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We have 12 Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships for Self-funded Students in Manchester
Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships for Self-funded Students in Manchester
We have 12 Pharmaceutical Chemistry PhD Projects, Programmes & Scholarships for Self-funded Students in Manchester
(MRC DTP) Peptide hydrogels for delivery of therapeutics for ophthalmic applications
"Wet" macular degeneration and related retinal diseases are a leading cause of sight loss, impacting 570,000 people in UK and at least 96M worldwide. Read more
(MRC DTP) Targetting Extracellular Glycans for antimicrobial therapy and diagnostics
Most drugs have intracellular targets, such as enzyme or transporter inhibitors. Whilst successful, this approach relies on the design of molecules which are not only effective ‘binders’ but are sufficiently membrane permeable. Read more
(MRC DTP CASE) An platform for structural Proteomics screening of membrane proteins
Solute carriers (SLCs) are the second largest class of membrane-embedded proteins with over 400 members organised into 66 families. Read more
(MRC DTP) Nanobioelectronics to Overcome Hypoxia: On-Demand Generation and Enhanced Diffusion of Oxygen for Glioblastoma
Glioblastoma (GBM) is an aggressive form of brain tumor and only 5% of patients survive more than 5 years. One of the reasons behind this high mortality is the insufficient cellular oxygenation which reduces the effectiveness of chemo and radiotherapy. Read more
Polymer Materials to Store Biologics at Room Temperature
Biologics are cell and protein-based therapies which are transforming medical outcomes. This spans insulin for diabetes, glucagon-like peptides for obesity, CAR-T cells for cancer and more. Read more
New Polymer Biomaterials to Expand and Deliver Cells with Animal-Free Technologies
This PhD will seek to discover new polymeric biomaterials which can modulate stem-cell function, and aid in their delivery to either patients, or as cell factories. Read more
Understanding and preventing the denaturation of proteins on surfaces in manufacture, storage and delivery of biotherapeutics
Protein and peptide therapeutics are pharmaceutical drug treatments derived from natural sources. They are applied to a range of diseases from diabetes to novel cancer therapies. Read more
Selective Extraction of Radiotherapeutic Metals for Targeted Alpha Cancer Therapy
Saturn_Nuclear_CDT. Nuclear fission produces radioactive isotopes that are considered as waste and are currently disposed. Read more
Targeting glycans on the outside of cells, as new therapeutics
Most drugs have intracellular targets (proteins etc). This creates a barrier to how to target a cell, and then get the drug inside the cell. Read more
Protein self assembly induced by multivalent biological metabolites
In addition to being an energy source in biological reactions, recent discoveries suggest adenosine triphosphate (ATP) also plays a critical role in maintaining cell stability and preventing deleterious cellular processes through modulating biomacromolecular self assembly. Read more
Targeting the mechanism of small GTPase splice variant RAC1B using ligand design
RAC1 is a small GTPase protein that functions as a key signalling node downstream of various microenvironmental signalling pathways. Read more
Laser spectroscopy of isotopes for nuclear environments
Measurements of isotopes and isotope ratios are important in many areas of science and engineering including the nuclear industry, nuclear forensics, environmental sciences and also in medicine. Read more
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