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We have 110 PhD Projects, Programmes & Scholarships in Loughborough

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PhD Projects, Programmes & Scholarships in Loughborough

We have 110 PhD Projects, Programmes & Scholarships in Loughborough

Loughborough University

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Obtaining insights into how a signalling hub protein Ras activates multiple effectors

University of Leicester Molecular and Cell Biology
The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. They are highly conserved from yeast to humans, highlighting their fundamental biological roles. Read more
 Supervisors: Dr K Tanaka , Dr R Mahen
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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The Role of Reactive Sulfur Species in the Ageing Heart

University of Leicester Molecular and Cell Biology
Second Supervisor. Prof Melanie Madhani, University of Birmingham. Background . Ageing is a natural and complex biological process that involves the gradual deterioration of cells, tissues, and organ systems over time, thus leading to an increased susceptibility to diseases and mortality. Read more
 Supervisor: Dr C Switzer
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Unlocking the Secrets of Genome Regulation through cryo-EM

University of Leicester Molecular and Cell Biology
Are you an ambitious spirit, ready to make breakthrough discoveries at the frontier of epigenetics? Dive deep into the fascinating world of eukaryotic genomes with us! . Read more
 Supervisors: Dr T Schalch, Dr AC Chaplin
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Using measures of eye movements and EEG to understand effects of cognitive ageing on reading

University of Leicester School of Psychology and Vision Sciences
Healthy ageing is associated with reductions in visual and cognitive abilities that are required for many activities of daily life (e.g., reading, navigation, object-finding). Read more
 Supervisors: Prof K Paterson, Dr A Pagán
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Molecular level understanding of Mycobacterium tuberculosis

University of Leicester Department of Respiratory Sciences
Mycobacterium tuberculosis has evolved to survive and replicate inside macrophages. The project will investigate the molecular mechanisms underpinning adaptation to this specialised intracellular niche. Read more
 Supervisors: Dr H O'Hare, Dr N Garton
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Failures to detect language errors during older age: Evidence of cognitive decline?

University of Leicester School of Psychology and Vision Sciences
Healthy ageing is associated with well-recognised cognitive decline across multiple domains from age 50 onwards (e.g., working memory, processing speed). Read more
 Supervisors: Dr V McGowan, Dr S Gunn
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Epigenetics of early human development: From molecular mechanisms to regenerative medicine

University of Leicester Molecular and Cell Biology
Ever wondered how nature maintains balance of gene expression between sex chromosomes? Well, the 46th chromosome of XX females, the second X, has to be switched off. Read more
 Supervisors: Dr Y Markaki, Dr T Schalch
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Epigenetic ageing and calorie restriction in an insect model system

University of Leicester Department of Genetics and Genome Biology
This project will help establish an insect model for epigenetic ageing, by analysing the effects of calorie restriction on chronological and epigenetic aging in an important insect model, Nasonia vitripennis, extending our discovery of an epigenetic clock in Nasonia. . Read more
 Supervisors: Prof E Mallon, Dr K Chen
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Understanding centrosome function in the human airway

University of Leicester Molecular and Cell Biology
Breathing sustains our life and is also important for our quality of life. Inside the lung, billions of hair-like structures called cilia beat a million times a day to promote a process called mucociliary clearance. Read more
 Supervisors: Dr R Mahen, Prof EH Hollox
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Investigating the role of SUMOylation in meiotic recombination and chromosome segregation in Arabidopsis

University of Leicester Department of Genetics and Genome Biology
  Research Group: Midlands Integrative Biosciences Training Partnership (MIBTP)
Post-translational modifications of proteins such as phosphorylation, methylation and acetylation have been extensively studied in eukaryotes and now the Small Ubiquitin modifier (SUMO) is gaining attention for its importance in fundamental biological roles. Read more
 Supervisors: Dr J Higgins, Dr D Guttery
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Unlocking the genetic potential of barley by modulating recombination

University of Leicester Department of Genetics and Genome Biology
Barley is a major worldwide crop used for malting and animal feed. However, breeding new varieties is constrained by the frequency of genetic crossovers (1-3 crossovers per chromosome pair) and their distribution (biased towards the chromosome ends) that underpin crop improvement1,2. Read more
 Supervisors: Dr J Higgins, Dr D Guttery
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Enhancing meiotic recombination in wheat by modulating RECQ helicases

University of Leicester Department of Genetics and Genome Biology
Wheat accounts for 20% of the calories and protein consumed by humans and is the largest crop in the UK, but yields have plateaued and are susceptible to decline due to extreme weather conditions. Read more
 Supervisors: Dr J Higgins, Dr D Guttery
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Exploring the role of tryptophan metabolism in schizophrenia pathogenesis

University of Leicester Department of Genetics and Genome Biology
L-kynurenine (KYN) and kynurenic acid (KYNA) are metabolites of the kynurenine pathway (KP) of tryptophan degradation and have been found to be increased in the brains of patients with schizophrenia. Read more
 Supervisor: Prof F Giorgini
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Understanding the roles of triacylglycerol in modulating mycobacterial growth and biophysical properties

University of Leicester Department of Respiratory Sciences
Mycobacteria contain more lipid than any other bacteria. In addition to a characteristically lipid-rich cell envelope, mycobacteria can accumulate triacylglycerol (TAG) as cytoplasmic lipid bodies (LBs). Read more
 Supervisors: Dr N Garton , Dr G Mukamolova
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

University of Leicester Molecular and Cell Biology
What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more
 Supervisors: Dr JF Fox, Dr JH Hodgkinson
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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The Evolution of Vision in Mosquitoes

