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We have 30 Cancer Biology PhD Projects, Programmes & Scholarships in Manchester
Cancer Biology PhD Projects, Programmes & Scholarships in Manchester
We have 30 Cancer Biology PhD Projects, Programmes & Scholarships in Manchester
(Bicentenary) Ethnic, geographic, and sociodemographic inequalities in prostate cancer outcomes in the United Kingdom
Background. Prostate cancer is the most common cancer affecting men in the UK, with new cases expected to rise from 55,000 in 2020 to 80,000 annually by 2040. Read more
(Bicentenary) Defining actionable molecular subtypes of ovarian cancer using AI and multi-omic data integration
The Project. High-grade serous ovarian cancer (HGSOC) is the most prevalent and deadly ovarian cancer subtype, primarily driven by TP53 mutations and chromosome instability (CIN). Read more
The role of nuclear localisation of adhesion proteins in tumour growth and invasion
Overview. This project seeks to understand how tumour growth and invasion are controlled by the localisation of certain proteins in cancer cells. Read more
(MB-PhD) Smaller, Better, Faster, Stronger: real-time colorectal cancer management using nanopore sequencing.
Colorectal cancer (CRC) is ranking among the leading causes of cancer-related morbidity and mortality and where early onset is increasing. Read more
(Bicentenary) Developing WSB-1 inhibitors as anti-cancer therapeutic agents
More effective therapeutic approaches targeting tumour metastases remains a clear area on unmet need in cancer research, especially considering the majority of patients unfortunately die from metastatic rather than primary disease. Read more
(MB-PhD) Investigation of signalling from the microenvironment in metastasis of invasive lobular breast cancer
This project focuses on lobular breast cancer (LBC), a less-studied subtype of breast cancer constituting about 15% of diagnoses. Read more
On-Demand Regulation of the Transcriptional Activity of Redox Induced Transcription Factors in Cancer Using Bioelectronics
Cancer heterogeneity reduces the effectiveness of many cancer therapies. Therefore, the most promising treatments are those that inhibit several signalling pathways crucial for cancer survival. Read more
Development and Characterization of Hydrogel-Based Model(s) for Pancreatic Cancer
Pancreatic Ductal Adenocarcinoma (PDAC), which develops from cells lining pancreas ducts, represents 95% of all pancreatic cancer cases. Read more
(Bicentenary) Understanding ethnic differences in breast biology to improve prevention and early detection of cancer in Black women
Breast cancer (BC) is the leading cause of death in UK women aged 35-49. Both the incidence and mortality increase exponentially from the early 30s to the current start of population screening at age 50. Read more
(Bicentenary) Illuminating hidden interactions in ubiquitin-like protein networks for genome stability
The posttranslational modification of proteins is key to virtually all cellular activities, including the DNA damage response, a signalling network critical for maintaining genome stability. Read more
Decoding the epigenetic mechanisms of drug resistance in aggressive breast cancers
Breast cancers pose a major health burden to modern world as being the most common cancer in women. Estrogen receptor (ER), the classical marker of 70% these cancers, is the nuclear receptor important for cancer progression. Read more
Evaluation of Tripterygium wilfordii derived compounds as novel treatments for medulloblastoma.
Medulloblastoma is the most common paediatric malignant brain tumour, accounting for 20% of childhood brain tumours cases per annum in the United Kingdom alone, with approximately one-third of patients dying from the disease worldwide. Read more
Defining the molecular mechanisms of leukaemia chemotherapies
Chemotherapies are usually the backbone of cancer treatment for either curative or palliative patient care. Multiple therapies can be used for the same disease, with the choice of drug dependent on parameters such as the patient’s age and fitness. Read more
(Bicentenary) Modelling Melanoma-Induced Immune Suppression in the Liver Microenvironment Using Mechanistic and Causal Reasoning
Melanoma is an aggressive type of skin cancer associated with an incidence of ≈17500 patients and 2300 deaths per year in the United Kingdom. Read more
(Bicentenary) Characterizing the Immune Microenvironment and Matrisome of Adenoid Cystic Carcinoma
We are seeking a motivated and enthusiastic PhD candidate to investigate the immune microenvironment and matrisome of adenoid cystic carcinoma (ACC), a rare cancer with limited treatment options in the metastatic setting. Read more
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