  Dr R McCarthy
Applications accepted all year round

Funding Type

PhD Type

A biofilm by definition is a structured community of bacterial cells enclosed in a self-produced polysaccharide matrix and adherent to an inert or living surface.
  Understanding the role of cancer stem cell quiescence in glioblastoma radio-resistance
  Prof S Parrinello
Application Deadline: 14 April 2020

Funding Type

PhD Type

This is project one of three. Cancer Research UK (CRUK) have awarded funding to the Cancer Research UK City of London (CoL) Centre to create a CRUK Radiation Research Unit - RadNet (https://www.colcc.ac.uk/radnet/).
  Regulation of mitotic and meiotic chromosome function by different cohesin complexes
  Research Group: Meiosis
  Dr E Martinez-Perez
Application Deadline: 26 April 2020

Funding Type

PhD Type

Cohesin, the complex that provides sister chromatid cohesion (SCC) to ensure correct chromosome segregation during cell division, belongs to a family of SMC (structural maintenance of chromosomes) proteins conserved from bacteria to humans (1).
  Directing protein modification in living systems with bifunctional molecules
  Prof E Tate
Applications accepted all year round

Funding Type

PhD Type

We welcome applications for a 4-year MRes/PhD studentship funded by EPSRC and Merck Sharp & Dohme (MSD), co-supervised by Professor Edward Tate (Imperial College London and the Francis Crick Institute) and Dr Mark Rackham (MSD).
  Next-generation biosensors for real-time, enhanced sensitivity antigen detection
  Dr A Ivanov
Applications accepted all year round

Funding Type

PhD Type

The ability to measure biomarkers and trace analytes both specifically and selectively at the single- molecule level in biological fluids has the potential to transform the diagnosis, real-time screening, analyte seining for specific hazardous materials of high-profile defence interest.
  Novel microfluidic organ on a chip technologies and artificial cells for therapeutics delivery
  Dr N Kamaly
Applications accepted all year round

Funding Type

PhD Type

Technological advances in the fields of microfluidics and tissue engineering have enabled the establishment of biomimetic lab-on-a-chip systems that resemble human biology at the cellular, tissue and organ levels.
  Unravelling epigenetic drivers of chemo-resistance by optical editing of DNA-methylation in cells
  Dr M Di Antonio
Applications accepted all year round

Funding Type

PhD Type

Aberrant DNA-methylation is a well-established driver of acquired resistance in ovarian cancer, although such epigenomic changes occur within a high background of passenger events and current epigenetic chemical biology tools generally affect the entire epigenome rather than locus specific.
  Elucidating the glioblastoma epigenome
  Prof S Marino, Prof D Sheer
Application Deadline: 12 April 2020

Funding Type

PhD Type

A graduate with interest in Brain Tumourigenesis and with experience in Molecular Biology or Cell Biology with at least an upper second class honours degree is required for this project based in the Brain Tumour Research Centre of Excellence led by Prof Silvia Marino at the Blizard Institute.
  Development of a deep learning-based approach to characterise the immune landscape in liver cancer
  Dr Y Yuan, Dr N Guerra
Application Deadline: 17 April 2020

Funding Type

PhD Type

For details on how to apply please visit. http://icr.ac.uk/imperial-icr (please note we only take applications via our online recruitment system).
  Tissue engineering a patch to repair neural tube damage during in utero surgery for spina bifida
  Dr G Galea, Prof P De Coppi, Prof N Elvassore
Application Deadline: 1 May 2020

Funding Type

PhD Type

A 3-year PhD Studentship funded by National Institute for Health Research Great Ormond Street Hospital Biomedical Research Centre (NIHR GOSH BRC) is available within the Developmental Biology and Cancer programme at UCL GOS Institute of Child Health and within the ‘Advanced Treatments for Structural Malformation and Tissue Damage’ research theme within the GOSH BRC.
  Tissue engineering a retinal patch using stem cell-derived photoreceptors to treat retinal dystrophy
  Prof J Sowden, Prof N Elvassore
Application Deadline: 1 May 2020

Funding Type

PhD Type

A 3-year PhD Studentship funded by National Institute for Health Research Great Ormond Street Hospital Biomedical Research Centre (NIHR GOSH BRC) is available within the Developmental Biology and Cancer programme at UCL GOS Institute of Child Health and within the ‘Advanced Treatments for Structural Malformation and Tissue Damage’ research theme within the GOSH BRC.
  Accelerating our ability to understand and target complexity and heterogeneity in cancer through automated imaging of 3D cancer models including patient derived organoids
  Dr C Dunsby, Prof P French
Application Deadline: 31 August 2020

Funding Type

PhD Type

Drug resistance is a major challenge for cancer therapy, arising from heterogeneous cellular behaviours within tumours, where initially identical clonal cells can mutate and adapt to diverse microenvironments.
  Development of oblique plane microscopy to accelerate our ability to understand and target complexity and heterogeneity in cancer
  Dr C Dunsby, Dr C Bakal
Application Deadline: 31 August 2020

