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Organic Chemistry PhD Projects, Programs & Scholarships in Manchester

We have 13 Organic Chemistry PhD Projects, Programs & Scholarships in Manchester

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  (MRC DTP) Design of allosteric small molecule inhibitors of fibrosis using advanced molecular simulation techniques
  Dr R A Bryce, Dr K Piper Hanley, Dr R Whitehead
Application Deadline: 15 November 2019

Funding Type

PhD Type

Integrins are a family of protein receptors that play a major role in cell survival, growth and migration. Their function is to transmit signals across the cell membrane by undergoing an elegant large scale structural rearrangement.
  Synthesis and computation to understand and redesign self-assembling carbohydrate materials
  Prof R Field, Dr A Almond
Application Deadline: 30 October 2019

Funding Type

PhD Type

Polysaccharides are widespread in nature and fulfil many important biological functions; they are important foodstuffs and they are exploited as bulk commodities across industry sectors due to their physical properties.
  The chemical glycobiology of carbohydrate metabolism
  Prof R Field, Prof S Flitsch
Applications accepted all year round

Funding Type

PhD Type

Carbohydrates are widespread in nature and fulfil many important biological functions. However, the biology of carbohydrates is much less well explored than that of nucleic acids and proteins.
  Structure based design of novel warheads for use in peptide-drug conjugates
  Dr S Butterworth, Dr A Tirella, Dr D Wiseman
Applications accepted all year round

Funding Type

PhD Type

Chronic Myelomonocytic Leukaemia (CMML) is an orphan disease defined by myeloid dysplasia, myeloproliferation and a malignant expansion of classical monocytes.
  Synthetic and Mechanistic Studies into Enzymatic Degradation of Waste Plastics
  Dr L Wong, Dr C F Blanford
Applications accepted all year round

Funding Type

PhD Type

Plastics are a broad range of solid polymeric materials that have found widespread application as industrial components and consumer goods.
  Synthesis of ribonucleosides using biocatalytic cascades
  Prof N Turner, Prof S Flitsch
Applications accepted all year round

Funding Type

PhD Type

Background – Current state of the art for the synthesis of Anti-Sense Oligonucleotides employs solid phase synthesis. The ASOs are assembled from individual ribonucleotides which themselves are often requiring complicated multistep routes to prepare.
  Programmable Enzymatic Synthesis of Bioactive Compounds
  Prof S Flitsch, Prof P Barran
Applications accepted all year round

Funding Type

PhD Type

The aim of this project is to devise a conceptually novel and general platform that will deliver a step-change in complexity of de novo biosynthetic pathways by moving from manual to automated design, build and test.
  Towards artificial signal transduction in living cells
  Dr S Webb
Applications accepted all year round

Funding Type

PhD Type

The development of synthetic molecules able to transmit biochemical information across phospholipid bilayers could lead to a new type of synthetic biology, where the introduction of orthogonal signalling pathways leads to ‘short-circuiting’ of natural signalling networks in cells.
  Molecular machines that “read” and “write”
  Dr S Webb
Applications accepted all year round

Funding Type

PhD Type

A key feature of biological systems is the storage and transmission of information, which maintains the complex chemical networks and functions within cells.
  Two-dimensional layered materials as catalysts for fine chemical production
  Dr C D'Agostino
Applications accepted all year round

Funding Type

PhD Type

Catalysts are substances that can speed up chemical reactions and/or increase reaction selectivity without consuming themselves. Relative to non-catalytic processes, catalysed reactions perform through more energy efficient routes, in which reactants are able to be used more efficiently.
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