University of Leicester Department of Genetics and Genome Biology
Background . Due to their capacity to transmit viruses such as Zika and parasites like Plasmodium (the causative agent of malaria), mosquitos are regarded by the World Health Organization as one of the most lethal organisms on our planet (WHO | Global vector control response 2017–2030, 2020). Read more
 Supervisors: Dr R Feuda, Dr E Rosato, Dr B Warren
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Molecular Glues as Novel Tools for Tackling Big Challenges in Human Health

University of Leicester Department of Chemistry
Background. The need for new medicines is greater than ever because of an ageing population and the complex clinical challenges brought about by drug resistance and/or side effects. Read more
 Supervisors: Dr RD Doveston, Prof S Macip
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Molecular characterization of Sam68-driven cytoskeletal reorganization

University of Leicester Molecular and Cell Biology
The cytoskeleton is a complex network of various fibres (microtubules, actin, …) that is essential for cells to maintain their shape and internal organization and for their migration. Read more
 Supervisors: Dr C Dominguez, Prof A Fry
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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An assessment of the effects of healthy ageing and transcranial Direct Current Stimulation (tDCS) on human foraging cognition

University of Leicester School of Psychology and Vision Sciences
Identifying cognitive markers of human heathy ageing is of extreme importance considering that global population over age 65 is expected to increase by 120% by 2050. Read more
 Supervisors: Dr C De Lillo, Prof E B. Mukaetova-Ladinska
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Identifying the neurogenetic network underlying visually-driven sleep

University of Leicester Department of Genetics and Genome Biology
General background. Sleep is a behavioural quiescence widely observed in the animal kingdom. During sleep, an animal’s motor activity, as well as their responsiveness to environmental stimuli, are largely reduced. Read more
 Supervisors: Dr K Chen, Dr R Feuda
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Impact of Hypermutability and Restriction-Modification by Campylobacter jejuni, a foodborne pathogen, on Bacteriophage Control Measures

University of Leicester Department of Genetics and Genome Biology
Campylobacter jejuni is a major foodborne pathogen responsible for thousands of cases gastroenteritis every year. The major source of infections by this bacterial pathogen is contaminated poultry products. Read more
 Supervisors: Prof C D Bayliss, Prof M Clokie
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Early life environment changes how organisms age.

University of Leicester Department of Genetics and Genome Biology
This project will help understand why organisms age differently by establishing the effect of early life environments on epigenetic ageing in the model insect, Nasonia vitripennis. Read more
 Supervisor: Prof E Mallon
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Genomics of malignant pleural mesothelioma

University of Leicester Department of Genetics and Genome Biology
Malignant pleural mesothelioma is a rare, incurable cancer that carries a dismal prognosis. Its incidence is increasing globally despite its primary cause, asbestos exposure, having been known for over 50 years. Read more
 Supervisor: Prof E Hollox
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Symbols of power, prestige goods or vibrant materials? Rethinking gold, jet and amber grave goods in Early Bronze Age Britain.

University of Leicester Archaeology and Ancient History
The project forms one strand of the Leverhulme Funded Research Leadership Award, A New History of Bronze. This project explores how the emergence and use of copper and bronze metalworking in this period created new possibilities for crafting, leadership and violence. Read more
 Supervisor: Dr R Crellin
 21 June 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Ground stone in a metallic world

University of Leicester Archaeology and Ancient History
The project forms one strand of the Leverhulme Funded Research Leadership Award, A New History of Bronze. This project explores how the emergence and use of copper and bronze metalworking in this period created new possibilities for crafting, leadership and violence. Read more
 Supervisor: Dr R Crellin
 21 June 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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School of Business Graduate Teaching Assistantship (GTA) funded PhD

University of Leicester
The School of Business is offering fully-funded Graduate Teaching Assistant PhD Studentships starting 23 September 2024. The Graduate Teaching Assistantships are available for full-time campus based registration to our PhD Economics or PhD Management. Read more
 Funded PhD Programme (Students Worldwide)  Business Research Programme
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Investigating the association between cardiometabolic health and labour market outcomes using administrative health data sources

University of Leicester Department of Population Health Sciences
The COVID-19 pandemic had an unprecedented impact on health and work [1]. Read more
 Supervisor: Dr C Razieh
 31 May 2024  PhD Research Project  Funded PhD Project (European/UK Students Only)
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Sarcopenia as a biomarker for people with multiple long-term conditions: an epidemiological perspective

University of Leicester Department of Population Health Sciences
Background . The term ‘multiple long-term conditions’ (MLTCs) refers to the co-existence of two or more chronic conditions (physical or mental) in a person [Navickas et al. Read more
 Supervisor: Dr T Wilkinson
 9 June 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Exploiting raptor genome sequences to combat wildlife crime

University of Leicester Department of Genetics and Genome Biology
Birds of prey have suffered persecution for centuries through trapping, shooting, poisoning and theft from the wild to meet the demand from egg collectors and falconers; they were also amongst the earliest beneficiaries of DNA testing in wildlife forensics. Read more
 Supervisor: Dr C May
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Molecular dissection of horizontal gene transfer mechanisms in mycobacteria

University of Leicester Molecular and Cell Biology
A fully funded PhD position is available within the lab of Dr Abhinav KV at Leicester Institute of Structural and Chemical Biology (LISCB), University of Leicester, UK to carry out structural studies on large macromolecular machines that undertake horizontal gene transfer (HGT) in mycobacteria. Read more
 Supervisors: Dr A Koyamangalath Vadakkepat , Prof J Schwabe
 29 April 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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