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We have 31 Medicine PhD Projects, Programmes & Scholarships in Manchester
Medicine PhD Projects, Programmes & Scholarships in Manchester
We have 31 Medicine PhD Projects, Programmes & Scholarships in Manchester
Integrating Electrical Fields with Smart Nanoparticles and Biomimetic Hydrogels for Targeted Glioblastoma Therapy
Glioblastoma (GBM) is the most aggressive and lethal primary brain tumour in adults, with a high recurrence rate and limited treatment options. Read more
Development and Characterization of Hydrogel-Based Model(s) for Pancreatic Cancer
Pancreatic Ductal Adenocarcinoma (PDAC), which develops from cells lining pancreas ducts, represents 95% of all pancreatic cancer cases. Read more
Bioinspired Nanomaterials Based Miniaturised Soft Robots for High Precision Regiospecific Drug Delivery to Malignant Tumours
Cancer is one of the top global public health challenges, estimated to have caused 10M deaths (2020) according to WHO. Throughout the years, standardised therapeutic protocols have been developed and evolved for the treatment of various types of cancers. Read more
Ocular staining with lissamine green
This project will explore issues related to ocular staining with lissamine green. Read more
Peptide-mediated nanocarrier drug delivery for enhanced brain targeting and treatment of inflammation
This project involves the study of nanoparticles and drug delivery to the brain. The student would be required to make and characterise novel nanoparticles from special lipid molecules of various compositions more suitable for blood-brain barrier (BBB) targeting. Read more
Early life factors in the development of Juvenile idiopathic arthritis
Juvenile idiopathic arthritis (JIA) is an autoimmune inflammatory arthritis with disease onset before the age of 16. Children and young people with this condition develop painful swollen joints and untreated it can lead to long term disability. It may also be associated with comorbid conditions such as uveitis. Read more
Evaluating the risk of biguanides and statins on cancer incidence and mortality rates: a mixed methods study combining pharmacoepidemiological and experimental approaches
In the UK, every two minutes someone is diagnosed with cancer and every four minutes someone dies from it– leading to more than 360,000 new cases and 160,000 deaths annually1. Read more
Genotypic and phenotypic markers of resistance in Aspergillus fumigatus and their impact on outcomes in chronic pulmonary aspergillosis
Chronic pulmonary aspergillosis (CPA) is a progressive infection affecting patients with chronic lung disease. It significantly affects quality of life and mortality. Read more
Model-predictive control of brain plasticity for optimal non-invasive brain stimulation
Neuroplasticity is the mechanism that underpins the brain’s ability to learn or recovery from traumatic events, but also its deterioration underlies several Neurodegenerative diseases and mental illnesses. Read more
Investigating the cardio-pulmonary impact of airborne nanoplastics
There is growing evidence that humans are exposed to incidental microplastics and nanoplastics (MNPL) particles through inhalation and that the small size of these particles may allow for bioaccumulation and retention in the body. Read more
Unravelling the role of Lrig2 during neuromuscular development
Motor nerves connect the spinal cord and brain with muscles in our face, arms, legs and internal organs. The motor nerves send signals which tell these muscles to contract. Read more
Use of polarisation microscopy for investigation of biological samples
Imaging with polarised light can reveal underlying structural properties that cannot be observed with conventional microscopy. Most light sources emit unpolarised light. Read more
Antimicrobial dressings that use invisible light to fight wound infection
Complex wounds (e.g. leg ulcers) are a common condition that produces high levels of morbidity. With >1.6 per 1000 of the UK population affected by complex wounds at any one time, the estimated annual cost to the NHS is >£5 billion. Read more
Application of machine learning algorithms to medical images and clinical/DNA data
This project will develop an automated classifier or the estimation of prognosis of the illness using medical images of the human body, clinical data, and gene information. Read more
Evaluation of Tripterygium wilfordii derived compounds as novel treatments for medulloblastoma.
Medulloblastoma is the most common paediatric malignant brain tumour, accounting for 20% of childhood brain tumours cases per annum in the United Kingdom alone, with approximately one-third of patients dying from the disease worldwide. Read more