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Biochemistry PhD Projects, Programs & Scholarships in Manchester

We have 76 Biochemistry PhD Projects, Programs & Scholarships in Manchester

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  Soil microbiome function controlling radionuclide bioavailability and soil-to-plant transfer
  Dr J Pittman, Dr C Robinson
Applications accepted all year round
Understanding the behaviour and environmental impacts of radionuclides such as radium (Ra) and uranium (U) is of critical importance for the management and risk modelling of sites with elevated concentrations of these radionuclides.
  Biochemical elucidation of the novel ECP bacterial stress response
  Dr N Dixon, Prof R Breitling
Application Deadline: 20 March 2019
This PhD project will focus on the detailed elucidation of the biochemical mechanism of a recently discovered gene regulatory network in bacteria.
  Role of cutaneous circadian clocks in gating skin repair
  Dr Q-J Meng, Dr M Sherratt
Application Deadline: 31 March 2019
Biological clocks play a key role by temporally controlling the function of whole organisms (including humans) and individual tissues and cells to be aligned with the rhythmic environment.
  Defining the role of UBLylation pathways in the DNA damage response
  Dr C.K Schmidt, Prof A Sharrocks
Application Deadline: 28 February 2019
This 4-year BBSRC Case studentship with AstraZeneca will look at posttranslational modifications with ubiquitin-like proteins (UBLs) within and beyond the DNA damage response (DDR).
  Proteomic approach to understand mitochondrial quality control under normal and stress conditions
  Dr H Lu, Prof S Hubbard
Applications accepted all year round
Defects in protein quality control lead to the accumulation of misfolded and damaged proteins, which play an important role in many diseases (e.g.
  (WIS) How food-borne Listeria monocytogenes overcomes the host defence mechanisms at the single cell level?
  Dr P Paszek, Prof I Roberts
Application Deadline: 28 February 2019
Pathogens have developed intricate ways to overcome the host’s immune system. In this proposal we will study the direct interaction of macrophages with the important food-borne bacterial pathogen Listeria monocytogenes that causes significant human morbidity and mortality.
  (WIS) Determining the role of vascularisation in glomerular development
  Prof R Lennon, Dr R Naylor
Application Deadline: 28 February 2019
The kidney has an essential role in filtering waste and toxins from the blood. When kidney function declines the impact on health is severe.
  (WIS) The application of novel Top down Mass Spectrometry to uncover targeted mutagenesis of DNA repair proteins for exposomics
  Dr A Povey, Prof P Barran, Prof G Margison
Application Deadline: 28 February 2019
Next generation sequencing of human tumour DNA consistently shows large numbers of mutations scattered throughout the genome (e.g.
  (WIS) Understanding the molecular basis of cartilage lubrication – an essential aspect of articular joint function: biophysical approaches to investigate supramolecular synergy
  Prof T Day, Dr C Milner
Application Deadline: 28 February 2019
Articular cartilage, which coats the ends of bones in joints such as hips and knees, is a uniquely well-lubricated tissue. No synthetic material can match the almost frictionless movement between the cartilage surfaces as they slide past each other during joint articulation.
  The mechanism of gating and transport of pentameric Magnesium ion channels
  Dr S M Prince, Prof R Ford
Applications accepted all year round
Magnesium ions are a co-factor in many important biological processes particularly because of the requirement for Mg2+ in the hydrolysis of Adenosine tri-phosphate, the ubiquitous cellular energy source.
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