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Microbiology PhD Projects, Programs & Scholarships in Manchester

We have 22 Microbiology PhD Projects, Programs & Scholarships in Manchester

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  (WIS) How food-borne Listeria monocytogenes overcomes the host defence mechanisms at the single cell level?
  Dr P Paszek, Prof I Roberts
Application Deadline: 28 February 2019
Pathogens have developed intricate ways to overcome the host’s immune system. In this proposal we will study the direct interaction of macrophages with the important food-borne bacterial pathogen Listeria monocytogenes that causes significant human morbidity and mortality.
  Metals and host-pathogen interactions: the role of metal handling systems in the human gastrointestinal pathogen Campylobacter jejuni
  Dr J Cavet, Dr D Linton
Applications accepted all year round
Campylobacter jejuni is a globally important food-borne pathogen causing an estimated 400-500 million cases of acute human gastroenteritis each year.
  Genetic and immunological basis of rare primary immunodeficiency diseases
  Dr P Arkwright, Dr T Briggs, Prof T Hussell
Applications accepted all year round
Objective. To understand the genetic and explore the functional immune basis of rare primary immunodeficiency diseases. Background.
  Interplay between the translation of upstream open reading frames and ribosome nascent chain-associated factors to control gene expression in eukaryotic cells
  Dr M Pool, Prof G D Pavitt
Applications accepted all year round
Eukaryotic mRNAs typically contain one open reading frame that is translated into protein. However many mRNAs contain additional upstream ORFs (uORFs) that regulate protein expression by controlling the flow of ribosomes to the main ORF, often by regulated reinitiation.
  Towards more sustainable use of phosphorus in UK grasslands considering soil-plant interactions
  Dr V Niasar, Prof D Johnson, Dr S Lee
Applications accepted all year round
This ambitious project will lead to a major shift in how soil phosphorus (P), is managed in UK grasslands.
  Function of miRNAs in formation and regeneration of human hair follicles
  Dr S Kurinna, Dr S Herrick, Prof R Paus
Applications accepted all year round
Recent advances in treating a severe skin condition with autologous transgenic keratinocyte cultures emphasises the importance of molecular mechanisms in selecting subpopulations of skin cells for cutaneous repair [1].
  Functional and mechanistic analysis of mRNA localisation and its role in polarised growth for S. cerevisiae and the pathogenic fungus Aspergillus fumigatus.
  Prof M Ashe, Prof N Read, Prof S Hubbard
Applications accepted all year round
Life threatening fungal diseases annually kill more people than malaria, tuberculosis or breast cancer and Aspergillus fumigatus is the most important human pathogenic filamentous fungus.
  Bacteriophages of Gram positive bacteria: gateways to infection control
  Dr G Xia, Prof J P Derrick
Applications accepted all year round
The rise in antibiotic resistance has prompted a renewed interest in bacteriophage research. A study of the molecular basis for recognition of the bacterial host has applications in detection, vaccine design and control of bacterial infections.
  Photocatalytic and antimicrobial properties of magnetron-sputtered bismuth oxide and its potential for water treatment application
  Dr M Ratova
Applications accepted all year round
Photocatalysis is known as a promising and environmentally sustainable method of water purification. Photocatalytic water treatment is a cheap, yet efficient process as it is initiated simply by light irradiation.
  The production of alcohols as commodity chemicals/ biofuels using yeast as a vehicle
  Prof M Ashe, Prof C M Grant, Dr J-M Schwartz, Dr J Winterburn
Applications accepted all year round
Crude oil represents probably the most important natural resource to industrial nations. As well as fuel, crude oil is used to produce a host of chemicals that govern modern day life.
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