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Cell Biology / Development PhD Projects, Programs & Scholarships in Manchester

We have 69 Cell Biology / Development PhD Projects, Programs & Scholarships in Manchester

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  Role of cutaneous circadian clocks in gating skin repair
  Dr Q-J Meng, Dr M Sherratt
Application Deadline: 31 March 2019
Biological clocks play a key role by temporally controlling the function of whole organisms (including humans) and individual tissues and cells to be aligned with the rhythmic environment.
  Characterizing the heterogeneity of stem cells in the normal breast and breast tumours
  Dr A Ucar, Prof K R Brennan
Applications accepted all year round
Tissue-restricted stem cells are crucial in supporting the development and maintenance of normal tissues. This is also true for tumours, as only a small population of tumour cells, which are known as cancer stem cells, have the unique stemness features and tumour-initiating capacity.
  Defining the role of UBLylation pathways in the DNA damage response
  Dr C.K Schmidt, Prof A Sharrocks
Application Deadline: 28 February 2019
This 4-year BBSRC Case studentship with AstraZeneca will look at posttranslational modifications with ubiquitin-like proteins (UBLs) within and beyond the DNA damage response (DDR).
  Investigating dysbiosis of hair follicle immune privilege in the pathogenesis of dandruff
  Prof R Paus, Dr J Hardman
Application Deadline: 28 February 2019
Dandruff is characterised by excess skin shedding, hyperkeratosis, parakeratosis and immune cell infiltration (1). It is considered a multifactorial condition with both microbial colonisation and host factors such as sebum production thought to play a role.
  Proteomic approach to understand mitochondrial quality control under normal and stress conditions
  Dr H Lu, Prof S Hubbard
Applications accepted all year round
Defects in protein quality control lead to the accumulation of misfolded and damaged proteins, which play an important role in many diseases (e.g.
  (WIS) How food-borne Listeria monocytogenes overcomes the host defence mechanisms at the single cell level?
  Dr P Paszek, Prof I Roberts
Application Deadline: 28 February 2019
Pathogens have developed intricate ways to overcome the host’s immune system. In this proposal we will study the direct interaction of macrophages with the important food-borne bacterial pathogen Listeria monocytogenes that causes significant human morbidity and mortality.
  (WIS) Determining the role of vascularisation in glomerular development
  Prof R Lennon, Dr R Naylor
Application Deadline: 28 February 2019
The kidney has an essential role in filtering waste and toxins from the blood. When kidney function declines the impact on health is severe.
  (MCRC Non-Clinical) NK cell control of tumour growth dependent on the inflammatory environment
  Prof D Davis, Dr S Zelenay
Application Deadline: 24 February 2019
Arguably, immune therapies for cancer are at a tipping point. Undoubtedly, there are many more successes to come. Understanding the mechanisms behind a strong anti-tumour immune response will surely seed new ideas for immune therapies.
  Designing peptide based hydrogels for 3D-bioprinting applications
  Research Group: Biomaterials
  Prof A Saiani
Application Deadline: 31 May 2019
Hydrogels have shown significant potential as scaffold of 3D cell culture and tissue engineering applications.
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