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Bioinformatics PhD Projects, Programs & Scholarships in Manchester

We have 27 Bioinformatics PhD Projects, Programs & Scholarships in Manchester

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Showing 1 to 10 of 27
  Acoustic properties of nanofibre composites
University of Manchester School of Mathematics
  Prof W J Parnell
Application Deadline: 16 September 2019
Noise pollution is a serious problem in many aspects of modern society. Although many materials exist that can provide mechanisms for sound absorption, particularly in the higher frequency ranges, compact low-frequency noise attenuation and absorption remains a significant challenge.
Details
Type/Funding
  Statistical Learning and Adaptive Observation in Clinical Prediction: Methodology and Applications
University of Manchester Faculty of Biology, Medicine and Health
  Dr G P Martin, Dr N Peek, Prof I Buchan
Application Deadline: 28 February 2019
Clinical prediction models (CPMs), which predict the occurrence of an event of interest given what is known about an individual, could enable a personalised and preventative approach to healthcare.
Details
Type/Funding
  (WIS) How food-borne Listeria monocytogenes overcomes the host defence mechanisms at the single cell level?
University of Manchester Faculty of Biology, Medicine and Health
  Dr P Paszek, Prof I Roberts
Application Deadline: 28 February 2019
Pathogens have developed intricate ways to overcome the host’s immune system. In this proposal we will study the direct interaction of macrophages with the important food-borne bacterial pathogen Listeria monocytogenes that causes significant human morbidity and mortality.
Details
Type/Funding
  Exploiting druggability host spots in protein phosphatase targets
University of Manchester Faculty of Biology, Medicine and Health
  Dr L Tabernero, Prof D Procter, Dr S Butterworth
Applications accepted all year round
In the past years the use of virtual screening or computer-based screening of compound libraries against selected targets has expanded exponentially the boundaries of drug discovery.
Details
Type/Funding
  Non-invasive imaging of the pathophysiology of early systemic sclerosis; fibrosis and oxygenation
University of Manchester Faculty of Biology, Medicine and Health
  Dr A Murray, Prof G Parker, Prof A Herrick, Dr M Dickinson
Applications accepted all year round
Systemic sclerosis (SSc) is a microvascular autoimmune disease that causes lack of blood flow and scarring and thickening of skin and tissues within internal organs.
Details
Type/Funding
  Identification, screening and scale up of enzymes in the Biocatalyst Discovery Metagenomics platform
University of Manchester School of Chemistry
  Prof N Scrutton, Prof N Turner
Applications accepted all year round
Background – Enzyme engineering strategies, supported by computational and molecular modelling to maximise speed and efficiency, has been shown to be a powerful tool for (semi-) rational design of enzymes.1,2 We will evaluate protein mobility/dynamics, docking/binding of substrates and calculation of free energy barriers for catalysis.
Details
Type/Funding
  Genetic and immunological basis of rare primary immunodeficiency diseases
University of Manchester Faculty of Biology, Medicine and Health
  Dr P Arkwright, Dr T Briggs, Prof T Hussell
Applications accepted all year round
Objective. To understand the genetic and explore the functional immune basis of rare primary immunodeficiency diseases. Background.
Details
Type/Funding
  WRDTP ESRC PhD Studentships 2019/20
Manchester Metropolitan University
 . The White Rose Social Sciences Doctoral Training Partnership (WRDTP), accredited by the Economic and Social Research Council in 2016, is a collaboration across the social sciences at the Universities of Leeds, Sheffield, York, Bradford, Sheffield Hallam, Hull, and Manchester Metropolitan.
Details
Type/Funding
  A mechanistic understanding of circadian clock-dependent regulation of the secretory pathway
University of Manchester Faculty of Biology, Medicine and Health
  Prof K E Kadler, Dr Q-J Meng, Dr J Swift
Applications accepted all year round
The protein secretory pathway comprises a series of membranous compartments and transport vesicles that cells use to synthesise, post-translationally modify, and move proteins for delivery to the plasma membrane or for secretion to the extracellular matrix.
Details
Type/Funding
  Regulation of gene expression in Drosophila ovarian germline stem cells
University of Manchester Faculty of Biology, Medicine and Health
  Prof H Ashe, Prof M Ashe
Applications accepted all year round
Drosophila germline stem cells (GSCs) are a premier model for understanding stem cell regulation. Upon division, one GSC daughter remains a stem cell, whereas the other differentiates into a cystoblast (CB).
Details
Type/Funding
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