Funding Type

PhD Type

Increasingly, the use of conventional 2-D cell cultures (typically monolayers of cells on glass or plastic substrates) are being found to be inadequate as models of biological systems for the purposes of fundamental biology research and drug discovery.
  Translational studies of the immune environment in newly diagnosed bladder cancer and changes induced by treatment
  Prof N James, Prof A Melcher
Application Deadline: 3 April 2020

Funding Type

PhD Type

For details on how to apply using our online recruitment system please see http://icr.ac.uk/phds. There has been a growing interest in manipulation of the immune response in cancer with an increasing number of drugs being licenced, mostly in the metastatic disease setting.
  Tumour evolution in super-resolution: Developing new Artificial Intelligence based methods to analyse 4D imaging data of tumour communities
  Prof C Bakal, Dr C Dunsby
Application Deadline: 3 April 2020

Funding Type

PhD Type

For details on how to apply using our online recruitment portal please see http://icr.ac.uk/phds. Developing new cancer therapies requires improved understanding of heterogeneity in cell behaviour.
  In silico discovery of the degrons and the degron-mediated recruitment modules of the human Ubiquitin E3 Ligase system
  Dr N Davey
Application Deadline: 3 April 2020

Funding Type

PhD Type

For details on how to apply using our online recruitment system please see http://icr.ac.uk/phds.
  Gene regulatory networks in the early zebrafish embryo
  Dr F Wardle
Applications accepted all year round

Funding Type

PhD Type

A PhD studentship is available to work in the laboratory of Dr. Fiona Wardle (www.kcl.ac.uk/research/profile/wardle-group) in the Randall Centre for Cell and Molecular Biophysics, King’s College London.
  Manufacturing bio functional PEEK implants by 3D printing and surface functionalisation with bioactive peptides
  Dr L Veschini, Dr T Coward
Applications accepted all year round

Funding Type

PhD Type

Surgery to remove cancer in the head and neck regions can result in severe tissue defects that cannot regenerate spontaneously.
  Investigating Therapeutic Effect of Different Antioxidants in Friedreich’s Ataxia (FRDA)
  Dr S Anjomani-Virmouni
Applications accepted all year round

Funding Type

PhD Type

Friedreich’s ataxia (FRDA) is an inherited neurodegenerative disorder caused by epigenetic silencing of the frataxin gene. It is the most common inherited ataxia, affecting 1:50,000 Caucasians, and is characterised by neurodegeneration, cardiomyopathy, diabetes mellitus and skeletal deformities.
  Developing new antibody-based therapeutics for neuroblastoma
  Prof A Sala
Applications accepted all year round

Funding Type

PhD Type

Metastatic neuroblastoma is a cancer of the nervous system that kills the majority of the affected children. Although there have been tremendous advances in the understanding of the molecular causes of the disease, patients are still treated with highly toxic mixtures of chemicals and radiation.
  Mathematical modelling of the human hair cycle
  Dr C Higgins
Application Deadline: 20 April 2020

Funding Type

PhD Type

The Higgins and Tanaka labs in the Department of Bioengineering at Imperial College London invite applications for a PhD studentship on systems biology of hair follicle growth and cycling.
  Investigate a novel, unexplored link between WNT signalling and regulators of cell migration in cancer progression using CRISPR-Cas9 and advanced live cell imaging.
  Dr M Krause
Applications accepted all year round

Funding Type

PhD Type

Cancer is a devastating disease. more than one in three people in the UK will develop cancer in their lifetime. WNT signalling is a key pathway controlling morphogenesis in embryos and it has been shown that perturbations of this pathway promote cancer progression.
  Integrated analysis of the Intra-tumour Heterogeneity of Oral squamous cell carcinoma
  Dr I Sequeira
Applications accepted all year round

Funding Type

PhD Type

Cancer is a heterogeneous disease with unique genomic and phenotypic features that differ between individual patients and among different regions within the same tumour.
  Genetic and non-genetic factors involved in risk of cardiovascular diseases
  Dr R Pazoki
Applications accepted all year round

Funding Type

PhD Type

Main Aim. To identify genetic and non-genetic causes of cardiovascular diseases. Cardiovascular diseases including hypertension, myocardial infarction, heart failure, and stroke are the leading causes of mortality worldwide and are expected to keep rising.
  Post-transcriptional regulation of transferrin receptor expression in Trypanosoma brucei
  Dr C Tiengwe
Applications accepted all year round

Funding Type

PhD Type

The goal of this project is to understand how. Trypanosoma brucei. controls expression of iron regulatory proteins in response to changes in intracellular iron.
  Ecology and technology of microbial fuel cells
  Prof T Bell, Prof K Hellgardt
Application Deadline: 24 April 2020

Funding Type

PhD Type

Bacteria can be used to generate electricity. Electrons are produced by bacteria as they decompose organic matter (the "fuel") under anaerobic conditions, and the electricity produced can be stored in a battery or used to power instruments.
  Physics of cutting and reshaping of cell membranes
  Dr A Saric
Applications accepted all year round

Funding Type

PhD Type

We are looking for highly motivated students to join our interdisciplinary team for an exciting project at the interface of physics, biology, and chemistry.
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