Biochemistry PhD Projects, Programmes & Scholarships in Manchester

(University of Manchester - University of Tokyo Dual Award) Diversifying Antitumor Drugs through the Integration of Synthetic Biology and Chemo-enzymatic Approaches

The University of Manchester Department of Chemistry

Ecteinascidin 743 (ET-743, Trabectedin) is a marine-derived natural organic compound approved for the treatment of soft tissue sarcomas. Read more

Supervisors: Prof E Takano, Prof H Oguri

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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New Methods for modelling cofactor-dependent enzyme structure and function

The University of Manchester Department of Chemistry

Enzymes are Nature’s catalysts and many used cofactors and/or coenzymes to catalyse their reactions. While AI and homology methods now often allow the useful prediction of protein structure from amino acid sequence, this can be more challenging when the protein/enzyme contain cofactors. Read more

Supervisor: Prof S Hay

27 October 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Characterising human sebum using NMR approaches

The University of Manchester Department of Chemistry

We have recently shown that skin secretions in particular sebum, has a critical diagnostic role in other diseases unrelated directly to the skin. Read more

Supervisors: Dr D K Trivedi, Prof M Nilsson, Prof GA Morris

Year round applications PhD Research Project Self-Funded PhD Students Only

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Synthetic and Mechanistic Studies into Enzymatic Degradation of Waste Plastics

The University of Manchester Department of Chemistry

Plastics are a broad range of solid polymeric materials that have found widespread application globally. However, there has been a steady accumulation of discarded plastics and there is now growing awareness that they present a significant hazard to the natural environment and human health. Read more

Supervisor: Dr L Wong

Year round applications PhD Research Project Self-Funded PhD Students Only

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Defining the molecular mechanisms of leukaemia chemotherapies

The University of Manchester Faculty of Biology, Medicine and Health

Chemotherapies are usually the backbone of cancer treatment for either curative or palliative patient care. Multiple therapies can be used for the same disease, with the choice of drug dependent on parameters such as the patient’s age and fitness. Read more

Supervisors: Dr JK Knight, Dr K Batta, Dr D Wiseman

Year round applications PhD Research Project Self-Funded PhD Students Only

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Characterisation of PA protease from Micrococcus luteus as a novel approach to the management of eczema

The University of Manchester Faculty of Biology, Medicine and Health

The chronic inflammatory skin disease, eczema, now affects approximately 15% of the paediatric population of the Western world and is growing in prevalence. Read more

Supervisors: Prof CN O'neill, Prof A McBain

Year round applications PhD Research Project Self-Funded PhD Students Only

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Viral-surface interactions studied by vibrational sum-frequency spectroscopy

The University of Manchester Department of Materials

The recent COVID-19 pandemic, and in particular fomite transmission of the virus, led to a lot of interest in how viral particles attached to surfaces, their survival times on different materials and how they transferred to hosts. Read more

Supervisors: Dr A Thomas, Dr R Lindsay

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding and preventing the denaturation of proteins on surfaces in manufacture, storage and delivery of biotherapeutics

The University of Manchester Department of Materials

Protein and peptide therapeutics are pharmaceutical drug treatments derived from natural sources. They are applied to a range of diseases from diabetes to novel cancer therapies. Read more

Supervisors: Dr A Thomas, Prof A Saiani

Year round applications PhD Research Project Self-Funded PhD Students Only

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Engineering Ice-Binding Proteins

The University of Manchester Department of Chemistry

Ice-binding proteins are produced by extremophiles to help them survive in the worlds coldest places. They have many potential applications, from the storage of cells/tissue to transport infrastructure. Read more

Supervisor: Prof m Gibson

Year round applications PhD Research Project Self-Funded PhD Students Only

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High-throughput biomaterials discovery

The University of Manchester Department of Chemistry

Polymer biomaterials have revolutionised a range of areas from drug delivery, to antimicrobials, to cellular cryopreservation. There are 1000’s of possible monomer combinations, molecular weights and architectures to be explored, and even small differences can dramatically change their properties. Read more

Supervisor: Prof m Gibson

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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New strategies to cryopreserve cell-based therapies

The University of Manchester Department of Chemistry

In the past decade, cell-based therapies have emerged to transform the treatment of disease, particularly cancer. Whilst potent, these therapies are challenging to deliver in practise as must be stored frozen (cryopreserved). Read more

Supervisor: Prof m Gibson

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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Metals and host-pathogen interactions: the role of metal handling systems in the human gastrointestinal pathogen Campylobacter jejuni

The University of Manchester Faculty of Biology, Medicine and Health

Campylobacter jejuni is a globally important food-borne pathogen causing an estimated 400-500 million cases of acute human gastroenteritis each year. Read more

Supervisors: Dr J Cavet, Dr D Linton

Year round applications PhD Research Project Self-Funded PhD Students Only

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Identification of transcriptomic signatures of autism-like neurodevelopmental disorder

The University of Manchester Faculty of Biology, Medicine and Health

The overarching aim of this project is to define transcriptional patterns and identify new genetic elements essential for the correct development of the human brain. Read more

Supervisors: Dr PG Grzechnik, Dr A J Whitmarsh

Year round applications PhD Research Project Self-Funded PhD Students Only

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NMR approaches for understanding mass transfer in microbial biofilms and sessile microbial communities

The University of Manchester Department of Chemistry

Biofilms are structured sessile communities of microorganisms with relevance in many areas of life. They are almost omnipresent in aquatic and terrestrial ecosystems. Read more

Supervisors: Prof M Nilsson, Prof A McBain

Year round applications PhD Research Project Self-Funded PhD Students Only

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Circadian mechanisms in psoriasis: therapeutic opportunities

The University of Manchester Faculty of Biology, Medicine and Health

Hallmark features of psoriasis symptoms vary through time, suggesting an important role for circadian circuits in driving disease expression, and offering the potential of chronotherapy. Read more

Supervisors: Dr H Young, Dr I Iqbal, Prof D Ray

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 47 Biochemistry PhD Projects, Programmes & Scholarships in Manchester

Biochemistry PhD Projects, Programmes & Scholarships in Manchester

We have 47 Biochemistry PhD Projects, Programmes & Scholarships in Manchester

University of Salford

(University of Manchester - University of Tokyo Dual Award) Diversifying Antitumor Drugs through the Integration of Synthetic Biology and Chemo-enzymatic Approaches

New Methods for modelling cofactor-dependent enzyme structure and function

Characterising human sebum using NMR approaches

Synthetic and Mechanistic Studies into Enzymatic Degradation of Waste Plastics

Defining the molecular mechanisms of leukaemia chemotherapies

Characterisation of PA protease from Micrococcus luteus as a novel approach to the management of eczema

Viral-surface interactions studied by vibrational sum-frequency spectroscopy

Understanding and preventing the denaturation of proteins on surfaces in manufacture, storage and delivery of biotherapeutics

Engineering Ice-Binding Proteins

High-throughput biomaterials discovery

New strategies to cryopreserve cell-based therapies

Metals and host-pathogen interactions: the role of metal handling systems in the human gastrointestinal pathogen Campylobacter jejuni

Identification of transcriptomic signatures of autism-like neurodevelopmental disorder

NMR approaches for understanding mass transfer in microbial biofilms and sessile microbial communities

Circadian mechanisms in psoriasis: therapeutic opportunities

We have 47 Biochemistry PhD Projects, Programmes & Scholarships in Manchester

Biochemistry PhD Projects, Programmes & Scholarships in Manchester

We have 47 Biochemistry PhD Projects, Programmes & Scholarships in Manchester

University of Salford

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