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Physical Chemistry PhD Projects, Programs & Scholarships in Manchester

We have 36 Physical Chemistry PhD Projects, Programs & Scholarships in Manchester

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  (BBSRC DTP CASE) Optical coherence tomography dynamic light scattering for the measurement of protein aggregation and particulate formation in biologic fluids
  Dr T Waigh, Prof J Lu, Dr M Dickinson
Application Deadline: 31 January 2020

Funding Type

PhD Type

Proteins are susceptible to aggregation during their production which can reduce their bioactivity and prevent their effective formulation in pharmaceutical products.
  Evaluation of Uranium Retention in Geological Minerals at the Sub-Micron Level
  Dr L Natrajan, Prof S Shaw, Prof N Kaltsoyannis
Applications accepted all year round

Funding Type

PhD Type

Uranium (U) is a key contaminant at many nuclear sites and its remediation remains a significant issue, as its speciation and mobility is complex.
  (BBSRC DTP) Discovery, development and application of novel amine and imine biocatalysts for the synthesis of natural products, their analogues and other privileged motifs
  Dr R Whitehead, Prof N Turner, Prof P Barran
Application Deadline: 31 January 2020

Funding Type

PhD Type

This is a cross-disciplinary project, which combines the complementary research expertise of Professor Nick Turner (biocatalysis), Professor Perdita Barran (mass spectrometry) and Dr Roger Whitehead (organic synthesis/biological chemistry).
  (BBSRC DTP) How nature reduces nitrogen – unravelling design features for a nitrogenase mimic
  Dr P O'Malley, Dr S De Visser, Prof M W Anderson
Application Deadline: 31 January 2020

Funding Type

PhD Type

Nitrogen is required for life as a crucial component of both nucleic acids and proteins. Even though nitrogen is the most abundant gas in our atmosphere, our cells can’t use it in its atmospheric form, relying on other processes to "fix" that nitrogen into a biologically available form, ammonia or ammonium.
  (BBSRC DTP) Sharpening up protein NMR: ultra-high resolution experiments
  Prof M Nilsson, Dr A Golovanov, Prof GA Morris
Application Deadline: 31 January 2020

Funding Type

PhD Type

NMR is one of the most important techniques for gaining information on proteins in solution, but the ability to resolve individual NMR signals is a prerequisite for successful analysis.
  (BBSRC DTP) In silico enzymology: A mechanistic study of prenylated flavin-dependent enzymes
  Dr S Hay, Prof D Leys
Application Deadline: 31 January 2020

Funding Type

PhD Type

Many enzymes make use of cofactors to aid in catalysis, as they offer alternative reactivities to the canonical amino acids found in the enzyme active site.
  (BBSRC DTP) Electron Paramagnetic Resonance Pulsed Dipolar Spectroscopy for Structural Biology
  Dr A Bowen, Dr S Hay, Dr M Shanmugam
Application Deadline: 31 January 2020

Funding Type

PhD Type

Electron Paramagnetic Resonance is a rapidly expanding suit of techniques used for the study of complex (bio)molecules that possess spin-active moieties with unaired electrons.
  (BBSRC DTP CASE) Native Mass Spectrometry approaches for Electron and Photon mediated Top Down Sequencing of Biotherapeutics
  Prof P Barran, Prof S Flitsch
Application Deadline: 31 January 2020

Funding Type

PhD Type

Top down mass spectrometry, where the intact protein is introduced into the mass spectrometer and analysed as intact as well as after dissociation, offers several advantages over the more common bottom up approach, where the protein is digested into its constituent peptides before mass spectrometric analysis.
  (BBSRC DTP CASE) Design of a light-driven biocatalyst
  Prof D Leys, Dr S Hay
Application Deadline: 31 January 2020

Funding Type

PhD Type

Illumination is able to unlock a wide range of photochemical reactions, but light is rarely used by living organisms. In fact, to date only three light dependent enzymes have been described in detail.
  (BBSRC DTP CASE) Biophysical characterisation and design of optogenetic control elements
  Dr S Hay, Prof P Barran
Application Deadline: 31 January 2020

Funding Type

PhD Type

Inducible gene ‘switches’ are a core technology in synthetic biology that enable at-will gene expression and the programming of cellular function.
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