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We have 16 Organic Chemistry PhD Projects, Programmes & Scholarships for Self-funded Students in Manchester
Organic Chemistry PhD Projects, Programmes & Scholarships for Self-funded Students in Manchester
We have 16 Organic Chemistry PhD Projects, Programmes & Scholarships for Self-funded Students in Manchester
Combinatorial Discovery of Peptide Materials as Ice Binding Protein Mimics
Ice Binding Proteins (IBPs) help extremophiles survive in the worlds coldest environments, but are also used by microorganisms to damage hosts by promoting ice formation. Read more
Antimicrobial dressings that use invisible light to fight wound infection
Complex wounds (e.g. leg ulcers) are a common condition that produces high levels of morbidity. With >1.6 per 1000 of the UK population affected by complex wounds at any one time, the estimated annual cost to the NHS is >£5 billion. Read more
Functional Antifouling Electroactive Interfaces for Electrochemical Biosensing
Information on this PhD research area can be found further down this page under the details about the Widening Participation Scholarship given immediately below. Read more
Computational design of tailored open-shell conjugated systems
To be successful, organic electronics devices must be able to replicate and surpass the capabilities of conventional silicon-based electronics. Read more
(MRC DTP) Targetting Extracellular Glycans for antimicrobial therapy and diagnostics
Most drugs have intracellular targets, such as enzyme or transporter inhibitors. Whilst successful, this approach relies on the design of molecules which are not only effective ‘binders’ but are sufficiently membrane permeable. Read more
(MRC DTP) Identifying the molecular interactions that drive mucosal responses to the fungal pathogen Aspergillus fumigatus
Spores of the mould Aspergillus fumigatus cause >3,000,000 chronic and >300,000 invasive diseases annually worldwide. Invasive aspergillosis is the most fatal, with a 50% mortality rate. Read more
(MRC DTP) On a hunt for more powerful, disease-specific anticancer therapy: targeting components of the mitochondrial and endoplasmic reticulum contact sites to prevent cancer initiation and progression
Background. Mitochondria and endoplasmic reticulum (ER) contact sites (MERCs) are subcellular locations where the two organelles are juxtaposed. Read more
(MRC DTP) Design of integrin inhibitors as small molecule modulators of fibrosis
Integrins are a family of protein receptors that play a major role in cell survival, growth and migration. Their function is to transmit signals across the cell membrane by undergoing an elegant large scale structural rearrangement. Read more
(MRC DTP) On a quest to find a cure against Alzheimer’s disease: selective demolition of proinflammatory microRNAs
Alzheimer's disease (AD) is characterised by chronic progressive loss of neurons and microglial activation, leading to severe functional impairment. Read more
New Polymer Biomaterials to Expand and Deliver Cells with Animal-Free Technologies
This PhD will seek to discover new polymeric biomaterials which can modulate stem-cell function, and aid in their delivery to either patients, or as cell factories. Read more
Biocatalytic Synthesis and Degradation of Organosilicon Compounds
In synthetic chemistry, there has been increasing prominence in the use of engineered enzymes to execute chemical transformations. Read more
Targeting glycans on the outside of cells, as new therapeutics
Most drugs have intracellular targets (proteins etc). This creates a barrier to how to target a cell, and then get the drug inside the cell. Read more
Synthetic and Mechanistic Studies into Enzymatic Degradation of Waste Plastics
Plastics are a broad range of solid polymeric materials that have found widespread application globally. However, there has been a steady accumulation of discarded plastics and there is now growing awareness that they present a significant hazard to the natural environment and human health. Read more
Photoredox molecular editing for enhanced drug discovery
Molecular editing platforms, the process by which single atoms can be inserted or deleted selectively in or around a molecule’s skeleton, are transformative to synthetic chemists across industry and academia for the streamlined development of new drugs. Read more
Developing novel light-induced in-situ Electron Paramagnetic Resonance (EPR) methods
Light-induced in-situ Electron Paramagnetic Resonance (EPR) studies are a growing field in both continuous wave and pulsed EPR. It can be used to monitor photoactivated chemical and biochemical reactions involving radical reagents, projects or intermediates. Read more
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