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We have 185 Biological Sciences PhD Projects, Programmes & Scholarships in Manchester
Biological Sciences PhD Projects, Programmes & Scholarships in Manchester
We have 185 Biological Sciences PhD Projects, Programmes & Scholarships in Manchester
Development and Characterization of Hydrogel-Based Model(s) for Pancreatic Cancer
Pancreatic Ductal Adenocarcinoma (PDAC), which develops from cells lining pancreas ducts, represents 95% of all pancreatic cancer cases. Read more
Peptide-mediated nanocarrier drug delivery for enhanced brain targeting and treatment of inflammation
This project involves the study of nanoparticles and drug delivery to the brain. The student would be required to make and characterise novel nanoparticles from special lipid molecules of various compositions more suitable for blood-brain barrier (BBB) targeting. Read more
(Bicentenary) Development and validation of human lung organoids enriched with immune component to assess pulmonary effects of air pollution and micro/nanoplastics
Air pollution has already been linked to adverse human health effects (respiratory illness, cardiovascular disease, and carcinogenesis) in epidemiological studies. Read more
Bioinspired Nanomaterials Based Miniaturised Soft Robots for High Precision Regiospecific Drug Delivery to Malignant Tumours
Cancer is one of the top global public health challenges, estimated to have caused 10M deaths (2020) according to WHO. Throughout the years, standardised therapeutic protocols have been developed and evolved for the treatment of various types of cancers. Read more
VariantVisualiser: Ensuring precise diagnoses of genetic disorders through the development of intuitive software that facilitates the integration and visualisation of complex informatics with biological and clinical data
Rare diseases affect. This proposal builds on substantial efforts of a Human Genome Organization committee which has proposed a unified professional-standard for representing genomic data which, when finalised, will be adopted world-wide. Read more
Graphene oxide as growth factor carriers for meniscus tissue engineering
Damage to the meniscus of the knee leads to increased risk of osteoarthritis. Tissue engineering of a healthy meniscal fibrocartilage offers the opportunity to restore function. Read more
Unravelling the role of Lrig2 during neuromuscular development
Motor nerves connect the spinal cord and brain with muscles in our face, arms, legs and internal organs. The motor nerves send signals which tell these muscles to contract. Read more
On-Demand Regulation of the Transcriptional Activity of Redox Induced Transcription Factors in Cancer Using Bioelectronics
Cancer heterogeneity reduces the effectiveness of many cancer therapies. Therefore, the most promising treatments are those that inhibit several signalling pathways crucial for cancer survival. Read more
Identification of transcriptomic signatures of autism-like neurodevelopmental disorder
The overarching aim of this project is to define transcriptional patterns and identify new genetic elements essential for the correct development of the human brain. Read more
Investigating the cardio-pulmonary impact of airborne nanoplastics
There is growing evidence that humans are exposed to incidental microplastics and nanoplastics (MNPL) particles through inhalation and that the small size of these particles may allow for bioaccumulation and retention in the body. Read more
Investigate the novel therapeutic potential for treating heart failure in diabetes.
Heart failure is the most common cause of mortality in diabetes patients, but current diabetes therapies have a limited impact on the incidence of heart failure in diabetic populations. Read more
Investigating the interaction of La related proteins with colliding ribosomes
The accurate translation of mRNA into the right proteins at the right time and place is a critical cellular biological process for all life. Read more
Chaperones and the response to protein misfolding stress
Misfolded proteins are usually refolded to their functional conformations or degraded by quality control mechanisms. When misfolded proteins evade quality control, they form aggregates that are sequestered to specific sites within cells. Read more
Full exploitation of amyloid PET-MR data for dementia research
Simultaneous PET-MR data acquisition using amyloid radiotracers has utility for future clinical studies such as the development of novel therapeutic interventions for dementia. Read more
Integrating Electrical Fields with Smart Nanoparticles and Biomimetic Hydrogels for Targeted Glioblastoma Therapy
Glioblastoma (GBM) is the most aggressive and lethal primary brain tumour in adults, with a high recurrence rate and limited treatment options. Read more