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Pharmaceutical / Medicinal Chemistry PhD Projects, Programs & Scholarships in Manchester

We have 10 Pharmaceutical / Medicinal Chemistry PhD Projects, Programs & Scholarships in Manchester

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  (WIS) The application of novel Top down Mass Spectrometry to uncover targeted mutagenesis of DNA repair proteins for exposomics
  Dr A Povey, Prof P Barran, Prof G Margison
Application Deadline: 28 February 2019
Next generation sequencing of human tumour DNA consistently shows large numbers of mutations scattered throughout the genome (e.g.
  Development of Novel Photoinduced Methods for the Assembly of Nitrogen-Containing Molecules
  Dr D Leonori
Application Deadline: 1 April 2019
A PhD studentship is available at the University of Manchester, in the School of Chemistry, to work with Dr Daniele Leonori on a project in the area of photoredox catalysis and asymmetric synthesis, starting in October 2019.
  Synthetic and Mechanistic Studies into Enzymatic Degradation of Waste Plastics
  Dr L Wong, Dr C F Blanford
Application Deadline: 1 April 2019
Applications are invited for an EPSRC-funded PhD studentship in the general area of biological chemistry. Plastics are a broad range of solid polymeric materials that have found widespread application as industrial components and consumer goods.
  X-ray Spectroscopy Quantification of f-block Electronic Structure
  Dr M Baker, Dr D P Mills
Application Deadline: 28 February 2019
Applicants are invited to pursue a fully funded postgraduate studentship in the research group of Dr. Michael L. Baker and Dr. David Mills at The University of Manchester at Harwell, located alongside the Diamond Light Source and ISIS Neutron and Muon Source near Oxford.
  Structure based design of novel warheads for use in peptide-drug conjugates
  Dr S Butterworth, Dr A Tirella, Dr D Wiseman
Applications accepted all year round
Chronic Myelomonocytic Leukaemia (CMML) is an orphan disease defined by myeloid dysplasia, myeloproliferation and a malignant expansion of classical monocytes.
  Controlling Reservoir Formation at the Air/Water Interface by Nanoparticle Design: a bridge from Biocompatible Model Systems to Lung Surfactant Function
  Prof J Lawrence, Dr R Campbell
Applications accepted all year round
This PhD project is at the interface between physical chemistry and physical pharmacy and combines the use of several interfacial tools including neutron reflectometry and laser reflection techniques to understand and control the use of nanoparticles in tuning reservoir formation in films at the air/water interface.
  Characterising surface properties of protein biopharmaceutical molecules
  Dr A Golovanov, Dr J Warwicker
Applications accepted all year round
Protein biologicals have great potential for the effective treatment of a wide range of diseases. However, aggregation and instability are inherent issues with all protein pharmaceuticals, which is a problem that can limit their utility and developability.
  Molecular mechanisms of herpesviral infection
  Dr A Golovanov
Applications accepted all year round
Herpes viruses are known to cause a wide range of human diseases, ranging from simple cold sores to cancer, Kaposi Sarcoma. Kaposi Sarcoma, for example, is a type of cancer which affects immunocompromised patients and is endemic in Africa, where it is linked with the spread of HIV infection and AIDS.
  Hypophosphorous acid as a precursor to novel phosphine ligands for catalysis
  Dr A Caffyn
Applications accepted all year round
Reference Number. xx-AC-2018-x-PhD. Project Summary. An industrially relevant new route to functionalised phosphorus ligands for use in catalysis is under development.
  Identification of novel anticonvulsant compounds
  Prof R Baines, Dr S Freeman, Prof S Allan
Applications accepted all year round
Epilepsy and other associated seizures are a significant health concern, occurring in an estimated 1-2% of the world’s population.
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