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Obstetrics, Gynaecology & Reproduction PhD Projects, Programs & Scholarships in Manchester

We have 14 Obstetrics, Gynaecology & Reproduction PhD Projects, Programs & Scholarships in Manchester

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Showing 1 to 10 of 14
  (MRC DTP) Peri-conceptional stress signalling through O-GlcNAcylation: effects on the early maternal-embryonic interface
  Prof J Aplin, Prof D Brison, Dr Peter Ruane, Dr A Stevens
Application Deadline: 15 November 2019

Funding Type

PhD Type

Cellular stress during the peri-conceptional period, including that caused by assisted reproductive treatment (ART), can lead to early pregnancy loss, reduced gestation or birthweight and altered postnatal growth, with short- (neurodevelopmental delay) and long- (cardiovascular and metabolic disease)-term health consequences.
  (MRC DTP) Building the human endometrium in vitro: The role of macrophages in receptive and decidual endometrium to optimise reproductive health
  Dr E Mann, Dr Peter Ruane, Prof J Aplin, Dr L Mohiyiddeen
Application Deadline: 15 November 2019

Funding Type

PhD Type

The human endometrium is a highly dynamic tissue that rapidly generates over ~20 days and differentiates to form a uterus lining receptive to embryo implantation, further transforming into decidua to support embryonic development, or breaking down before regenerating a few days later.
  (MRC DTP) Early detection of cancer using identification of volatile metabolites
  Dr J-M Schwartz, Prof P Townsend, Prof S Taylor
Application Deadline: 15 November 2019

Funding Type

PhD Type

Cancer is a disease which more than a third of the world population will get in their life. Different types of cancers have different prevalence and mortality rates, and it has been shown that advances in screening and diagnostic tools reduce mortality.
  (MRC DTP) Placental vascular development in pregnancies complicated by diabetes
  Dr J Myers, Dr E Johnstone, Dr P Brownbill, Dr I Chernyaysky
Application Deadline: 15 November 2019

Funding Type

PhD Type

Maternal diabetes (type 1 & 2) complicates 2-3% of pregnancies. Abnormal fetal growth is common in these pregnancies, manifest as both fetal overgrowth (macrosomia) and fetal growth restriction.
  (MRC DTP) Imaging the microvasculature in preeclampsia
  Dr A Murray, Dr Stephanie Worton, Dr E Johnstone, Dr J Myers
Application Deadline: 15 November 2019

Funding Type

PhD Type

Preeclampsia, new onset high blood pressure and protein in the urine in pregnancy, occurs in 3% of pregnancies and is a common cause of maternal and infant illness and death worldwide.
  (MRC DTP) Delineating the mechanisms underpinning placental dysfunction in advanced maternal age
  Dr A Heazell, Dr M Dilworth, Dr M Desforges, Dr S Greenwood
Application Deadline: 15 November 2019

Funding Type

PhD Type

In the UK, 20% of all births occur to women over the age of 35 (defined as advanced maternal age, AMA) whilst 4% of pregnant women are over the age of 40.
  Understanding the impact of placental aging on placental function
  Dr A Heazell, Dr M Dilworth, Dr M Desforges
Applications accepted all year round

Funding Type

PhD Type

Prolonged pregnancy (>41 weeks gestation) is associated with an increase in perinatal mortality (the death of a baby before or shortly after birth) from a nadir of 1 per 1,000 births at 39 weeks’ to 3 per 1,000 births at 41 weeks which continues to rise beyond this time.
  (MRC DTP) Multimodal data-based modelling of placental function for precision diagnostics in obstetrics medicine
  Dr I Chernyaysky, Prof O Jensen, Dr E Johnstone
Application Deadline: 15 November 2019

Funding Type

PhD Type

The placenta is responsible for sustaining fetal life and enabling fetal growth during pregnancy. It is characterised by a unique complex arrangement of densely packed fetal blood vessels drawing oxygen and nutrients from maternal blood.
  Is there a switch between prostamides and prostaglandins in women with dysmenorrhoea and heavy menstrual bleeding?
  Prof K Marshall, Dr D Fischer, Prof A Nicolaou
Applications accepted all year round

Funding Type

PhD Type

Dysmenorrhoea, painful menstrual cramps, and heavy menstrual bleeding are common debilitating symptoms in women with or without an underlying pelvic pathology.
  Building the human endometrium in vitro: The role of macrophages in receptive and decidual endometrium to optimise reproductive health
  Dr E Mann, Dr Peter Ruane, Prof J Aplin, Dr L Mohiyiddeen
Applications accepted all year round

Funding Type

PhD Type

The human endometrium is a highly dynamic tissue that rapidly generates over ~20 days and differentiates to form a uterus lining receptive to embryo implantation, further transforming into decidua to support embryonic development, or breaking down before regenerating a few days later.
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