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Molecular Biology PhD Projects, Programs & Scholarships in Loughborough

We have 31 Molecular Biology PhD Projects, Programs & Scholarships in Loughborough

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Showing 1 to 15 of 31
  PhD Studentship: Influence of phytochemical administration on inflammation, redox balance and muscle regeneration following exercise in older and younger adults
  Dr T Clifford
Application Deadline: 26 June 2020

Funding Type

PhD Type

Reference number. SSEHS/TC. Start date of studentship. 1 October 2020. Closing date of advert. 26 June 2020. Interview date. July/August.
  Bioinspired filomicelles for the effective delivery of antibiotics
  Dr K Suntharalingam, Dr R Britton
Application Deadline: 7 June 2020

Funding Type

PhD Type

Background. Antibiotics are drugs that are used to prevent and treat bacterial infections. Antibiotic resistance occurs when bacteria modify their response to antibiotics, making them less effective or even redundant.
  Structure and function of protein complexes of the eukaryotic glycoprotein folding quality control (ERQC) checkpoint enzyme, UGGT
  Dr P Roversi, Dr C Savva
Application Deadline: 7 June 2020

Funding Type

PhD Type

A wonderfully efficient quality control enzyme in the eukaryotic cell detects and stops glycoproteins that are on the way to be secreted but need time to form properly.
  Understanding microtubule-actin crosstalk in neuronal cell migration
  Prof A M Fry, Prof I D Forsythe
Application Deadline: 7 June 2020

Funding Type

PhD Type

Summary. This BBSRC-funded 4-year PhD studentship will address the mechanism of action of a microtubule-associated protein, EML4, in promoting microtubule-actin crosstalk and neuronal cell migration [1].
  Obtaining mechanistic insights into interplay of multiple effectors of oncogenic RAS molecules
  Dr K Tanaka, Dr A Revyakin
Application Deadline: 7 June 2020

Funding Type

PhD Type

The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. Importantly, about 20% of all human cancers harbour mutations in RAS genes (COSMIC).
  Cryo-Electron Microscopy of Histone Deacetylase Complexes
  Prof J Schwabe, Dr S Cowley
Application Deadline: 7 June 2020

Funding Type

PhD Type

Histone deacetylase complexes play a role in many cellular processes, such as cancer, cell cycle progression and DNA repair. Investigating how these HDAC complexes act to control gene expression and their interactions with other proteins should lead to an understanding of their influence in the cell.
  Molecular Modelling of P2X receptor agonism and antagonism
  Dr R Schmid
Application Deadline: 7 June 2020

Funding Type

PhD Type

P2X receptors (P2XRs) form a family of ligand-gated ion channels activated upon binding of extracellular ATP (for review see [1]).
  Revealing molecular mechanisms of gene silencing
  Dr T Schalch, Dr S Cowley
Application Deadline: 7 June 2020

Funding Type

PhD Type

Regulation of transcription through chromatin architecture is governed by nucleosome remodelers and chromatin modifying complexes.
  Single-molecule analysis of structure and function of human transcription complexes using DNA origami nano-robots
  Research Group: Structural Biology and Molecular Enzymology
  Dr A Revyakin, Prof D Panne
Application Deadline: 6 June 2020

Funding Type

PhD Type

DNA origami is a rapidly evolving area of nanotechnology in which self-assembly properties of the DNA double helix are harnessed to build three-dimensional structures on the dimensional scale of ~50 nm.
  Structural mechanism of signal-dependent gene transcription
  Prof D Panne, Dr A Revyakin
Application Deadline: 7 June 2020

Funding Type

PhD Type

PhD Start date. September 2020. The control of gene transcription is the main regulatory step for cellular gene regulation.
  Structural, kinetic and functional characterisation of ion channel function in the gal-3-fibrosome
  Prof B Gooptu, Prof G Vuister
Application Deadline: 7 June 2020

Funding Type

PhD Type

4 Year PhD Studentship available to start September 2020. Fibrosis is a common ageing-associated process that affects all organs.
  Detection in cells of protein interactions on pre-mRNA during the regulation of splicing
  Prof I C Eperon, Dr S Cowley
Application Deadline: 7 June 2020

Funding Type

PhD Type

One of the biggest challenges in molecular biology is presented by the selection of sites for RNA splicing. We cannot overstate its importance or apparent complexity.
  Use of single molecule fluorescence and cryo-EM to study the regulation of RNA splicing
  Prof I C Eperon, Dr A Hudson
Application Deadline: 7 June 2020

Funding Type

PhD Type

One of the biggest challenges in molecular biology is presented by the selection of sites for RNA splicing. We cannot overstate its importance or apparent complexity.
  Evaluating motor and cognitive function through gaze-control technology
  Dr D Souto
Application Deadline: 7 June 2020

Funding Type

PhD Type

Gaze-control technology has proved invaluable in assisting people with neurodegenerative conditions, such as Motor Neuron Disease (MND) or Cerebral Palsy (CP), at times dramatically improving their quality of life by extending their ability to communicate independently.
  Network interactions shape the circadian clock in Drosophila melanogaster
  Dr E Rosato, Prof C P Kyriacou
Application Deadline: 7 June 2020

Funding Type

PhD Type

The circadian clock is an endogenous mechanism that synchronizes almost all behaviour and physiology with the Earth’s 24 hour environmental cycles.
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