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We have 10 Developmental Biology PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Manchester



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Manchester  United Kingdom



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Developmental Biology PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Manchester

We have 10 Developmental Biology PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Manchester

As a Developmental Biology PhD student, you’ll have the chance to undertake a detailed research project into the key concepts that underpin the development of an organism. You may be investigating the role of a specific signaling pathway such as Notch, understanding how stem cells acquire their fates or researching the formation of a specific system in humans.

What’s it like to do a PhD in Developmental Biology?

Studying a PhD in Developmental Biology, you’ll become proficient in a range of laboratory skills, especially cell culture as well as techniques from Biochemistry, Cell Biology, and genetics. Due to the complicated ethical concerns surrounding developmental biology, particularly when it comes to studying human embryos, you’ll develop a comprehensive knowledge of ethics.

Some typical research topics in Developmental Biology include:

  • Investigating the development of a particular organ
  • Understanding the development of non-human organisms such as fish
  • Investigating the role of ions and/or growth factors in early embryo development
  • Researching the developmental cause of birth defects
  • How stem cells acquire their fate

Most Developmental Biology programmes are fully funded by the university or a doctoral training programme. These programmes usually have a certain number of advertised projects available, with the proposal previously written by the supervisor determining the scope of the work.

Proposing your own research project is not common in Developmental Biology, mainly due to the challenge of finding funding to cover both your PhD and bench fees.

On a general workday, you’ll likely be in the laboratory preparing or performing experiments, analysing data you collected previously, writing up results and discussing your work with your supervisor and colleagues. You’ll submit your thesis of approximately 60,000 words at the end of your PhD, then have to defend it in a viva exam.

Entry requirements

The entry requirements for most Developmental Biology PhD programmes involve a Masters in a subject directly related to Biology, with at least a Merit or Distinction. If English isn’t your first language, you’ll also need to show that you have the right level of language proficiency.

PhD in Developmental Biology funding options

The research council responsible for funding Developmental Biology PhDs in the UK is the Biotechnology and Biological Sciences Research Council (BBSRC). They provide fully-funded studentships including a stipend for living costs, a consumables budget for bench fees and a tuition fee waiver. Students don’t apply directly to the BBSRC, you apply for advertised projects with this funding attached.

It’s difficult for Developmental Biology PhD students to be ‘self-funded’ due to the additional bench fees. However, if you were planning to fund yourself it might be achievable (depending on your project) through the UK government’s PhD loan and part-time work.

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Investigating monogenic disorders of the protein synthesis machinery

Translation of mRNA into proteins is a critical cellular biological process. We recently described a novel human disorder, now called Faundes-Banka Syndrome (FABAS), caused by heterozygous variants in EIF5A1 that encodes a translation factor. Read more

(EPSRC DTP) Mapping ubiquitin-like protein interactions using tailored photo-crosslinking chemistry

Posttranslational modification (PTM) of proteins is key to virtually all cellular activities. This includes the DNA damage response (DDR), a signalling network critical for facilitating healthy ageing by preventing age-related diseases such as cancer and neurodegenerative pathologies. Read more

Development of deep learning methods and software to infer pathway enrichment from histology images - application to liver fibrosis

Histopathological images are routinely used to characterize complex phenotypes. For example, pathologists regularly study stained images of tissue biopsies for cancer diagnosis as cancer is known to change the morphological features of cells including cell shape and size [1]. Read more

Roles of negative transcriptional regulators in cancer cells

The aim of the project is to investigate how factors involved in mRNA synthesis alter gene expression in human cells. Precise control of transcription and RNA processing is essential for the correct regulation of gene expression in all eukaryotic organisms. Read more

The cellular response to stress: roles in disease and ageing

All living organisms need to adapt to their environment in order to survive and reproduce. They are subjected to many stresses including altered oxygen levels, heat or cold, irradiation, infection and injury. Read more

Mechanistic analysis of neurodevelopmental disorders caused by mutations in the gene RAC1

RAC1 is a signalling protein that regulates many cellular processes and is essential during embryonic development. We recently discovered a novel genetic disease called RAC1-related neurodevelopmental disorder (RAC1-NDD) that results from mutations in the RAC1 gene. Read more
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