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We have 46 Neuroscience PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Manchester
Neuroscience PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Manchester
We have 46 Neuroscience PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Manchester
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Investigation of cortical function by large-scale electrophysiology and computational modelling
A fundamental question in sensory neuroscience is what information sensory neurons convey during natural behaviour (‘sensory coding’). Read more
Early life perturbations and neurological disorders in later life
The formation of the brain involves a complex choreography of events and players during development. While this process is continuous, there are however critical periods in which this process is particularly susceptible to perturbations. Read more
(EPSRC DTP) Developing MRI acquisition and modelling to measure water exchange processes in the brain
Magnetic resonance imaging (MRI) is a non-invasive imaging modality that can produce exquisite images of the brain. Read more
Face identity recognition: Exploring the role of observer motion and motion of viewed person
The ability to identify people around us is crucial to our everyday lives, determining the nature of our social interactions and relationships. Read more
Detecting subtle but clinically significant cognitive change in an ageing population
A major challenge facing dementia research is identifying the earliest indicators of clinically-significant cognitive decline. This research project will be linked to the newly established Memory Assessment & Cognitive Ageing Research Unit (MACARU), led by the primary supervisor. Read more
Mechanistic analysis of neurodevelopmental disorders caused by mutations in the gene RAC1
RAC1 is a signalling protein that regulates many cellular processes and is essential during embryonic development. We recently discovered a novel genetic disease called RAC1-related neurodevelopmental disorder (RAC1-NDD) that results from mutations in the RAC1 gene. Read more
The epigenomic, transcriptional and diagnostic architecture of neurodevelopmental disorders caused by exposure to maternal infection
A fundamental unknown in understanding mechanisms of disease, and therefore improving therapy, is how stressors experienced during critical developmental periods influence the genesis or ‘programming’ of adult disease (Estes & McAllister 2016). Read more
Understanding how altered GABA signalling in the brain's master clock contributes to circadian rhythm disruption in Alzheimer's disease
Our circadian clock is one of the most important timing systems in our body, ensuring that neuronal activity throughout our CNS is appropriately aligned with our homeostatic, physiological, and behavioural needs across the day. Read more
The impact of zinc deficiency on Alzheimers disease
In addition to memory problems, people with Alzheimer’s disease (AD) also experience ‘non-memory’ behavioural symptoms including depression, anxiety, and agitation. Read more
The effect of dementia and aging on the functional and hemodynamic response of the brain
The neuro-vascular unit and the hemodynamic response regulate how the blood supply in our brain meets the metabolic demand of neuronal activity. Read more
Neuronal mechanisms of circadian timekeeping in the diurnal brain
The importance of circadian rhythms in our physiology and behaviour, such as our sleep-wake cycle, feeding schedule, hormone production, etc, to maintain health and wellbeing is well established. Read more
Understanding and optimising motor cortex plasticity
Motor learning is a key skill required at all stages of life but is crucially important for recovery and development. A mechanistic understanding of the biological processes that underpin skill acquisition in healthy and pathological states is an important scientific and clinical goal. Read more
Mechanisms underlying the effects of light and visual stimuli on mood
Light is not only important for vision, light responsiveness extends to fundamental aspects of mood, cognition, and performance. Read more
“Why are models so attractive?” Exploring the use of physical and digital modelmaking in architectural design production.
The process of architectural training has been well documented as being different to typical ways of learning, involving a reflective practice that happens through the interaction with objects (Schön, 1984). Read more
Fluency and Context in Recognition Memory
This project relates to a sort of ‘memory illusion’. On a recognition memory test, increasing the perceptual fluency of a test cue increases the likelihood that the word will be endorsed as ‘familiar’, even if it hasn’t been seen in the study phase (and therefore should have been called ‘new’). Read more