Biological Sciences PhD Projects, Programmes & Scholarships for Self-funded Students in Manchester

We have 138 Biological Sciences PhD Projects, Programmes & Scholarships for Self-funded Students in Manchester

Cell signalling and gene expression dynamics in Drosophila

The University of Manchester Faculty of Biology, Medicine and Health

During Drosophila development, cell signalling and gene expression are regulated in space and time to allow the correct cell fate decisions. Read more

Supervisor: Prof H Ashe

Year round applications PhD Research Project Self-Funded PhD Students Only

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Diabetic Foot Ulcer

Manchester Metropolitan University Faculty of Science and Engineering

PROJECT ADVERT. The management of chronic wounds poses a considerable burden on healthcare systems, with approximately 2.2 million patients currently afflicted, resulting in annual costs of £5.3 billion for the NHS to address wound care and its associated comorbidities, including amputations. Read more

Supervisor: Mr CK Kendrick

1 July 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Neurovascular coupling in cerebral hypoperfusion

The University of Manchester Faculty of Biology, Medicine and Health

There are almost a million people living with dementia in the UK. Most of these cases comprise Alzheimer’s Disease (AD), vascular dementia (VaD) or, as is increasingly recognised, a mixed picture phenotype with evidence of the two conditions co-existent in the same patient. Read more

Supervisors: Dr H Pritchard, Dr A Greenstein, Dr I Schiessl, Prof S Allan

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Investigating the effect of plastics recycling on nanoplastic production in packaging applications

The University of Manchester Department of Materials

Nanoplastics, defined as plastic particles measuring less than 1000 nanometres, have emerged as a significant concern due to their ability to infiltrate ecosystems, posing potential risks to the environment. Read more

Supervisor: Dr T McDonald

25 August 2024 PhD Research Project Funded PhD Project (UK Students Only)

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VariantVisualiser: Ensuring precise diagnoses of genetic disorders through the development of intuitive software that facilitates the integration and visualisation of complex informatics with biological and clinical data.

The University of Manchester Department of Computer Science

Rare diseases affect <1-in-2,000 people, but ~8,000 rare genetic diseases impact ~10% of births globally. These arise from variations in patients’ DNA sequences. Read more

Supervisors: Dr S Pettifer, Dr PF Freeman

Year round applications PhD Research Project Self-Funded PhD Students Only

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(BRC) Nailfold capillary imaging in the idiopathic inflammatory myopathies (Non-Clinical)

The University of Manchester Faculty of Biology, Medicine and Health

The idiopathic inflammatory myopathies (IIMs) are rare conditions characterised by distinct clinical subtypes and varied multisystem involvement. Read more

Supervisors: Dr A Murray, Dr H Chinoy, Dr J Lamb

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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(MRC DTP CASE) Prediction of substrate binding geometry and strength in promiscuous enzymes: computational chemistry applicable to the design of pharmaceuticals and agrochemicals

The University of Manchester Faculty of Biology, Medicine and Health

We are often taught about the power of enzymes to select particular substrates from the biological milieu and of their ability to perform highly selective reactions on those substrates. Read more

Supervisors: Dr A Leach, Dr S De Visser, Dr C Trujillo

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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(MRC DTP CASE) A prototype smart disposable device for ophthalmic point-of-care

The University of Manchester Faculty of Biology, Medicine and Health

This project seeks to design and develop a small device which will fit comfortably behind the lower eyelid in order to soak up a small volume of tears such that the biomarkers contained in tears – including some of the thousands or proteins in the human tear film – can be easily removed and analysed. Read more

Supervisors: Prof P Morgan, Prof J Gough

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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(MRC DTP CASE) Determination of the role of viruses in the microbiome of biofilms formed in the ear of patients with otitis media

The University of Manchester Faculty of Biology, Medicine and Health

Otitis media (OM) is a very common infection of the middle ear characterised by redness, swelling and build-up of fluid behind the eardrum. Read more

Supervisors: Prof P Vallely, Prof P Klapper, Prof S Lovell, Mrs JN Nichani

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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(MRC DTP CASE) Multiomic evaluation of differential drug response in metastatic breast cancers

The University of Manchester Faculty of Biology, Medicine and Health

Breast cancers are the most common cancers in women. Estrogen Receptor (ER) plays a major role in breast cancer growth. To stop the cancer from growing further, clinically successful ER-targeting therapies like Fulvestrant, etc were developed. Read more

Supervisors: Dr S Nagarajan, Dr HH Harrison, Prof R Clarke, Dr I Iqbal

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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(MRC DTP CASE) The emerging fungal order Mucorales: species-specific pathogenic strategies and new diagnostics

The University of Manchester Faculty of Biology, Medicine and Health

Mucormycoses are emerging lethal fungal infections, with striking mortality rates of 50-90% depending on the clinical presentation, infection site and underlying host immune status. Read more

Supervisors: Dr M Bertuzzi, Dr N.V.R Van Rhijn

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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(MRC DTP CASE) Investigating the mechanisms contributing to impaired regulatory function of B cells in autoimmunity

The University of Manchester Faculty of Biology, Medicine and Health

The implementation of biological therapies has significantly advanced the management of autoimmune diseases (AIDs). However, the failure to achieve clinical remission in ‘non-responders’ remains a significant and unmet challenge. Read more

Supervisors: Dr MM Mennon, Prof MH Buch

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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(MRC DTP CASE) Understanding Disease Management and Outcomes for Myositis Patients: An International Real-World Study Utilising Multiple Data Sources to Investigate Treatment Patterns, Health-Related Quality of Life, Clinical Outcomes, and Burden of Illness for Patients With Rare Autoimmune Disease

The University of Manchester Faculty of Biology, Medicine and Health

Myositis is a group of rare conditions which present with physical symptoms that can significantly impact a patient’s life. Many patients are permanently disabled due to irreversible muscle damage. Read more

Supervisors: Dr H Chinoy, Dr AO Oldroyd

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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(MRC DTP CASE) Understanding how tumour associated macrophages control the tumour immune landscape in NF2-Schwannomatosis

The University of Manchester Faculty of Biology, Medicine and Health

Type 2 Neurofibromatosis (NF2), now referred to as NF2-Schwannomatosis (or NF2-SWN), is a rare autosomal dominant tumour pre-disposition syndrome characterised by growth of typically benign tumours throughout the nervous system. Read more

Supervisors: Prof D Brough, Dr K Couper

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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(MRC DTP CASE) An Integrative Structural Biology Platform for Drug Discovery

The University of Manchester Faculty of Biology, Medicine and Health

Solute carriers (SLCs) are the second largest class of membrane-embedded proteins with over 400 members organised into 66 families. Read more

Supervisors: Dr A Politis, Dr CP Pliotas

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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We have 138 Biological Sciences PhD Projects, Programmes & Scholarships for Self-funded Students in Manchester

Biological Sciences PhD Projects, Programmes & Scholarships for Self-funded Students in Manchester

We have 138 Biological Sciences PhD Projects, Programmes & Scholarships for Self-funded Students in Manchester

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