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Molecular Biology PhD Projects, Programs & Scholarships in Manchester

We have 97 Molecular Biology PhD Projects, Programs & Scholarships in Manchester

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  Interplay between the translation of upstream open reading frames and ribosome nascent chain-associated factors to control gene expression in eukaryotic cells
  Dr M Pool, Prof G D Pavitt
Applications accepted all year round

Funding Type

PhD Type

Eukaryotic mRNAs typically contain one open reading frame that is translated into protein. However many mRNAs contain additional upstream ORFs (uORFs) that regulate protein expression by controlling the flow of ribosomes to the main ORF, often by regulated reinitiation.
  British Heart Foundation 4-Year PhD Studentships 2020

Funding Type

PhD Type

British Heart Foundation 4-Year PhD Studentships 2020. Our British Heart Foundation (BHF) 4-year PhD programme provides tailored doctoral training for postgraduate students with an interest in cardiovascular sciences.
  (MRC DTP) The impact of centronuclear myopathy mutations in BIN1 on muscle function and structural organisation
  Prof A Trafford, Dr K Dibb, Dr C Pinali
Application Deadline: 15 November 2019

Funding Type

PhD Type

Transverse tubules are surface membrane invaginations in skeletal and cardiac muscle.
  (MRC DTP) Building the human endometrium in vitro: The role of macrophages in receptive and decidual endometrium to optimise reproductive health
  Dr E Mann, Dr Peter Ruane, Prof J Aplin, Dr L Mohiyiddeen
Application Deadline: 15 November 2019

Funding Type

PhD Type

The human endometrium is a highly dynamic tissue that rapidly generates over ~20 days and differentiates to form a uterus lining receptive to embryo implantation, further transforming into decidua to support embryonic development, or breaking down before regenerating a few days later.
  (MRC DTP) Regulatory chromatin and transcriptional networks impacting on embryonic stem cell differentiation
  Prof A Sharrocks, Prof M Rattray
Application Deadline: 15 November 2019

Funding Type

PhD Type

Embryonic stem cells (ESCs) can give rise to all of the cells in the body so a detailed understanding of how they commit to other cell fates is fundamentally important to understanding both normal human developmental processes and how developmental defects arise.
  Investigation of a Novel Regulator of Plant Yield and Fitness in Plants
  Dr P Gallois, Dr G Johnson
Applications accepted all year round

Funding Type

PhD Type

Autophagy is an incredibly important and highly conserved process across eukaryotes and involves the regulated destruction of unnecessary or damaged components within the cell.
  (MRC DTP) Functional dissection of disease associated genetic loci in rheumatoid arthritis
  Dr G Orozco, Dr S Eyre, Prof A Barton
Application Deadline: 15 November 2019

Funding Type

PhD Type

Rheumatoid arthritis (RA) is a common chronic inflammatory disease characterized by inflammation of the joints and has a high socioeconomic burden.
  (MRC DTP) Modelling inherited developmental ocular disorders using in vitro organoids to understand retinal stem cell fate decisions
  Dr Cerys Manning, Prof G Black
Application Deadline: 15 November 2019

Funding Type

PhD Type

Inherited developmental disorders account for much of childhood visual impairment. During early eye development stem cells must balance fate decisions between proliferation and differentiation at the same time as undergoing cell migration and morphogenesis to prevent such disorders.
  (MRC DTP) Zinc deficiency: a potential contributor to post-stroke complications
  Dr C Lawrence, Dr D Brough, Prof C Smith, Prof S Allan
Application Deadline: 15 November 2019

Funding Type

PhD Type

Stroke remains a leading cause of death and disability worldwide with limited treatment options. In addition to the immediate and common symptoms of stroke such as limb weakness and speech problems, stroke patients often develop complications.
  (MRC DTP) Investigating the role of neuroinflammation and cholesterol metabolism in the progression of brain injury following intracerebral haemorrhage
  Dr P Kasher, Dr D Brough, Prof S Allan, Dr A Parry-Jones
Application Deadline: 15 November 2019

Funding Type

PhD Type

Intracerebral haemorrhage (ICH) is a type of stroke caused by spontaneous bleeding within the brain.
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