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We have 15 Cancer Biology PhD Projects, Programmes & Scholarships in Loughborough
Cancer Biology PhD Projects, Programmes & Scholarships in Loughborough
We have 15 Cancer Biology PhD Projects, Programmes & Scholarships in Loughborough
Harnessing mechanistic technologies and real-world clinical data to advance the interdisciplinary field of obesity and cancer prevention
In England and many other higher income countries, cancer has overtaken cardiovascular disease as the leading cause of mortality. Read more
Cancer biology: identification of new treatment options for EML4-ALK driven lung cancer through understanding mechanisms of cell division and migration.
Lung cancer is the largest cause of cancer-related deaths in the UK and worldwide. While little progress has been made in long-term survival rates, we now have a good understanding of the genetic drivers raising the prospect of earlier diagnosis and more effective treatments. Read more
Understanding the link between fibrosis, inflammation, and breast cancer initiation
Understanding the fundamental molecular events that result in tumour initiation is critical to the prevention and treatment of human cancers. Read more
Transcriptional kinases in cancer and developmental disorders
Cyclin-dependent kinases (CDKs) are protein kinases performing essential functions in regulation of cell cycle and transcription. Read more
Understanding gene regulation by HDAC1 complexes in development and cancer
Packaging DNA into nucleosomes helps protect the long fragile genomes of eukaryotic species. However, in doing so it becomes an ever-present physical barrier to the machinery required for its replication, repair and transcription. Read more
Structural and functional characterisation of MALT1 ubiquitination to aid in the development of novel anti-cancer therapies
Nuclear factor-kappa B (NF-kB) is a family of transcription factors that play a crucial role in regulating various cellular processes; primarily related to immune responses, inflammation, and cell survival. Read more
Structural and functional analysis of the protein complexes which regulate cell fate decisions to identify novel cancer therapies
Whether a cell dies or not has profound consequences on health and disease. In healthy tissue, cells that acquire high levels of genetic damage are safely removed via a process of programmed cell death. Read more
Targeting senescence to ameliorate ageing and treat cancer and other age-related diseases
Ageing is a biological process that affects all humans. Despite the scientific advances of the past decades, the mechanisms that lead to ageing are not fully understood. Read more
Cell Mechanics and Tumour Growth (Ref: UF-YL-2024)
Although plenty of cancer research is in the field of cancer cell biology, there is lack of knowledge that can cascade the biological theory to those measurable parameters that can be obtained non-destructive and in real-time at clinical level, i.e. Read more
Circadian rhythm effects on radiotherapy for prostate and other cancers
Research Group:
Human & Medical Genetics
Radiotherapy is used to treat more than 50% of cancer patients, but up to a quarter of patients suffer side effects that can affect their quality of life in the long-term. Read more
Structural investigation of oncogenic splicing factors
More than 90% of human genes can and do express multiple proteins. This is achieved by a process called alternative RNA splicing, which is an essential step in gene expression in mammals. Read more
Understanding centrosome assembly in healthy and cancerous tissue with imaging
This is an opportunity for a scientist to join the lab of Dr Robert Mahen in the Department of Molecular & Cell Biology at the University of Leicester. Read more
Genomics of malignant pleural mesothelioma
Malignant pleural mesothelioma is a rare, incurable cancer that carries a dismal prognosis. Its incidence is increasing globally despite its primary cause, asbestos exposure, having been known for over 50 years. Read more
Join Our Quest to Unravel the Secrets of Eukaryotic Genomes!
We're on the lookout for passionate PhD students who are eager to delve deep into the mysteries of our DNA. Our quest? To understand the subtle changes that determine how our genes function, both in sickness and in health. Read more
Obtaining an integrated understanding of oncogenic RAS signalling
The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. The physiological importance of RAS signalling is evident as about 25% of all human cancers harbour mutations in ras genes, where kras is most frequently mutated (about 18%) (COSMIC, v94). Read more
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