Bioinformatics PhD Projects, Programmes & Scholarships for Self-funded Students in Manchester

We have 22 Bioinformatics PhD Projects, Programmes & Scholarships for Self-funded Students in Manchester

Identification and characterization of disease-specific subsets of antigen-presenting cells (APC) in inflammatory arthritis

The University of Manchester Faculty of Biology, Medicine and Health

Inflammatory arthritis (IA) can result from non-autoimmune diseases (like crystal arthritis) and from autoimmune diseases like rheumatoid arthritis (RA) and spondyloarthropathies. Read more

Supervisors: Dr S Viatte, Prof A Barton, Mr P Martin

Year round applications PhD Research Project Self-Funded PhD Students Only

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VariantVisualiser: Ensuring precise diagnoses of genetic disorders through the development of intuitive software that facilitates the integration and visualisation of complex informatics with biological and clinical data

The University of Manchester Faculty of Biology, Medicine and Health

Rare diseases affect. This proposal builds on substantial efforts of a Human Genome Organization committee which has proposed a unified professional-standard for representing genomic data which, when finalised, will be adopted world-wide. Read more

Supervisors: Dr S Pettifer, Dr PF Freeman

Year round applications PhD Research Project Self-Funded PhD Students Only

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New methods for modelling radionuclide binding proteins

The University of Manchester Department of Chemistry

The management of radioactively contaminated land and water is a multi-billion pound, 100+ year grand challenge that requires innovation to minimise costs. Read more

Supervisors: Prof S Hay, Dr L Natrajan

Year round applications PhD Research Project Competition Funded PhD Project (UK Students Only)

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Identifying variants impacting splicing of 5’ and 3’ UTRs and underpinning inherited retinal disease

The University of Manchester Faculty of Biology, Medicine and Health

Genomic variation that impacts splicing is well established as a cause of genomic disorders, but is almost exclusively limited to protein-coding exons and introns intersecting protein-coding exons. Read more

Supervisors: Dr J Ellingford, Prof R O'Keefe

15 June 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Determining the biological basis of observed clinical outcomes in juvenile idiopathic arthritis using genetics and multiomics

The University of Manchester Faculty of Biology, Medicine and Health

Juvenile idiopathic arthritis (JIA) is a chronic inflammatory arthritis affecting children and young people with an age of disease onset less than 16 years of age. Read more

Supervisors: Dr J Bowes, Dr J Humphreys

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the genetic basis of immunological overlap between inflammatory diseases

The University of Manchester Faculty of Biology, Medicine and Health

Genetic studies have identified numerous variants within the human genome associated with susceptibility to common complex inflammatory diseases, such as rheumatoid arthritis (RA) and ulcerative colitis (UC). Read more

Supervisors: Mr P Martin, Prof S Eyre, Prof A Morris

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding how to target the T cell compartment within related brain tumours

The University of Manchester Faculty of Biology, Medicine and Health

T cell-based immunotherapy has revolutionised the treatment of many different types of cancer. However, to date, these treatments have not been successful or widely used for the treatment of brain tumours. Read more

Supervisors: Dr K Couper, Prof D Brough, Dr OP Pathmanaban

Year round applications PhD Research Project Self-Funded PhD Students Only

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New Methods for modelling cofactor-dependent enzyme structure and function

The University of Manchester Department of Chemistry

Enzymes are Nature’s catalysts and many used cofactors and/or coenzymes to catalyse their reactions. While AI and homology methods now often allow the useful prediction of protein structure from amino acid sequence, this can be more challenging when the protein/enzyme contain cofactors. Read more

Supervisor: Prof S Hay

27 October 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Identifying critical pathways regulating autoimmunity in immuno-oncology and arthritis patients. Short title: IPADS (Immune PAthways for Drug Side-effects)

The University of Manchester Faculty of Biology, Medicine and Health

Inflammatory arthritis (IA) can result from non-autoimmune diseases (like crystal arthritis) and from autoimmune diseases like rheumatoid arthritis (RA) and spondyloarthropathies (inc. Read more

Supervisors: Dr S Viatte, Prof A Barton, Mr P Martin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Where has all of the carbon gone? Understanding the molecular mechanisms of long-term soil carbon capture

The University of Manchester Department of Earth and Environmental Sciences

Soils, while unglamorous, form the basis of the terrestrial biosphere and are ultimately the source of the majority of the food that we eat, yet fundamental aspects of how soils form and how they store carbon are poorly understood. Read more

Supervisors: Prof D Cameron, Dr S Nixon

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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(MRC DTP CASE) Determination of the role of viruses in the microbiome of biofilms formed in the ear of patients with otitis media

The University of Manchester Faculty of Biology, Medicine and Health

Otitis media (OM) is a very common infection of the middle ear characterised by redness, swelling and build-up of fluid behind the eardrum. Read more

Supervisors: Prof P Vallely, Prof P Klapper, Prof S Lovell, Mrs JN Nichani

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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(MRC DTP CASE) Multiomic evaluation of differential drug response in metastatic breast cancers

The University of Manchester Faculty of Biology, Medicine and Health

Breast cancers are the most common cancers in women. Estrogen Receptor (ER) plays a major role in breast cancer growth. To stop the cancer from growing further, clinically successful ER-targeting therapies like Fulvestrant, etc were developed. Read more

Supervisors: Dr S Nagarajan, Dr HH Harrison, Prof R Clarke, Dr I Iqbal

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Eco-evolutionary dynamics of environmental microbiomes

The University of Manchester Faculty of Biology, Medicine and Health

Include details on the project, outlining the objectives, methods and potential outcomes. Include details of training/techniques to be provided. Read more

Supervisors: Prof M Brockhurst, Dr S Nixon, Dr K Coyte

15 June 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Interpretable machine learning to identify biomarkers from multi-omics data of human cancer

The University of Manchester Department of Computer Science

This project aims to address the critical field of cancer research, a leading cause of death globally. Read more

Supervisor: Dr H Zhou

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Data-driven optimal prediction of bacteria growth

The University of Manchester Department of Mechanical, Aerospace and Civil Engineering

This project is devoted to an AI-based prediction of bacteria growth and its control by antibiotics. In synthetic biology, an improved understanding of bacterial regulatory circuits is required to develop complex biological systems with functionalities beyond existing in nature [1, 2]. Read more

Supervisor: Dr S Utyuzhnikov

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 22 Bioinformatics PhD Projects, Programmes & Scholarships for Self-funded Students in Manchester

Bioinformatics PhD Projects, Programmes & Scholarships for Self-funded Students in Manchester

We have 22 Bioinformatics PhD Projects, Programmes & Scholarships for Self-funded Students in Manchester

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